Gokhan Zengin – Författare

This book provides a comprehensive examination of wound healing, starting with the foundational knowledge, including the factors affecting it, and the principles guiding wound healing. It delves into the molecular underpinnings of wound healing, particularly in the context of diabetes, and discusses the challenges of chronic wound healing, including the limitations of existing treatments. It explores the current status and future prospects of nanomaterials, including innovative approaches such as smart 3D printed hydrogels, drug-loaded nanomaterials, and natural bioactive compounds encapsulated within nanomaterials. The book also introduces bio-inspired nanomaterials and their application in wound dressings and tissue regeneration, emphasizing the diagnostic-to-therapeutic strategy continuum. Further chapters cover the specific roles of nano-biomaterials in diabetic wound healing, skin tissue engineering, and the antibacterial properties of nanomaterials that promote wound healing. It looks into engineered nanomaterials, green synthesized nanomaterials for wound healing and cell growth stimulation, and the advanced application of nanocellulose. The role of the immune system in wound healing and strategies for modulating immune responses to enhance healing processes are explored. Lastly, the book addresses the mechanisms of nanomaterials in wound healing, their recent advancements, limitations, future perspectives, and the importance of conducting toxicity studies on nanomaterials used for wound healing. This book is an invaluable resource for researchers, clinical practitioners, and students of biomedical engineering, human physiology, and nanotechnology.Key Features:Offers a thorough exploration of wound healing processes, starting from basic principles to advanced molecular insightsPresents the use of nanomaterials in wound healing, including smart 3D printed hydrogels, drug-loaded nanomaterials, and bioactive compoundsAddresses the challenges associated with chronic wound healing, especially in the context of diabetesIntroduces bio-inspired nanomaterials and their application in wound dressings and tissue regeneration.Examines the role of the immune system in wound healing and discusses strategies to modulate immune responses

This book comprehensively reviews the role of engineered nanomaterials in wound healing. It presents green synthesized nanomaterials for wound healing and cell growth stimulation and explores the advanced application of nanocellulose. The book highlights innovative approaches like smart 3D printed hydrogels and drug-loaded nanomaterials, as well as natural bioactive compounds encapsulated within nanomaterials. It also covers advancements in nanomaterial-based drug delivery systems and the integration of artificial intelligence in wound healing. Further chapters discuss the role of the immune system and the extracellular matrix in wound healing, strategies to modulate immune responses, and recent advancements in tissue engineering. The book addresses the mechanisms, limitations, and future perspectives of nanomaterials in wound healing, and emphasizes the importance of toxicity studies.

This book provides a comprehensive review of the emerging role of extrachromosomal DNA (ecDNA) in cancer, highlighting its significance in tumor progression, oncogene amplification, drug resistance, and clinical applications. Extrachromosomal DNA in Cancer: Mechanisms, Biomarkers, and Therapeutic Implications explores the structural and functional characteristics of ecDNA, emphasizing its role in shaping the genetic and epigenetic landscapes of cancer cells. The book discusses the impact of ecDNA on tumor heterogeneity, metastasis, and immune evasion, providing insights into how ecDNA contributes to cancer evolution and therapeutic resistance. The text also examines cutting-edge imaging techniques, computational approaches, and non-invasive diagnostic applications of ecDNA, highlighting its potential as a biomarker in precision oncology. Additionally, it presents the novel therapeutic strategies targeting ecDNA, addressing challenges and opportunities in integrating these insights into cancer treatment.FeaturesExplores the structural formation and oncogenic role of ecDNA in tumor development and progressionDiscusses the influence of ecDNA on gene expression, epigenetics, and immune modulation in cancerExamines the role of ecDNA in drug resistance, metastasis, and disease recurrenceHighlights advanced imaging, computational tools, and non-invasive diagnostic applications of ecDNAReviews emerging therapeutic strategies targeting ecDNA for improved cancer treatment and personalized medicine This book is intended for researchers and students of cancer biology, molecular biology, and biotechnology.