Allergy Bioinformatics

“A comprehensive overview of the molecular basis of allergic diseases, its molecular basis, and how bioinformatics tools can help improve our understanding. This first edition will guide immunologists and professionals dedicated to allergic diseases as they enter this field. This book facilitates a thorough understanding of how bioinformatics tools impact advances in allergic diseases research. It presents an overview of basic aspects and to understand the use of several computational tools.” (Marlon Múnera, World Allergy Organization, WAO Medical Book Reviews, worldallergy.org, September, 2016)

• Allergic Disease Epidemiology.- The Pathogenesis of Allergy: A Brief Introduction.- Genetics and Epigenetic Regulation in Allergic Diseases.- Cross-Reactivity.- From Allergen Extracts to Allergen Genes and Allergen Molecules.- Allergen Gene Cloning.- High Throughput Screening of Allergy.- Surrogate Markers for Allergen-Specific Immunotherapy.- Immune Responses to Allergens in Atopic Disease: Considerations for Bioinformatics.- Antigenicity, Immunogenicity and Allergenicity.- Bioinformatic Classifiers for Allergen Sequence Discrimination.- Strategies for the Modification and Evaluation of Allergenicity.- Bioinformatics Methods to Predict Allergen Epitopes.- Allergen Database.