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Beskrivning
To metastasize, neoplastic cells dissociate from the primary tumor, enter a circulatory compartment (typically lymphatics or blood vasculature), survive transport, arrest, exit the circulation and finally proliferate at a discontinuous site in response to local growth factors.
Metastasis-Suppressor Genes: A Review and Perspective on an Emerging Field.- The Roles of Map Kinases in Controling Cancer Metastasis.- Tumor Metastasis-Associated Human Mtal Gene: Role in Epithelial Cancer Cell Proplieration and Regulation.- Cooperative Integrin Interactions in the Regulation of Tumor Metastasis.- Brain-Metastasis Associated Genes.- Autocrine Motility Factor and Its Receptor as Regulators of Metastasis.- Nm23 Metastasis Suppressor Gene.- Gene Regulation in Melanoma Metastasis.- Heterochromatin-Associated Protein 1, HP1Hs?, in Breast Cancer Invasion and Metastasis.- Inhibition of Invasion and Metastasis During Specific Amino Acid Restriction Associated with Metastasis Suppressor and Other Gene Changes.- Role of BRMS1 in Breast Carcinoma Metastasis.- The Role of KISS1 in Melanoma Metastasis Suppression.- Osteopontin: A Ras-Regulated Gene That Contributes to Tumor Metastasis.- The Emerging Role for the mRNA Cap-Binding Protein, EIF-4E, in Metastatic Progression.