MicroRNA Cancer Regulation

Advanced Concepts, Bioinformatics and Systems Biology Tools

AvUlf Schmitz,Olaf Wolkenhauer

Häftad, Engelska, 2016

Del 774 i serien Advances in Experimental Medicine and Biology

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Beskrivning

This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology.

Produktinformation

Utgivningsdatum:2016-08-23
Mått:178 x 254 x 20 mm
Vikt:677 g
Format:Häftad
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:346
Förlag:Springer
ISBN:9789402400793

Utforska kategorier

Onkologi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

Preface.- 1 MicroRNAs in human cancer.- 2 Bioinformatics, non-coding RNAs and its possible application in personalized medicine .- 3 MicroRNA target prediction and validation.- 4 MicroRNA-regulated networks: the perfect storm for classical molecular biology, the ideal scenario for systems biology.- 5 The p53/microRNA network in cancer: experimental and bioinformatics approaches.-6 MicroRNAs in melanoma biology.- 7 MicroRNA in the lung.- 8 The E2F1-miRNA cancer progression network.- 9 Modeling of microRNA-transcription factor networks in cancer.- 10 Coordinated networks of microRNAs and transcription factors with evolutionary perspectives.- 11 Mathematical modeling of microRNA-mediated mechanisms of translation repression.- 12 Web resources for microRNA research.- 13 Discovery of microRNA regulatory networks by integrating multidimensional high-throughput data.- 14 Discovering the functional microRNA-mRNA regulatory modules in heterogeneous data.- 15 Elucidating the role of microRNAs in cancer through data mining techniques.- 16 Working together: Combinatorial regulation by microRNAs.