Bin Chen – författare

Patterning and Cell Type Specification in the Developing CNS and PNS, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, presents recent advances in genetic, molecular and cellular methods that have generated a massive increase in new information. The book provides a much-needed update to underscore the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neural patterning and cell type specification in the developing central and peripheral nervous systems.

Features leading experts in various subfields as section editors and article authors Contains articles that are peer reviewed to ensure accuracy, thoroughness and scholarship Covers mechanisms which control regional specification, regulate proliferation of neuronal progenitors, control differentiation and survival of specific neuronal subtypes, and control the development of non-neural cells

Cellular Migration and Formation of Neuronal Connections, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. This book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the formation of axons and dendrites and cellular migration.

Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate the formation of axons and dendrites and cellular migration Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity

Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms.

Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Covers disorders of the nervous system that arise through defects in neural development

Neural Circuit and Cognitive Development, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, provides a much-needed update to underscore the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume is devoted mainly to anatomical and functional development of neural circuits and neural systems and cognitive development. Understanding the critical role these changes play in neurodevelopment provides the ability to explore and elucidate the underlying causes of neurodevelopmental disorders and their effect on cognition.

This series is designed to fill the knowledge gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop.

Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms that control the assembly of neural circuits in specific regions of the nervous system and multiple aspects of cognitive development

Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate synapse formation and maintenance during development Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity

This title describes the work behind a major discovery: the establishment of a new pathway that specifically regulates the female meiosis, a process essential for sexual reproduction. It chronicles a new gene mapping method and the cloning and documentation of several types of genes that were proven to have significant influence on the cell cycle. It should be of interest to anyone doing work with fruit flies, both graduate students and principal investigators.

Urban Observation and Social Sensing helps readers see cities in a way they have seldom imagined before. Advanced technologies such as satellites in space, near surface drones, or even smartphones, can be used to explain how a city functions, or why certain areas are more populated than others. It examines the science of capturing city images and information gathered from above the ground combined with the information from social media and mobile data on the ground, and how to make sense of it all. From planning better neighborhoods to understanding how city life affects health, this book is a guide to the future of urban living and the technologies that help navigate it. FeaturesCovers a broad spectrum of urban observation methods in one resource to ensure a thorough understanding of diverse data collection methods.Provides a unique emphasis on social sensing to enable a more holistic and human-centric view of urban landscapes.Includes practical applications to showcase how the data and methodologies can be used in real-world scenarios.Explains the current technologies and methodologies but also offers insights into the future trajectory of urban science.Integrates technological advances with informed urban planning and real-time insights to elucidate a holistic understanding of urban spaces.This is an excellent, insightful resource for researchers, academics, students, and professionals in remote sensing, Geographic Information Systems, urban planning and design, data science, geography, earth science, and those interested in the future of urban living and planning.

Chen examines the Chinese Nationalist government's distinctive support for private Muslim teachers schools between the 1920s and 1940s, and explores the complex relationship between these institutions and the Chinese state during the Republican period. In 1933, the government issued the Teachers Schools Regulations, mandating that all teachers schools be state-run. However, the Nationalists viewed private Muslim teachers schools as valuable allies in their efforts to assert influence in China’s Muslim-dominated northwestern frontier region and deliberately refrained from enforcing the 1933 Teachers Schools Regulations on them. Instead, the government applied the 1933 Amended Private Schools Regulations, which did not specifically address teachers schools, to govern Muslim teachers schools. By charting the evolving dynamics between the Nationalist state and Chinese Hui Muslims, this book reevaluates the Hui Muslims’ role in shaping modern China.Offering crucial context on the role of Islam in modern China, this book is a valuable resource for scholars and students of Chinese history, as well as for policymakers and journalists interested in religion in China.

Grauzone and Completion of Meiosis During Drosophila Oogenesis describes the work behind a major, award winning discovery: the establishment of a new pathway that specifically regulates the female meiosis, a process essential for sexual reproduction.

The current drug development paradigm---sometimes expressed as, ``One disease, one target, one drug''---is under question, as relatively few drugs have reached the market in the last two decades. Meanwhile, the research focus of drug discovery is being placed on the study of drug action on biological systems as a whole, rather than on individual components of such systems. The vast amount of biological information about genes and proteins and their modulation by small molecules is pushing drug discovery to its next critical steps, involving the integration of chemical knowledge with these biological databases. Systematic integration of these heterogeneous datasets and the provision of algorithms to mine the integrated datasets would enable investigation of the complex mechanisms of drug action; however, traditional approaches face challenges in the representation and integration of multi-scale datasets, and in the discovery of underlying knowledge in the integrated datasets. The Semantic Web, envisioned to enable machines to understand and respond to complex human requests and to retrieve relevant, yet distributed, data, has the potential to trigger system-level chemical-biological innovations. Chem2Bio2RDF is presented as an example of utilizing Semantic Web technologies to enable intelligent analyses for drug discovery.Table of Contents: Introduction / Data Representation and Integration Using RDF / Data Representation and Integration Using OWL / Finding Complex Biological Relationships in PubMed Articles using Bio-LDA / Integrated Semantic Approach for Systems Chemical Biology Knowledge Discovery / Semantic Link Association Prediction / Conclusions / References / Authors' Biographies

This book derives an explicit analytical pattern (or framework) that permits the examination and optimization of biogas production systems. It provides a concise overview of the current status of biogas and biogas coupled agricultural systems in China, and introduces evaluation methods for energy efficiency, environmental emissions, economic performance and sustainability assessment approaches. Based on empirical studies, it also explores future options for the system development by focusing on emissions mitigation, biogas energy efficiency and system sustainability. Systematic methods of life cycle assessment and thermodynamic analysis may provide new angles for biogas system evaluation. The system discussed is not only a biogas producer, but also a biogas-linked ecological agricultural system, which has the potential to broaden the applicable scopes of renewable energy and eco-agricultural management. The comprehensive, in-depth knowledge and experience presented provide new analytical approaches for researchers in relevant fields and shed light on the construction and operation of emerging anaerobic digestion and biogas industries. This book is a valuable resource for researchers focusing on biogas system modeling, project managers and policymakers.

This book derives an explicit analytical pattern (or framework) that permits the examination and optimization of biogas production systems. It provides a concise overview of the current status of biogas and biogas coupled agricultural systems in China, and introduces evaluation methods for energy efficiency, environmental emissions, economic performance and sustainability assessment approaches. Based on empirical studies, it also explores future options for the system development by focusing on emissions mitigation, biogas energy efficiency and system sustainability. Systematic methods of life cycle assessment and thermodynamic analysis may provide new angles for biogas system evaluation. The system discussed is not only a biogas producer, but also a biogas-linked ecological agricultural system, which has the potential to broaden the applicable scopes of renewable energy and eco-agricultural management. The comprehensive, in-depth knowledge and experience presented provide new analytical approaches for researchers in relevant fields and shed light on the construction and operation of emerging anaerobic digestion and biogas industries. This book is a valuable resource for researchers focusing on biogas system modeling, project managers and policymakers.