Homing Endonucleases and Inteins

AvMarlene Belfort,Barry L. Stoddard

Häftad, Engelska, 2008

Del i serien Nucleic Acids and Molecular Biology

1 652 kr

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Fler format och utgåvor

Inbunden

1 652 kr

Beskrivning

This book provides the first and only comprehensive description and detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies, which are tied together through their frequent fusion and coevolution, have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations.

Produktinformation

Utgivningsdatum:2008-09-22
Mått:155 x 235 x 22 mm
Vikt:604 g
Format:Häftad
Språk:Engelska
Serie:Nucleic Acids and Molecular Biology
Antal sidor:377
Upplaga:2005
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783540852353

Utforska kategorier

Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

Back to Basics: Structure, Function, Evolution and Application of Homing Endonucleases and Inteins.- Homing Endonucleases and the Yeast Mitochondrial ? Locus — A Historical Perspective.- The LAGLIDADG Homing Endonuclease Family.- HNH Endonucleases.- GIY-YIG Homing Endonucleases — Beads on a String.- His-Cys Box Homing Endonucleases.- Group I Introns and Their Maturases: Uninvited, but Welcome Guests.- Group II Intron Homing Endonucleases: Ribonucleoprotein Complexes with Programmable Target Specificity.- Free-Standing Homing Endonucleases of T-even Phage: Freeloaders or Functionaries?.- Function and Evolution of HO and VDE Endonucleases in Fungi.- Engineering Homing Endonucleases for Genomic Applications.- Inteins — A Historical Perspective.- Origin and Evolution of Inteins and Other Hint Domains.- Biochemical Mechanisms of Intein-Mediated Protein Splicing.- The Structure and Function of Intein-Associated Homing Endonucleases.- Harnessing Inteins for Protein Purification and Characterization.- Production of Cyclic Proteins and Peptides.- Inteins for Split-Protein Reconstitutions and Their Applications.- Intein Reporter and Selection Systems.- Industrial Applications of Intein Technology.

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Homing Endonucleases and Inteins

AvMarlene Belfort,Barry L. Stoddard

Häftad, Engelska, 2008

Del i serien Nucleic Acids and Molecular Biology

1 652 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Fler format och utgåvor

Inbunden

1 652 kr

Beskrivning

Produktinformation

Utgivningsdatum:2008-09-22
Mått:155 x 235 x 22 mm
Vikt:604 g
Format:Häftad
Språk:Engelska
Serie:Nucleic Acids and Molecular Biology
Antal sidor:377
Upplaga:2005
Förlag:Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN:9783540852353

Utforska kategorier

Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

Back to Basics: Structure, Function, Evolution and Application of Homing Endonucleases and Inteins.- Homing Endonucleases and the Yeast Mitochondrial ? Locus — A Historical Perspective.- The LAGLIDADG Homing Endonuclease Family.- HNH Endonucleases.- GIY-YIG Homing Endonucleases — Beads on a String.- His-Cys Box Homing Endonucleases.- Group I Introns and Their Maturases: Uninvited, but Welcome Guests.- Group II Intron Homing Endonucleases: Ribonucleoprotein Complexes with Programmable Target Specificity.- Free-Standing Homing Endonucleases of T-even Phage: Freeloaders or Functionaries?.- Function and Evolution of HO and VDE Endonucleases in Fungi.- Engineering Homing Endonucleases for Genomic Applications.- Inteins — A Historical Perspective.- Origin and Evolution of Inteins and Other Hint Domains.- Biochemical Mechanisms of Intein-Mediated Protein Splicing.- The Structure and Function of Intein-Associated Homing Endonucleases.- Harnessing Inteins for Protein Purification and Characterization.- Production of Cyclic Proteins and Peptides.- Inteins for Split-Protein Reconstitutions and Their Applications.- Intein Reporter and Selection Systems.- Industrial Applications of Intein Technology.