Pharmacology of Mitochondria

Häftad, Engelska, 2018

Del 240 i serien Handbook of Experimental Pharmacology

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Beskrivning

This special book is conceived to highlight mitochondrial structural and functional integrity and how they are associated with several human diseases such as cardiovascular, cancer, renal, neurological disorder, and genetic disorders.

Produktinformation

Utgivningsdatum:2018-08-10
Mått:155 x 235 x 26 mm
Vikt:854 g
Format:Häftad
Språk:Engelska
Serie:Handbook of Experimental Pharmacology
Antal sidor:493
Förlag:Springer International Publishing AG
ISBN:9783319861302

Utforska kategorier

Farmakologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik
Hjärt- och kärlsjukdomar inom Medicin

Innehållsförteckning

Mitochondrial Genetics and Ion Transportation: Nuclear transcription factors in the mitochondria: a new paradigm in cellular transformation.- The mitochondrial permeability transition pore and ATP synthase.- Mitochondrial ion fluxes in health and diseases.- Mitochondrial anion channels.- Pharmacology of mitochondrial potassium channels.- Mitochondrial Ca2+ uniporter complex as promising therapeutic target for human diseases and aging.- Mitochondria in Health and Diseases: Mitochondrial Division in Human Disease.- Mitochondrial cholesterol and the paradox in cell death.- Mitochondrial dysfunction in neuromuscular disorders.- Mitochondrial dynamics in cancer.- The emerging role of mitochondrial targeting in kidney disease.- Mitochondrial dynamics as therapeutic targets for treating cardiac disease.- Mitochondria in Alzheimer´s disease and Diabetes-associated Neurodegeneration.- Leber Hereditary Optic Neuropathy, a mitochondrial disease unique in many ways.- Therapeutic Approaches and Mitochondria: Mitochondrial Variation in Health and Disease.- Bioinformatic methods and resources for integrated mitochondrial physiology.- Nanoparticle based therapeutics for mitochondrial dysfunctions.- Mitochondrial respiratory chain complexes as drugs targets.- Targeting the Mitoflash for the Control of Mitochondrial Functions.-Mitochondrial Antioxidant Therapy: Promise or Delusion?- Roles of mitochondrial ROS generation to protect from further prooxidant situations.- MITO-Porter for mitochondrial delivery and mitochondrial functional analysis.- Toxicity of antiepileptic drugs to mitochondria.