Bone Marrow Transplantation

Basic and Clinical Studies

Inbunden, Engelska, 1996

555 kr

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Beskrivning

Since the 1980s, remarkable advances have been made in bone marrow transplantation (BMT), which is now becoming a powerful tool in the treatment of such diseases as leukaemia, aplastic anaemia and congenital immunodeficiency. This text contains information on how to prevent graft rejection, how T cell functions can be completely restored, and how concomitant BMT can prevent the rejection of organ allografts without the use of immunodepressive agents.

Produktinformation

Utgivningsdatum:1996-07-01
Mått:155 x 235 x 25 mm
Vikt:688 g
Format:Inbunden
Språk:Engelska
Antal sidor:331
Förlag:Springer Verlag, Japan
ISBN:9784431701811

Utforska kategorier

Innehållsförteckning

Hematopoietic Stem Cells.- The use of embryonic stem cells to study hematopoietic development in mammals.- Development of blood cells from mouse embryonic stem cells in culture.- Stem cells for lymphocytes: comments on the time and place of commitment of precursors for the T lineage.- Effects of interleukin 12 on hematopoietic stem and progenitor cells.- Identification and characterization of a ligand for receptor protein-tyrosine kinase HTK expressed in hematopoietic cells.- Ex vivo expansion of human primitive hemopoietic progenitors.- Hemopoietic stem cell-stimulating ingredients in kampo (Japanese Herbal) medicine “Juzen-Taiho-To”.- Hematopoietic reconstitution after peripheral blood stem cell transplantation: effects of granulocyte colony-stimulating factor and progenitor cell dose.- Cord-placental blood banking.- Eosinophilic precursors in the fibroreticular network of human thymus.- Growth Factors and Their Receptors.- Biology of Flt3 ligand, a novel regulator of hematopoietic stem and progenitor cells.- Effects of recombinant human thrombopoietin (rhTPO) on thrombopoiesis in bone marrow-transplanted mice.- Physiological and pathological role of gp130, a common signal transducer for IL-6family of cytokines.- Roles of JAK kinases in human GM-CSF receptor.- TGF-ß receptors and signal transduction.- Anti-apoptotic role of protein-tyrosine kinases during granulocytic differentiation of HL-60 cells.- Fibronectin rescues bone marrow cells from apoptosis with IgG.- Cytokine gene expression in peripheral blood mononuclear cells after allogeneic blood stem cell transplantation.- In vivo effects of FLT-3 ligand in mice.- Gene Regulation and Gene Therapy.- Ribozyme-mediated reversal of human pancreatic carcinoma phenotype.- A gene therapy for pancreatic cancer.-Adoptive immunotherapy with cytokine gene-modified cytotoxic T lymphocytes.- Gene transfer to hematopoietic progenitor and stem cells: progress and problems.- Common marmoset as a new preclinical animal model for human gene therapy of hematological disorders.- Development of protein-liposome gene delivery system and its application for the treatment of acquired diseases.- Molecular cloning of a human DEXH box gene homologous to yeast SKI2.- Induction of immune response to lymphoid leukemia cells by M-CSF expression.- Effects of cytokines on the efficiency of gene transfer into murine hematopoietic progenitors.- Bone Marrow Transplantation.- Hematopoietic stem cell transplants from unrelated donors.- Transplantation with purified or unmanipulated mobilized blood stem cells in children.- Transplantation of ex-vivo expanded peripheral blood progenitor cells after high dose chemotherapy in cancer patients.- Graft versus host disease (GVHD) and cryoimmunology.- Transfer of autoimmune thyroiditis and resolution of palmoplantar pustular psoriasis following allogeneic bone marrow transplantation.- Acute graft versus host reaction (GVHR) against major/minor histocompatibility antigens.- Antileukemic effects of interleukin 2 after allogeneic bone marrow transplantation in AKR/J mice.- Detection of minimal residual disease by immunoglobulin heavy chain gene rearrangement analysis in patients with B-ALL after bone marrow transplantation.- Marrow transplantation and stem cell transplantation in 1996 — the developmental perspective —.- The prospects for BMT — from mouse to human —.