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The Guide to Investigation of Mouse Pregnancy is the first publication to cover the mouse placenta or the angiogenic tree the mother develops to support the placenta. This much-needed resource covers monitoring of the cardiovascular system, gestational programming of chronic adult disease, epigenetic regulation, gene imprinting, and stem cells.

Offering detailed and integrated information on how drugs, biologics, stress, and manipulations impact pregnancy in the mouse model, this reference highlights techniques used to analyze mouse pregnancy. Joining the ranks of much referenced mouse resources, The Guide to Investigation of Mouse Pregnancy is the only manual providing needed content on pregnancy in animal models for translational medicine and research.

Provides instruction on how to collect pre-clinical data on pregnancy in mouse models for eventual use in human applications Describes the angiogenic tree the mother's uterus develops to support pregnancy and the monitoring of pregnancy-induced cardiovascular changes Educates readers on placental cell lineages, decidual development including immune cells, epigenetic regulation, gene imprinting, stem cells, birth and lactation Discusses how stress, environmental toxicants and other manipulations impact upon placental function and pregnancy success

Despite its importance, youth policy is an often-ignored area of Government planning and legislation, and policy initiatives seem to lack any guiding theme or relevance to the needs of young people. In Youth Policy in the 1990s originally published in 1992, the editors brought together prominent experts in the key areas of youth policy at the time. They provide a critical review of the major issues which implicitly or explicitly affect the world of adolescents and examine to what extent they paint a picture of existing youth policy. The aim was to provide a baseline for a policy on youth in the 1990s.The book recommends the introduction of a Minister for Young People and the use of youth impact statements at national and local level and seeks to provide information and argument for those seeking to plan policy for young people from a corporate or inter-agency perspective.The contributors are all recognized experts in their fields. They tackle their topic first by examining the historical perspective, with a special concentration on the previous decade. Each has paid regard to particular themes – ethnicity, class and gender, and where possible, has brought in material from other countries and cultures. They have then put forward suggestions for future policy.

Despite its importance, youth policy is an often-ignored area of Government planning and legislation, and policy initiatives seem to lack any guiding theme or relevance to the needs of young people. In Youth Policy in the 1990s originally published in 1992, the editors brought together prominent experts in the key areas of youth policy at the time. They provide a critical review of the major issues which implicitly or explicitly affect the world of adolescents and examine to what extent they paint a picture of existing youth policy. The aim was to provide a baseline for a policy on youth in the 1990s.The book recommends the introduction of a Minister for Young People and the use of youth impact statements at national and local level and seeks to provide information and argument for those seeking to plan policy for young people from a corporate or inter-agency perspective.The contributors are all recognized experts in their fields. They tackle their topic first by examining the historical perspective, with a special concentration on the previous decade. Each has paid regard to particular themes – ethnicity, class and gender, and where possible, has brought in material from other countries and cultures. They have then put forward suggestions for future policy.

In EFL contexts, an absence of chances to develop fluency in the language classroom can lead to marked limitations in English proficiency. This volume explores fluency development from a number of different perspectives, investigating measurements and classroom strategies for promoting its development.

In EFL contexts, an absence of chances to develop fluency in the language classroom can lead to marked limitations in English proficiency. This volume explores fluency development from a number of different perspectives, investigating measurements and classroom strategies for promoting its development.

This essential guide reinvents selling for today's B2B market, showing sellers how to overcome stalled deals and customer indecisionBusiness-to-business commerce is broken. Today's customers find themselves overwhelmed by too many options, too much information, and too many obstacles. The result is often an inability to execute any but the safest of purchase decisions, frequently resulting in no decision at all. Could this be the death of sales as we know it?Traditional sales methods are all carefully designed to change the way customers think of sellers-to win customers' business by first gaining their trust. But Brent Adamson and Karl Schmidt argue the real key to B2B sales success is to focus on boosting customers' confidence in themselves and their ability to make large-scale, collective decisions on behalf of their company.Through a combination of powerful research and data, real-world examples, and practical tactics from some of the world's best leaders and sales professionals, The Framemaking Sale provides a blueprint for a completely new approach to selling. Using the authors' unique framemaking method, this book offers a paradigm-shifting perspective on buying and selling with confidence, empowering sales teams and customers alike to thrive in this new world of selling.

This book traces the history of English education in the People's Republic of China from 1949 to the present day. It uses the junior secondary school curriculum as the means to examine how English curriculum developers and textbook writers have confronted the shifting ambiguities and dilemmas over five distinct historical periods.

A WATERSTONES BOOK OF THE YEAR 2024A century ago, a Labour government took power for the first time. Meet the "Wild Men" who led the way...'Superb' -- New Statesman 'Fascinating' -- The Sunday Times.In 1923, the passing of the Act which gave all men the vote opened the door for a radically different sort of government: men from working-class backgrounds who had never before occupied the corridors of power at Westminster. Who were these ‘wild men’? Ramsay MacDonald, their leader and Labour’s first Prime Minster, was the illegitimate son of a Scottish farm labourer; Arthur Henderson was a Scottish iron moulder; J. H. Thomas, a Welsh railwayman; John Wheatley, an Irish-born miner and publican; and William Adamson, a Fife coal miner.The Wild Men - this new edition with a fully updated preface - tells the story of that first Labour administration – its unexpected birth, fraught existence, and controversial downfall – through the eyes of those who found themselves in the House of Commons, running the country for the people. Blending biography and history into a compelling narrative, David Torrance reassesses the UK’s first Labour government a century after it shook up a British establishment still reeling from the War – and how the establishment eventually fought back.This is an extraordinary period in British political history which echoes down the years to our current politics and laid the foundations for the Britain of today.

Rusty Egan, co-founder of Visage and resident DJ at London's iconic Blitz Club, helped define the New Romantic music movement. His autobiography captures the birth of British electronic music, 1980s London nightlife, and collaborations with Midge Ure, Steve Strange, and other pioneers.RustyEgan is one of the most iconic and influential figures in the electronic music industry. His career began in the music industry as a runner atDJM studios, followed by a stint at WEA Records. Rusty collaborated with formerSex Pistols member Glen Matlock, alongside Steve New and MidgeUre, to establish the new wave band Rich Kids. Their debut album, Ghostsof Princes in Towers, released in 1978, achieved both critical acclaim andcommercial success. During the Rich Kids tours, Rusty met Steve Strange.This encounter led to Rusty's concept for a club night at Billy's, a Sohovenue, catering to fashionable punks and showcasing the music they werepassionate about. In 1979, they moved their club night to the Blitz in CoventGarden. As the resident DJ at the Blitz, Rusty played a pivotal rolein introducing British, German, and Japanese electronica to the Britishclub scene, essentially curating the soundtrack for the burgeoning NewRomantic movement.Rusty Egan was instrumental in the formation of the band Visagewith Midge Ure. Steve Strange joined them as the frontman (face and voice), andthe lineup was completed by Billy Currie on keyboards, along with JohnMcGeoch (guitar), Dave Formula (keyboards), and Barry Adamson(bass), all from the band MAGAZINE.Beyond his band work Rusty co-founded the incredibly popular CamdenPalace nightclub in London with Steve Strange, where he continued tochampion and shape the development of electronica in the UK. He alsoestablished Metropolis Music, a publishing and production company,allowing him to create music as well as perform it.Inmore recent news, Rusty released his album Welcome To The Dancefloorin 2017, which featured collaborations with Midge Ure, Tony Hadley, and PeterHook. Furthermore, in June 2024, Demon Records Rusty Egan is stillregularly DJing and in September 2025 will be releasing his new album Romantic to coincidewith this autobiography and the Design Museum's Blitz Club Exhibition centred ofcourse, around Rusty.

Five strangers. One horrific event. What did they see? ‘Assured and engrossing’ The Sunday Times ‘Tightly-plotted, entertaining’ LOUISE CANDLISH ‘Meticulously plotted with an ending I really didn’t see coming.’ SARAH VAUGHAN, author of ANATOMY OF A SCANDAL A gripping new thriller about secrets, obsession and lies When disgraced journalist Jen Hunter witnesses a horrific murder-suicide on Hampstead Heath one February alongside four strangers, she is compelled to find out what really happened that day. They all saw Daniel kill his girlfriend, Vicky – but can they trust their own memories?Jen’s best friend, Bex, is worried about her. She knows Jen hasn’t always been the most stable of women. She knows about the lies. She knows why Jen lost her job at the paper.As the lives of the Parliament Hill witnesses begin to unravel, one thing becomes clear: there is more to what happened that day on the heath. And Jen needs to find out the truth – even at a cost.

Recent years have seen an enormous surge of interest in fiber arts, with works made of thread on display in art museums around the world. But this art form only began to transcend its origins as a humble craft in the late nineteenth and early twentieth centuries, and it wasn't until the 1950s and 1960s that artists used the fiber arts to build critical practices that challenged the definitions of painting, drawing, and sculpture. One of those artists was Lenore Tawney.Raised and trained in Chicago before she moved to New York, Tawney (1907-2007) had a storied career. She was known for employing an ancient Peruvian gauze weave technique to create a painterly effect that appeared to float in space rather than cling to the wall, as well as for being one of the first artists to blend sculptural techniques with weaving practices and, in the process, pioneered a new direction in fiber art. Despite her prominence on the New York art scene, however, she has only recently begun to receive her due from the greater art world. Accompanying a retrospective at the John Michael Kohler Art Center, this catalog features a comprehensive biography of Tawney, additional essays on her work, and two hundred full-color illustrations, making it of interest to contemporary artists, art historians, and the growing audience for fiber art.

How do we judge whether we should be willing to follow the views of experts or whether we ought to try to come to our own, independent views? This book seeks the answer in medieval philosophical thought.In this engaging study into the history of philosophy and epistemology, Peter Adamson provides an answer to a question as relevant today as it was in the medieval period: how and when should we turn to the authoritative expertise of other people in forming our own beliefs? He challenges us to reconsider our approach to this question through a constructive recovery of the intellectual and cultural traditions of the Islamic world, the Byzantine Empire, and Latin Christendom.Adamson begins by foregrounding the distinction in Islamic philosophy between taqlīd, or the uncritical acceptance of authority, and ijtihād, or judgment based on independent effort, the latter of which was particularly prized in Islamic law, theology, and philosophy during the medieval period. He then demonstrates how the Islamic tradition paves the way for the development of what he calls a "justified taqlīd," according to which one develops the skills necessary to critically and selectively follow an authority based on their reliability. The book proceeds to reconfigure our understanding of the relation between authority and independent thought in the medieval world by illuminating how women found spaces to assert their own intellectual authority, how medieval writers evaluated the authoritative status of Plato and Aristotle, and how independent reasoning was deployed to defend one Abrahamic faith against the other. This clear and eloquently written book will interest scholars in and enthusiasts of medieval philosophy, Islamic studies, Byzantine studies, and the history of thought.

How do we judge whether we should be willing to follow the views of experts or whether we ought to try to come to our own, independent views? This book seeks the answer in medieval philosophical thought.In this engaging study into the history of philosophy and epistemology, Peter Adamson provides an answer to a question as relevant today as it was in the medieval period: how and when should we turn to the authoritative expertise of other people in forming our own beliefs? He challenges us to reconsider our approach to this question through a constructive recovery of the intellectual and cultural traditions of the Islamic world, the Byzantine Empire, and Latin Christendom.Adamson begins by foregrounding the distinction in Islamic philosophy between taqlīd, or the uncritical acceptance of authority, and ijtihād, or judgment based on independent effort, the latter of which was particularly prized in Islamic law, theology, and philosophy during the medieval period. He then demonstrates how the Islamic tradition paves the way for the development of what he calls a "justified taqlīd," according to which one develops the skills necessary to critically and selectively follow an authority based on their reliability. The book proceeds to reconfigure our understanding of the relation between authority and independent thought in the medieval world by illuminating how women found spaces to assert their own intellectual authority, how medieval writers evaluated the authoritative status of Plato and Aristotle, and how independent reasoning was deployed to defend one Abrahamic faith against the other. This clear and eloquently written book will interest scholars in and enthusiasts of medieval philosophy, Islamic studies, Byzantine studies, and the history of thought.

Multilingual China explores the dynamics of multilingualism in one of the most multilingual countries in the world. This edited collection comprises frontline empirical research into a range of important issues that arise from the presence of 55 official ethnic minority groups, plus China’s search to modernize and strengthen the nation’s place in the world order. Topics focus on the dynamics of national, ethnic minority and foreign languages in use, policy making and education, inside China and beyond. Micro-studies of language contact and variation are included, as are chapters dealing with multilingual media and linguistic landscapes. The book highlights tensions such as threats to the sustainability of weak languages and dialects, the role and status of foreign languages (especially English) and how Chinese can be presented as a viable regional or international language.Multilingual China will appeal to academics and researchers working in multilingualism and multilingual education, as well as sinologists keen to examine the interplay of languages in this complex multilingual context.

During infancy, children master the rudiments of communication, including the intricacies of social interaction and the complexities of emotional, gestural, and symbolic expression. This book traces children's developmental path from birth through the third year of life, providing an integrative view of their multifaceted accomplishments.Drawing on

Changing conditions in Higher Education and national funding regimes preceded a proliferation of construction projects in universities between 1996 and 2006. This book reviews a hundred projects between 1996 and 2006, and uses 9 detailed case studies from the author's time in charge of capital projects at the University of Cambridge to show us how these projects were conceived, argued for, designed, procured, managed, constructed, and passed on to building users. Readers with an interest in project management, estate management, University management, or the history of the University of Cambridge will find this fascinating and wide-ranging book to be uniquely valuable.

This sweeping work, at once a panoramic overview and an ambitious critical reinterpretation of European modernism, provides a bold new perspective on a movement that defined the cultural landscape of the early twentieth century. Walter L. Adamson embarks on a lucid, wide-ranging exploration of the avant-garde practices through which the modernist generations after 1900 resisted the rise of commodity culture as a threat to authentic cultural expression. Taking biographical approaches to numerous avant-garde leaders, Adamson charts the rise and fall of modernist aspirations in movements and individuals as diverse as Ruskin, Marinetti, Kandinsky, Bauhaus, Purism, and the art critic Herbert Read. In conclusion, Adamson rises to the defense of the modernists, suggesting that their ideas are relevant to current efforts to think through what it might mean to create a vibrant, aesthetically satisfying form of cultural democracy.

In the mid- 1920s, the heyday of silent film, the epic Western swept Hollywood and the nation. Movie moguls sought to add gravitas to their output with the productions - films they argued offered American audiences authentic history and lessons in citizenship at a time when Hollywood faced criticism for its movies' morals and star scandals. Initially extremely popular, these now nearly forgotten Westerns were hailed by the movie industry's proponents and critics alike for their 'authentic' reconstruction of America's nineteenth-century frontier period and the social benefits in portraying historical episodes foundational to American identity to the melting pot of moviegoers. In Projecting America, the first-ever book on these silent epic Westerns, Patrick Adamson demonstrates how these films indelibly impacted the genre, historical filmmaking, and Hollywood, inviting audiences to accept uncritical visions of Manifest Destiny as accurate history. Drawing on a wealth of primary sources and punctuating his argument with film stills and intertitles, Adamson introduces readers to a variety of epic Westerns, with a particular emphasis on The Covered Wagon (1923), The Iron Horse (1924), and The Vanishing American (1925). These productions depict such key moments as pioneers on the Oregon Trail, the construction of the transcontinental railroad, and challenges faced by Indigenous peoples. Combining close analysis of these films' historiography with exploration of their production and reception, Adamson investigates how the epic Westerns' emergence responded to and informed discourses far beyond those traditionally associated with the Western genre. He demonstrates that these movies not only represent an important chapter in film history but also collectively illustrate how American identity was formed and the motion picture medium was used as a vehicle for mass historical and cultural education. In Projecting America, Adamson deftly shows how epic Westerns, at the heart of the 1920s' pressing debates about cinema's social influence, are integral to a broader understanding of the history of Western films and American identity.

This book considers communication development during the first 18 months of life of infants and summarizes the extensive literature about early parent—infant interactions. It is intended for professionals in speech language pathology and pediatrics.

From the First National People of Color Congress on Environmental Leadership to WTO street protests of the new millennium, environmental justice activists have challenged the mainstream movement by linking social inequalities to the uneven distribution of environmental dangers. Grassroots movements in poor communities and communities of color strive to protect neighborhoods and worksites from environmental degradation and struggle to gain equal access to the natural resources that sustain their cultures.This book examines environmental justice in its social, economic, political, and cultural dimensions in both local and global contexts, with special attention paid to intersections of race, gender, and class inequality. The first book to link political studies, literary analysis, and teaching strategies, it offers a multivocal approach that combines perspectives from organizations such as the Southwest Network for Environmental and Economic Justice and the International Indigenous Treaty Council with the insights of such notable scholars as Devon Peña, Giovanna Di Chiro, and Valerie Kuletz, and also includes a range of newer voices in the field.This collection approaches environmental justice concerns from diverse geographical, ethnic, and disciplinary perspectives, always viewing environmental issues as integral to problems of social inequality and oppression. It offers new case studies of native Alaskans' protests over radiation poisoning; Hispanos' struggles to protect their land and water rights; Pacific Islanders' resistance to nuclear weapons testing and nuclear waste storage; and the efforts of women employees of maquiladoras to obtain safer living and working environments along the U.S.-Mexican border.The selections also include cultural analyses of environmental justice arts, such as community art and greening projects in inner-city Baltimore, and literary analyses of writers such as Jimmy Santiago Baca, Linda Hogan, Barbara Neely, Nez Perce orators, Ken Saro-Wiwa, and Karen Yamashita—artists who address issues such as toxicity and cancer, lead poisoning of urban African American communities, and Native American struggles to remove dams and save salmon. The book closes with a section of essays that offer models to teachers hoping to incorporate these issues and texts into their classrooms. By combining this array of perspectives, this book makes the field of environmental justice more accessible to scholars, students, and concerned readers.