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28 produkter
28 produkter
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H. Wegele, L. Müller, and J. Buchner: Hsp70 and Hsp90 – A Relay Team for Protein Folding R. Schülein: The Early Stages of the Intracellular Transport of Membrane Proteins: Clinical and Pharmacological Implications L. Schild: The Epithelial Sodium Channel: From Molecule to Disease
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In this volume of Reviews of Physiology, Biochemistry and Pharmacology there a contributions by M.D. Swope, E. Lolis, F.Hofmann, L. Lacinova, N. Klugbauer, M. Hermann, P. Berger, S.S. Shen, J.S. Kim, M.E. Weksler, M. Hirsch-Kauffmann and M.Schweiger.
1 638 kr
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1 105 kr
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H. Wegele, L. Müller, and J. Buchner: Hsp70 and Hsp90 – A Relay Team for Protein Folding R. Schülein: The Early Stages of the Intracellular Transport of Membrane Proteins: Clinical and Pharmacological Implications L. Schild: The Epithelial Sodium Channel: From Molecule to Disease
2 181 kr
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In this volume of Reviews of Physiology, Biochemistry and Pharmacology there a contributions by M.D. Swope, E. Lolis, F.Hofmann, L. Lacinova, N. Klugbauer, M. Hermann, P. Berger, S.S. Shen, J.S. Kim, M.E. Weksler, M. Hirsch-Kauffmann and M. Schweiger.
556 kr
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556 kr
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P.J. Pearson, P.M. Vanhoutte: Vasodilator and Vasoconstrictor Substances Produced by the Endothelium. L. Dux: Muscle Relaxation and Sarcoplasmic Reticulum Function in Different Muscle Types. C.C. Ashley, P.J. Griffith, T.J. Lea, I.P. Mulligan, R.e. Palmer, and S.J. Simnett: Barnacle Muscle: Ca2+ Activation and Mechanics.
556 kr
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R. Levenson: Isoforms of the Na,K-ATPase: Family Members in Search of Function.- E. Petzinger: Transport of Organic Anions in the Liver. An Update on Bile Acid, Fatty Acid, Monocarboxylate, Anionic Amino Acid, Cholephilic Organic Anion and Anionic Drug Transport.- E. Schultz, K.M. McCormick: Skeletal Muscle Satellite Cells.
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K.W. Bock: The Aryl Hydrocarbon or Dioxin Receptor: Biologic and Toxic Responses.-K. Grieshaber, I. Hardewig, U. Kreutzer, and H.-O. Pörtner: Physiological and Metabolic Responses to Hypoxia in Invertebrates.-K.-W. Koch: Calcium as Modulator of Phototransduction in Vertebrate Photoreceptor Cells.
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Contents: R.L. Moss, G.M. Diffee, M.L. Greaser: Contractile Properties of Skeletal Muscle Fibers in Relation to Myofibrillar Protein Isoforms.-J.E. Wilson: Hexokinases.-J. Rassow, N. Pfanner: Molecular Chaperones and Intracellular Protein Translocation.- H. Fuder, E. Muscholl: Heteroreceptor-Mediated Modulation of Noradrenaline and Acetylcholine Release from Peripheral Nerves.
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In this regular issue of Reviews of Physiology the first contribution by Warth and Bleich is on K+ Channels and Colonic Function, the second by Offermanns on Mammalian G-Protein Function in vivo: New Insights Through Altered Expression, and the third contribution by Tenenholz et al. (including one editor of the series) on Structural Determinants of Scorpion Toxin Affinity: The Charybdotoxin (alpha-KTX) Family of K+-channel Blocking Peptides.
556 kr
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W. Ulbricht: Effects of veratridine on sodium currents and fluxes. W. Meyerhof: The elucidation of somatostatin receptor functions: a current view.M. Leist, F. Gantner, g. Künstle and A. Wendel: Cytokine-mediated hepatic apoptosis.
556 kr
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Stjärne: The present review puts the emphasis on two important developments: the discovery that individual postganglionic sympathetic neurons may secrete multiple transmitter substances from different classes of vesicles and by different mechanisms, and the introduction of new techniques which may permit for the first time direct impulse by impulse analysis of transmitter secretion in individual sympathetic nerve varicosities. Illes: Exogenous and endogen opioid peptides elicit a number of effects in the organism, usually by modifying the function of transmitter and hormone systems, for example, activation of multiple opioid receptors. The effects of opioids on transmitter and hormone release have frequently been reviewed. This review gives a detailed overview on the involvement of multiple opioid receptors in these processes. Rothstein: This article gives an overview of the exchange in acidification and transepithelial salt and water transfer in nonepithelial cells. Delineating the exchanger's most important, common features, and concentrating particularly on its role in cell pH and volume regulation.
556 kr
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1 105 kr
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540 kr
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540 kr
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556 kr
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1 073 kr
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556 kr
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In this second special issue on signal transductionleading specialists in their fields again present overviewsof topics related to the highly topicalsubject of signaltransduction. The first contribution, by Keppler, deals withthe biosynthesis, transport, inactivation, and analysis ofleukotrienes. Mohr et al. present an excellent overview ofthe biology of the peptide hormone oxytocin and its role insignal transduction.The review by Holzer describes thesignificance of peptinergic sensory neurons in the controlof vascular functions. In the contribution by Wolf etalthe molecular biology of the Y chromosome is discussed.
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Cook et al.: Phospholipases C and D in Mitogenic SignalTransduction. Moolenaar et al: Lysophosphatidatic Acid: ABioactive Phospholipid with Growth Factor-Like Properties.Kozma et al.: Serine/Threonine Kinases in thePropagation ofthe Early Mitogenic Response. Diringer et al: ARetrospective on Transformation, Growth Control, and somePeculiarities of Lipid Metabolism. Villereal et al.: CalciumSignals in Growth Factor Signal Transduction. Wakabayashi etal.: Structure Function of the Growth Factor-ActivatableNa+/H+ Exchanger. Herrlich et al.: DNA Damage-Induces GeneExpression: Signal Transduction and Relation to GrowthFactor Signaling. Lucibello et al.: Transcription FactorEncoding Oncogenes
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J.A. Roth: Membrane-Bound Catechol-O-Methyltreansferase: A Reevaluation of Its Role in the O-Methylation of the Catecholamine Transmitters. D.J. Benos, S. Cunningham, R.R. Baker, K.B. Beason, Y. Oh, and P.R. Smith: Molecular Characteristics of Amiloride-Sensitive Sodium Channels. D. Pette and G. Vrbov : Adaptation of Mammalian Skeletal Muscle Fibers to Chronic Electrical Stimulation.
556 kr
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556 kr
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Reviews of Physiology Biochemistry and Pharmacology
Special Issue on Signal Transduction in Smooth Muscle
Häftad, Engelska, 2014
556 kr
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The objectives in this special issue are (1) to critically review current information on the mechanisms coupling extracellular regulatory signals to regulation of cross-bridge cycling and proliferation in smooth muscle, and (2) identify significant gaps or unresolved issues that are important topics for future research. The experimental and analytical difficulties discussed above are increasingly recognized and surmounted. Elucidation of the molecular and cellular events underlying the biologal properties of smooth muscle is in the midst of a period of rapid progress. While the reviews reveal many gaps to be filled and illustrate areas of contention, they also capture the excitement of new discoveries.
556 kr
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Reviews of Physiology, Biochemistry and Pharmacology
Special Issue on Cyclic GMP
Häftad, Engelska, 2014
556 kr
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This special volume provides up-to-date information on research dealing with the regulation of the biosynthesis and degradation of cyclic GMP and with the regulation of physiological systems by cyclic GMP. The publication of this volume could not have come at a more appropriate time, with significant work in this area having led to our current understanding of the role of nitric oxide in signal transduction, and the 1998 Nobel Prize in Medicine and Physiology for Furchgott, Murad and Ignarro.Moreover, the introduction in early 1998 of sildenafil (Viagra), a selective inhibitor of a cyclic GMP phosphodiesterase, for the treatment of erectile dysfunction in men represents the first successful therapeutic application of an agent designed to alter the activity of a molecular target in a cyclic GMP pathway.