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Very Short Introductions: Brilliant, Sharp, Inspiring In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. By explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also be used by forensic scientists to identify individuals in crime. He also explores issues such as the role of genetic heritability and IQ as well as the changes that occur in the genes of populations during evolution.An ideal guide for anyone curious about what genes are and how genetics can be put to use, this Very Short Introduction demonstrates the ways in which the gene concept has been understood and used by molecular biologists, population biologists, and social scientists around the world. This second edition has been fully updated and contains new sections on the CRISPR method for targeted genetic modification, on DNA profiling, and developments in our understanding of human ancestry using ancient DNA.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Conor McGregor is the biggest star in the fight game. The Dubliner has achieved more in three years with the Ultimate Fighting Championship than anyone in the twenty year history of the organization. From an unknown prospect in 2013 to the first man to hold two world titles simultaneously, McGregor's knockout-filled march through the featherweight and then lightweight rankings sent shockwaves through the world. But as effortless as McGregor's heroics have seemed, his journey was far from smooth and his destiny anything but certain.Just another teenager trading martial arts techniques with his friends in a shed, the seemingly delusional boy packed in his plumbing gig - to the massive anxiety of his parents - to chase a pipe dream with little promise of reward. No one could have guessed he would go on to become the biggest pay-per-view attraction in the world. As a technician and tactician inside the cage, McGregor was something special. Outside of the cage McGregor could draw thousands of screaming fans to press events with his wit and presence. And away from the cameras, McGregor's life was built around a love of treating his friends and a loyalty to his teammates and his hometown.This is not another tale about an athlete who was born exceptional and groomed for success. It is about how one young man, through bloody-minded determination and indomitable spirit, came to change the whole game. Fully updated to put his mega-fight with Floyd Mayweather under the microscope, Notorious: The Life and Fights of Conor McGregor explores not just how the fight game changed Conor McGregor, but how Conor McGregor revolutionized the fight game.

VINNARE AV BRANDSKYDDSFÖRENINGENS INNOVATIONSPRIS 2019! Vad ska du göra om det brinner? Häng med Flamman och Lågan på ett lite läskigt äventyr när de vaknar av den tjutande brandvarnaren och en massa rök! Här får du lära dig nummer 112, hur man ska ta sig ut ur ett rum fyllt med rök och annat som är bra att veta om det börjat brinna.

"Sets the standard for excellence in the field and distinguishes itself as a truly vital and comprehensive book within its domain. The book is enriched by numerous real-world and up-to-date examples, along with insightful case studies, ensuring that the readers gain a holistic understanding of the subject." Dr Arijit Bhattacharya, Associate Professor in Operations & Supply Chain Management, Norwich Business School, UEA

The go-to resource on operations strategy, exploring key activities, processes and decisions adopted by a wide range of businesses

Operations Strategy, 7th edition encourages a thorough understanding of the topic, building on concepts from strategic and operations management to marketing and HR management.

The way an organisation manages their operations strategically can have a huge impact on its prospects – whether large or small, service or manufacturing, for-profit or not-for-profit, international or local. Operations strategy is fundamental to the success of any organisation and a major source of competitive advantage.

The text encourages you to explore the key strategic decisions adopted by a wide range of organisations in different sectors, and is ideal for MBA students, upper-level undergraduates, postgraduates and executives.

"Slack and Lewis have approached the ethical, societal, and environmental issues affecting business operations strategy in a post-pandemic world, with a blend of new chapters and contemporary case studies based on both external and internal contexts – an essential item for any serious Operations Strategy resource list." Jamie Rundle, Senior Lecturer in Management, Nottingham Business School, UK

New to this edition:

More on responsible and sustainable operations brings the book up to date with recent developments, showing how operations impact social, ethical, and environmental issues. Increased emphasis on risk in operations strategy and the importance of external and internal context. Updated with several new examples throughout – now including an even wider range of different types of organisation. Four new case studies (bringing the total to 18) explore real-life practical applications to use in class or individually to ground theoretical concepts: House Partnerships at Concept Design Services, IKEA Looks to the Future, Kaston-Trenton Services, and computer game development at Widescale Studio.

"To me, the textbook of Slack and Lewis is the best in the field of Operations Strategy." Jan de Vries, Professor of Operations Management, University of Groningen, The Netherlands

Gain a comprehensive understanding of essential operations management principles with this easy to read introduction to the subject

"This textbook provides valuable insight into the essentials of directing, designing, delivering and developing operations. For the times we live in, the addition of ‘responsible operations' at the end of each chapter makes the book an essential text for any operations management course."

Dr Philip Davies, Associate Professor of Operations Management Henley Business School.

Operations may not run the world, but it makes the world run

There has never been a more exciting time to study operations management. Fast and frequent changes to the way goods and services are produced and delivered, as well as an increased focus on the social responsibility of operations, present new opportunities and challenges for the business world. Operations management is critical to the success and survival of organisations everywhere, no matter how large or small.

Essentials of Operations Management, 3rd edition is a concise introduction to the subject and an invaluable resource, ideal for undergraduates in business studies, technical or joint degrees, as well as MBA and postgraduate students. Based on Slack, Brandon-Jones and Burgess's leading Operations Management, it focuses on essential core topics, without compromising the authoritative, clear and highly practical approach that has become the trademark of the authors.

Key features:

Revised and updated to reflect the ever-changing world of operations management. Illustrations-based – rooted real-life practice with a wealth of examples showing ‘Operations in Practice' from a variety of businesses and organisations globally. New ‘Responsible Operations' section in every chapter summarises how the topic touches upon social, ethical and environmental issues. Problems and applications – practical exercises at the end of each chapter allow you to reflect on what you have learnt and test your understanding Balanced and international approach – draws on a wide array of examples from organisations in different sectors and industries from around the globe.

Optical coherence tomography (OCT) angiography is an important new imaging modality that is already being used by ophthalmologists in retina centers worldwide. It uses motion as intrinsic contrast, thus obviating the need to inject any intravenous dye. It uses infrared light that is invisible to the patient, and only requires few seconds per scan. This makes it both easier to use and much better tolerated by patients than traditional dye-based fluorescein angiography (FA) and indocyanine green (ICG) angiography.Inside Optical Coherence Tomography Angiography of the Eye Drs. David Huang, Bruno Lumbroso, Yali Jia, and Nadia Waheed include detailed information on clinical applications and fundamental principles needed to understand and use this new technology. This includes information on high-speed OCT systems, algorithms to extract flow contrast, the appearance of the normal eye, the findings in myriad diseases, and tips on how to deal with artifact and pitfalls. The 3-dimensional nature of OCT angiography provides visualization that was not possible before with either FA or ICG and readers will come to appreciate how this enables the visualization of previously difficult to image vascular beds such as the 4 retinal vascular plexuses (radial peripapillary, superficial, intermediate, and deep), the choriocapillaris, and the deeper choroidal vessels.Given its noninvasive nature and ease of use, OCT angiography imaging is rapidly taking an important place in everyday ophthalmology and may soon replace fluorescein angiography in everyday practice.Optical Coherence Tomography Angiography of the Eye is designed to be the definitive text on this cutting-edge technology for the retina specialist and comprehensive ophthalmologist.

The New York Times bestselling classic by beloved author, PBS motivational speaker, and professor Leo Buscaglia, Love is an inspirational collection of essays that has helped millions of readers learn to love by identifying barriers to love and suggesting means to overcome them.Originally published in 1972 and inspired by Buscaglia’s popular and groundbreaking “Love Class” at the University of Southern California, Love is filled with emotional insight about the human condition and provides important steps toward personal growth and fulfillment. Framed by Buscaglia’s renowned lectures on love, the text takes a philosophical approach to the various forms of love that shape the human experience: romantic love, love of others, and self-love. Beloved by readers for decades, the text remains as poignant today as it did upon its original publication.

Curbside Consultation in Cornea and External Disease, Second Edition contains new questions and brief, practical, evidence-based answers to the most frequently asked questions that are posed during a “curbside consultation” between clinicians. Dr. David R. Hardten and associate editors Drs. Mark S. Hansen and Celine Satija have designed this unique reference in which cornea and external disease specialists offer expert advice, preferences, and opinions on tough clinical questions commonly encountered by corneal specialists, ophthalmologists, or residents. The unique Q&A format provides quick access to current information with the simplicity of a conversation between two colleagues. Numerous images, diagrams, and references are included to enhance the text and illustrate clinical diagnoses and treatment plans. Some of the questions that are answered inside the Second Edition include: I have a patient with Fuchs' Endothelial Dystrophy. Is there anything new to improve her vision?What should I do with a young patient with mild keratoconus?How can I help a 47-year-old female who uses artificial tears 6 times daily and continues to complain of dry eyes?A patient presents with corneal ulcer. What work-up and treatment would you recommend?How do I manage a patient that rubbed their eye just after LASIK? What could go wrong?What can I offer a patient that sustained eye trauma and loss of iris tissue?I have a patient with poor vision after DMEK. What went wrong and how do I get better vision for them?Curbside Consultation in Cornea and External Disease: 49 Clinical Questions, Second Edition provides information basic enough for residents while also incorporating expert pearls that even high-volume ophthalmologists will appreciate. Cornea specialists, general ophthalmologists, and residents alike will enjoy the user-friendly and casual format and the expert advice contained within.

Strength Training and Exercise Prescription for Rehabilitation Professionals is a modern, evidence-based, therapeutic exercise textbook written for clinicians, by a clinician. The content aims to fill any gaps in exercise knowledge and truly highlights the application and integration of progressive resistance training into the rehabilitation setting. This book delivers a vast, well-researched exercise library and provides sound guidance on developing a comprehensive exercise program, including exercise selection, prescription, and dosing for any individual.Strength Training and Exercise Prescription for Rehabilitation Professionals details a variety of progressions and regressions that allow a primary movement pattern – the squat, deadlift, bridge, push, pull, and carry – to be performed by individuals of all ages, body types, and experience levels. It considers specific factors that apply to injured populations, like pain, phase of healing, pre-requisite range of motion, and strength requirements. The exercise chapters feature many pieces of resistance training equipment, but also explain how to perform and modify bodyweight exercises to achieve the desired training effect, as access to equipment often varies. High-quality images are paired with step-by-step, written explanations, and valuable coaching cues aim to aid instruction and execution. In addition, it also highlights current evidence for rehabilitation of specific diagnoses, including Anterior Cruciate Ligament (ACL) reconstruction, lower back pain, patella, and Achilles tendinopathy.This textbook is an excellent resource for new clinicians and seasoned professionals who desire concise, factual guidance and reference to support the development of their rehabilitative exercise programs. It would be a worthwhile addition to the curriculum of any physical therapy, chiropractic, or athletic training program, but is also appropriate for anyone that may interact closely with rehabilitation clinicians, like strength and conditioning coaches, personal trainers, exercise physiologists, and other fitness professionals with one common goal: improve quality of care and maximize patient outcomes through exercise.

Improvement was a new concept in seventeenth-century England; only then did it become usual for people to think that the most effective way to change things for the better was not a revolution or a return to the past, but the persistent application of human ingenuity to the challenge of increasing the country's wealth and general wellbeing. Improvements in agriculture and industry, commerce and social welfare, would bring infinite prosperity and happiness. The word improvement was itself a recent coinage. It was useful as a slogan summarising all these goals, and since it had no equivalent in other languages, it gave the English a distinctive culture of improvement that they took with them to Ireland and Scotland, and to their possessions overseas. It made them different from everyone else.The Invention of Improvement explains how this culture of improvement came about. Paul Slack explores the political and economic circumstances which allowed notions of improvement to take root, and the changes in habits of mind which improvement accelerated. It encouraged innovation, industriousness, and the acquisition of consumer goods which delivered comfort and pleasure. There was a new appreciation of material progress as a process that could be measured, and its impact was publicised by the circulation of information about it. It had made the country richer and many of its citizens more prosperous, if not always happier. Drawing on a rich variety of contemporary literature, The Invention of Improvement situates improvement at the centre of momentous changes in how people thought and behaved, how they conceived of their environment and their collective prospects, and how they cooperated in order to change them.

The third edition of this highly successful case book has been expanded and updated to reflect the increasing reliance upon comprehensive case material in the teaching of operations management. The text begins with an introduction to analysing operations management cases. Each of the subsequent parts deals with a key area of operations management and begins with an expanded introduction, allowing the book to serve as a stand alone text for introductory operations management courses.

Kevin Slack sounds the alarm on how America's failed neoliberal regime has given way to a woke oligarchy that has deployed a radical toolkit to rapidly strip away the rights of citizens.Americans often use the words progressive, liberal, and radical more or less interchangeably without understanding their place in American history. Kevin Slack describes the distinct aims of the movements they represent and weighs their consequences for the American republic.Each of the three movements rejected older republican principles of governance in favor of an administrative state, but there were substantial differences between Teddy Roosevelt’s Anglo-Protestant progressive social gospelers, who battled trusts and curbed immigration; Franklin Roosevelt’s and Lyndon Johnson’s secular liberals, who forged a government-business partnership and promoted a civil rights agenda; and the 1960s radicals, who protested corporate influence in the Great Society, liberal hypocrisy on race and gender, and the war in Vietnam. Each sought to overturn what came before.  Following the revolution of the 1960s, elites on both left and right turned against the industrial middle class to erect an oligarchy at home and advance globalization abroad. Each side claimed to serve the interests of disadvantaged or underrepresented groups. Radicals ensconced themselves in bureaucracy and academia to advance their vision of social justice for women and minorities, while neoliberal elites promoted monopoly finance, open borders, and the outsourcing of jobs to benefit consumers. The administrative state became a global American empire, but the neoliberals’ economic and military failures precipitated a crisis of legitimacy. In the “great awokening” that began under Barack Obama, neoliberal elites, including establishment conservatives, openly broke with the populist base of the Republican Party, embraced identity politics, and used COVID-19 and a myth of insurrection to strip away the rights of American citizens. Today, an incompetent kleptocracy is draining the wealthiest and most powerful people in history, thus eroding the foundations of its own empire.

When Kathy was forced to quit her high-flying career in London, she was a wreck - burnt out, anxious, consumed by depression. But she found solace in an unlikely place - the veg patch. She put her hands in the soil and found a way to grow, to sow some small seeds of hope.In Rough Patch, Kathy draws us into the world of the kitchen garden to reflect on the lessons she learnt from the soil, along with sharing recipes inspired by the land. Weaving together her own story of recovery with the year she spent growing and cooking her harvests, Kathy realises that the two are tightly bound together and that reconnecting with the earth could restore her hope and renew her life. Along the way there are tales of marauding pigs, transformative insights from planting leeks, recipes for an unchecked courgette glut and the discovery of why a radish seed is worth staying alive for. The result is a candid, hopeful and sometimes funny story about the healing powers of nature; a quiet manifesto for a more connected life.

As the profession of occupational therapy continues to mature and expand its practice, the measurement of occupational performance is one of the key avenues that all practicing clinicians will need to explore and master. Measuring Occupational Performance: Supporting Best Practice in Occupational Therapy, Third Edition summarizes the measurement tools needed to assess client occupational performance, to provide the best intervention, and to document the effectiveness of that intervention. These measurement tools are not just a compilation of all that are available for measurement relevant to occupational therapy; they are an elite group of tools carefully selected by the editors through a process of rigorous theoretical, clinical, and scientific reasoning.In this Third Edition, Drs. Mary Law, Carolyn Baum, and Winnie Dunn have updated current chapters and added new topics that have not been covered in past editions, such as a chapter on measuring school performance, a key area of practice. Also included is a chapter on measurement principles and development to highlight the concepts common to all the measures included in the text. The Third Edition also has a focus on the best measures and measures that are used most frequently.Features of the Third Edition:Offers insight into the importance of measuring functional performance, methodologies, measurement issues, and best approach for outcome measurementConveys a broad focus on occupational performance and offers examples from a wide range of practice settings and from multiple spots throughout the lifespanExplains the technical aspects of measurement development and methodologies and which components of functioning are to be measured and howDevelops an understanding of the theoretical aspects and evidence for both standardized tests and non-standardized testsInstructors in educational settings can visit www.efacultylounge.com for additional material to be used for teaching in the classroom.New in the Third Edition: Focus on strengths-based approachesMeasures health and disability at both individual and population levels using the International Classification of Functioning, Disability and Health (ICF)An emphasis on evidence-based practice and using evidence from other disciplines, not just from occupational therapyNew chapter focused on school-based practiceNew content on reliability, validity, and responsivenessNew content on goal attainmentAdditional material on decision making in practiceIn this changing health care environment, Measuring Occupational Performance: Supporting Best Practice in Occupational Therapy, Third Edition explains how core values and beliefs can be put into everyday practice and is the essential reference manual for the evidence-based occupational therapy and occupational therapy assistant student and practitioner.

“This book is more than the story of an eccentric, driven woman; it is a window on the country between the Civil War and World War I when great fortunes were made—even by a woman.”—USA TodayA biography of Hetty Green, known as the “Witch of Wall Street,” who dueled with the giants of the Gilded Age and amassed a fortune of $100 million before women had the right to voteA full century before Martha Stewart, Oprah, and Madonna became icons of female entrepreneurship, there was Hetty Green, America’s richest woman, who stood alone among the roguish giants of the Gilded Age as the first lady of capitalism. While derided as “a witch of Wall Street” in her lifetime, today, Hetty ranks near the top of America’s list of greatest financiers.She was a female Citizen Kane and America’s richest woman. She bought and sold real estate and railroads, fought hard and sometimes dirty, cornered markets, and amassed cash reserves to rival the great banks. She was the lone woman among a gallery of Gilded Age rogue heroes-Andrew Carnegie, Jay Gould, J.P. Morgan, John D. Rockefeller, and the Vanderbilts.This new biography looks well beyond the lore and historical prejudices to present a brilliant, ruthless entrepreneur vastly ahead of her time, a financial empire ruler known simply as Hetty.

This acclaimed biography of the Gilded Age’s Queen of Wall Street is “a must-read for all aspiring moguls” (Regina Herzlinger, Harvard Business School).   When J. P. Morgan called a meeting of New York's financial leaders after the stock market crash of 1907, Hetty Green was the only woman in the room. The Guinness Book of World Records memorialized her as the World's Greatest Miser, and, indeed, this unlikely robber baron—who parlayed a comfortable inheritance into a fortune that was worth about 1.6 billion in today's dollars—was frugal to a fault. But in an age when women weren't even allowed to vote, never mind concern themselves with interest rates, she lived by her own rules. In Hetty, Charles Slack reexamines her life and legacy, giving us, at long last, a splendidly “nuanced portrait” (Newsweek) of one of the greatest—and most eccentric—financiers in American history.   This P.S. edition features an extra 16 pages of insights into the book, including author interviews, recommended reading, and more.   “[Hetty’s] wry wit and colorful personality bring humor and pathos to this story. . . . [R]eaders cannot help from cheering for her at every turn.” —Booklist   “An exemplary retelling for a new generation.” —Kirkus Reviews “Entertaining. . . . Slack . . . concentrates on telling a good story and telling it well.” —Publishers Weekly   “Wonderfully detailed.” —Forbes “Page-turning.” —Richmond Times-Dispatch “Fascinating.” —New York Post

Run a world-class business from home

Today''s home office is much more than a desk and a computer. In this easy-to-follow guide, you''ll find out how to set up a connected, collaborative, portable, and secure digital workspace in your home. Produced in conjunction with CNET.com, the place you go for the latest in tech and consumer electronics, this book explains how to get the most out of the latest wireless and Web-based technologies.

Inside, you''ll find 24 self-contained projects, step-by-step instructions, a list of tools needed at the beginning of each project, and hundreds of clear photos and screenshots. With CNET Do-It-Yourself Digital Home Office Projects, you''ll be able to manage a competitive business from the comfort of your home.

Set up a serverConfigure a wireless networkEnable videoconferencingMake free phone calls from your PCCreate a commerce websiteEarn advertising income from your blog or websiteProduce podcastsAnd much more

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.

Get beyond the basics with PowerPoint 2007

Take your PowerPoint skills to the next level with help from this highly visual, easy-to-follow guide. PowerPoint 2007 Graphics & Animation Made Easy shows you how to enhance your presentations with everything from bullets and tables to dynamic slides that come to life on the screen. You'll learn to use the latest tools and techniques such as WordArt, SmartArt, charts, audio, and motion graphics. Discover how easy it is to build professional presentations with rich images, special effects, and high-impact animations that will capture your audience's attention every time you present.

Design unique layouts customized for your needsCreate memorable photo albums with captions, textures, and themesAdd and manipulate clip artDisplay data in graphically rich tables and chartsEnhance text with fills, outlines, and artistic effects using WordArt Highlight important points, people, and objects with shapesTransform content into dynamic graphics using SmartArtAdd punch to your presentations with movies and soundCreate custom animations and impressive special effects Import Excel content quickly and easily into PowerPoint slides

Get beyond the basics with PowerPoint 2007

Take your PowerPoint skills to the next level with help from this highly visual, easy-to-follow guide. PowerPoint 2007 Graphics & Animation Made Easy shows you how to enhance your presentations with everything from bullets and tables to dynamic slides that come to life on the screen. You''ll learn to use the latest tools and techniques such as WordArt, SmartArt, charts, audio, and motion graphics. Discover how easy it is to build professional presentations with rich images, special effects, and high-impact animations that will capture your audience''s attention every time you present.

Design unique layouts customized for your needsCreate memorable photo albums with captions, textures, and themesAdd and manipulate clip artDisplay data in graphically rich tables and chartsEnhance text with fills, outlines, and artistic effects using WordArt Highlight important points, people, and objects with shapesTransform content into dynamic graphics using SmartArtAdd punch to your presentations with movies and soundCreate custom animations and impressive special effects Import Excel content quickly and easily into PowerPoint slides

A multi-disciplinary analysis of the evolution of water politics and policy by an international team of distinguished experts. Water management in the Middle Ages in Europe, its evolution in the USA, the elaboration of the European Water Framework Directive, the British experience of water management, the over-exploitation of African aquifers, and the evolution of the water situation in Southern Africa are all examined.This volume underlines the fact that only an integrative and interdisciplinary understanding can lead to genuinely improved water management practices that will not benefit some social groups at the expense of others.

This volume reviews the way in which, over the centuries, the evolving human presence in Britain has shaped the British landscape and how, in turn, the British landscape has moulded the development of British communities. From the beginnings of human settlement Britain has represented a final frontier for successive waves of colonists, each bringing its own set of cultural adaptations and its own ethos into the landscape. Over time both landscape and culture have matured from raw frontier to settled centre, moulded by the advent of agriculture, towns, and industry, and by streams of migration both within Britain and from outside. The chapters in this book - by archaeologists, historians, and geographers - present an interdisciplinary and accessible account of that long process. Together they trace the various phases of the story, showing how much of it has only recently been unearthed, and how much remains to be discovered.

Improvement was a new concept in seventeenth-century England; only then did it become usual for people to think that the most effective way to change things for the better was not a revolution or a return to the past, but the persistent application of human ingenuity to the challenge of increasing the country''s wealth and general wellbeing. Improvements in agriculture and industry, commerce and social welfare, would bring infinite prosperity and happiness. The wordimprovement was itself a recent coinage. It was useful as a slogan summarising all these goals, and since it had no equivalent in other languages, it gave the English a distinctive culture of improvement that they took with them to Ireland and Scotland, and to their possessions overseas. It made themdifferent from everyone else.The Invention of Improvement explains how this culture of improvement came about. Paul Slack explores the political and economic circumstances which allowed notions of improvement to take root, and the changes in habits of mind which improvement accelerated. It encouraged innovation, industriousness, and the acquisition of consumer goods which delivered comfort and pleasure. There was a new appreciation of material progress as a process that could be measured, and its impact waspublicised by the circulation of information about it. It had made the country richer and many of its citizens more prosperous, if not always happier. Drawing on a rich variety of contemporary literature, The Invention of Improvement situates improvement at the centre of momentous changes in how people thought andbehaved, how they conceived of their environment and their collective prospects, and how they cooperated in order to change them.

The topic of stem cells has a high profile in the media. We''ve made important advances in our scientific understanding, but despite this the clinical applications of stem cells are still in their infancy and most real stem cell therapy carried out today is some form of bone marrow transplantation. At the same time, a scandalous spread of unproven stem cell treatments by private clinics represents a serious problem, with treatments being offered which are backed by limited scientific rationale, and which are at best ineffective, and at worse harmful. This Very Short Introduction introduces stem cells, exploring what they are, and what scientists do with them. Introducing the different types of stem cells, Jonathan Slack explains how they can be used to treat diseases such as retinal degeneration, diabetes, Parkinson''s disease, heart disease, and spinal trauma. He also discusses the important technique of bone marrow transplantation and some other types of current stem cell therapy, used for the treatment of blindness and of severe burns. Slack warns against fake stem cell treatments and discusses how to distinguish real from fake treatments. He also describes the latest scientific progress in the field, and looks forward to what we can expect to happen in the next few yearsVery Short Introductions: Brilliant, Sharp, Inspiring ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

The topic of stem cells has a high profile in the media. We''ve made important advances in our scientific understanding, but despite this the clinical applications of stem cells are still in their infancy and most real stem cell therapy carried out today is some form of bone marrow transplantation. At the same time, a scandalous spread of unproven stem cell treatments by private clinics represents a serious problem, with treatments being offered which are backed by limited scientific rationale, and which are at best ineffective, and at worse harmful. This Very Short Introduction introduces stem cells, exploring what they are, and what scientists do with them. Introducing the different types of stem cells, Jonathan Slack explains how they can be used to treat diseases such as retinal degeneration, diabetes, Parkinson''s disease, heart disease, and spinal trauma. He also discusses the important technique of bone marrow transplantation and some other types of current stem cell therapy, used for the treatment of blindness and of severe burns. Slack warns against fake stem cell treatments and discusses how to distinguish real from fake treatments. He also describes the latest scientific progress in the field, and looks forward to what we can expect to happen in the next few yearsVery Short Introductions: Brilliant, Sharp, Inspiring ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Very Short Introductions: Brilliant, Sharp, Inspiring Throughout history plague has been the cause of many major catastrophes. It was responsible for the ''Plague of Justinian'' in 542, the Black Death of 1348, and the Great Plague of London in 1665, as well as for devastating epidemics in China and India between the 1890s and 1920s. In the 21st century Coronavirus pandemics have served as a powerful reminder that we have not escaped the global impact of epidemic diseases. In this Very Short Introduction, Paul Slack takes a global approach to explore the historical and social impact of plague over the centuries, looking at the ways in which it has been interpreted, and the powerful images it has left behind in art and literature. Examining what plague meant for those who suffered from it, and how governments began to fight against it, he demonstrates the impact plague has had on modern notions of public health, and how it has shaped our history. This new edition also includes evidence on the nature of plague taken from recent discoveries in ancient DNA as well as new research on plague in the Middle East. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Very Short Introductions: Brilliant, Sharp, Inspiring Throughout history plague has been the cause of many major catastrophes. It was responsible for the ''Plague of Justinian'' in 542, the Black Death of 1348, and the Great Plague of London in 1665, as well as for devastating epidemics in China and India between the 1890s and 1920s. In the 21st century Coronavirus pandemics have served as a powerful reminder that we have not escaped the global impact of epidemic diseases. In this Very Short Introduction, Paul Slack takes a global approach to explore the historical and social impact of plague over the centuries, looking at the ways in which it has been interpreted, and the powerful images it has left behind in art and literature. Examining what plague meant for those who suffered from it, and how governments began to fight against it, he demonstrates the impact plague has had on modern notions of public health, and how it has shaped our history. This new edition also includes evidence on the nature of plague taken from recent discoveries in ancient DNA as well as new research on plague in the Middle East. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Very Short Introductions: Brilliant, Sharp, Inspiring In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. By explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also be used by forensic scientists to identify individuals in crime. He also explores issues such as the role of genetic heritability and IQ as well as the changes that occur in the genes of populations during evolution. An ideal guide for anyone curious about what genes are and how genetics can be put to use, this Very Short Introduction demonstrates the ways in which the gene concept has been understood and used by molecular biologists, population biologists, and social scientists around the world. This second edition has been fully updated and contains new sections on the CRISPR method for targeted genetic modification, on DNA profiling, and developments in our understanding of human ancestry using ancient DNA. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Very Short Introductions: Brilliant, Sharp, Inspiring In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. By explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also be used by forensic scientists to identify individuals in crime. He also explores issues such as the role of genetic heritability and IQ as well as the changes that occur in the genes of populations during evolution. An ideal guide for anyone curious about what genes are and how genetics can be put to use, this Very Short Introduction demonstrates the ways in which the gene concept has been understood and used by molecular biologists, population biologists, and social scientists around the world. This second edition has been fully updated and contains new sections on the CRISPR method for targeted genetic modification, on DNA profiling, and developments in our understanding of human ancestry using ancient DNA. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

This is a classic study of a disease which had a profound impact on the history of Tudor and Stuart England. Plague was both a personal affliction and a social calamity, regularly decimating urban populations. Paul Slack vividly describes the stresses which plague imposed on individuals, families, and whole communities, and the ways in which people tried to explain, control, and come to terms with it.