Hans C. Korting - Böcker

The use of drugs as remedies for various types of diseases has a long tradition; however, it has only been recently recognized that the value of any given compound must be evaluated in light of its benefit to risk ratio. When prescribing drugs, physicians must look at the big picture of the drug's benefits in relation to its side effects and possible toxicity. The aim of this handbook is to compile data from various authors, providing clinicians with data that will optimize their decision making in selecting effective, low-risk drug treatments. It also provides research workers, including physicians, pharmacists, and basic scientists, with a sound basis for increasing knowledge of the risk/benefit ratios of various drugs. Includes detailed assessments of the following types of drugs:Antihypertensive agents Diuretics Anti-diabetic drugs Anticonvulsant drugs Drugs for Parkinson's disease Antihistamines and antiserotonins Cytokines and immunomodulators Non-opioid analgesics and anti-inflammatory agents Antibacterial agents Antiviral agents Drugs used in reproductive endocrinology Systemic drugs for skin diseases Topical liposome drugs Topical glucocorticoids

The use of drugs as remedies for various types of diseases has a long tradition; however, it has only been recently recognized that the value of any given compound must be evaluated in light of its benefit to risk ratio. When prescribing drugs, physicians must look at the big picture of the drug's benefits in relation to its side effects and possible toxicity. The aim of this handbook is to compile data from various authors, providing clinicians with data that will optimize their decision making in selecting effective, low-risk drug treatments. It also provides research workers, including physicians, pharmacists, and basic scientists, with a sound basis for increasing knowledge of the risk/benefit ratios of various drugs. Includes detailed assessments of the following types of drugs:Antihypertensive agents Diuretics Anti-diabetic drugs Anticonvulsant drugs Drugs for Parkinson's disease Antihistamines and antiserotonins Cytokines and immunomodulators Non-opioid analgesics and anti-inflammatory agents Antibacterial agents Antiviral agents Drugs used in reproductive endocrinology Systemic drugs for skin diseases Topical liposome drugs Topical glucocorticoids

Das vorliegende Buch enthält eine aktuelle Übersicht über sexuell übertragbare Erkrankungen (Sexually Transmitted Diseases, STD) und dient vor allem den Belangen der ärztlichen Praxis sowie aller damit befaßten Sparten der Medizin (z.B. Allgemeinmediziner, Dermato-Venerologen, Gynäkologen, Urologen, Fachärzte für Innere Medizin und Kinderheilkunde). Die Darstellung erlaubt in Kürze einen Überblick über die Ätiologie, Pathogenese, Diagnostik und Therapie der einschlägigen Erkrankungen, wobei besonderer Wert auf heutige wichtige Krankheitsbilder, wie z.B. Chlamydien-Infektionen und AIDS, gelegt wurde. Für den weiter interessierten Leser stehen Literaturangaben zur ausführlichen Information zur Verfügung.

The human nail is formed from variably keratinized epithelial structures. The part of the nail organ which is the actual nail plate constitutes the end-product of keratinized cells produced by the matrix. The matrix cells lose their nuclei, become strati­ fied and keratinized, and are added to the firm nail plate al­ ready present. It is usually transparent or translucent, smooth and keratinous in structure, pushed forward by the keratin layer of the nail bed and growing out distally as a free edge over the finger/toe-tip. The transparent nail reveals the pink-coloured nail bed. Usually, a white half-moon shaped lunula is visible, extending under the proximal nail fold. The nail plate consti­ tutes a buttress to pressure. The rate of nail growth is greatest in the second and third decades oflife and declines slightly later. Increased nail growth may be noted during the summer and decreased growth in winter, in evident dependence on the peripheral circulation. Although the nail is not the primary site of attraction at a fleeting glance from others, changes in the nails are quite striking at a second look, and modern freedom of behavior means that changes in the toenails soon become very obvious, especially in women.

Over the last 35 years, synthetic detergents have become increasingly important as skin cleansing agents. With the vast range of soaps and synthetic cleansers available nowadays, doctors and pharmacists are expected to advise on how to cleanse normal as well as diseased skins. Sound advice must include knowledge of the nature, composition and action of the available surfactants and cleanser preparations, the physiology and pathophysiology of the skin surface, the microbial ecology of the skin, and the factors that control the skin flora. Much of this knowledge is the result of recent research. Health care professionals must be familiar, not only with the benefits, but also with the possible adverse effects of synthetic detergents on the human skin (roughness, water loss, etc) and on the environment. This monograph draws upon the expertise of numerous scientists to present a comprehensive view of the subject.

Using a multi-disciplinary approach, this study deals with liposome dermatics from the chemist's, pharmacist's, biologist's as well as clinician's point of view. It features material on the production of liposomes; appropriate raw materials; encapsulation of active ingredients and their possible incorporation into vehicles such as gels; assessment of stability; the fate of liposomes and active ingredients exposed to animal and human skin both in vitro and in vivo; and the activity of topical liposome preparations in normal and inflamed skin in animal and man as well as their efficacy in skin diseases in man.

Bei der Behandlung von Hauterkrankungen spielt die örtliche Anwendung von Arzneimitteln eine zentrale Rolle, alternativ kommt aber auch immer häufiger eine innerliche oder systemische Therapie in Betracht. In vielen Fällen gilt es, topische und systemische Therapie miteinander in sinnvoller Weise zu verbinden. Dieses Buch berücksichtigt beide Therapieformen in adäquater Weise und erweist sich aufgrund seiner knappen, prägnanten Darstellung als sehr praxisorientiert. Auch der Allgemeinmediziner, der zunehmend mit dermatologischen Fragestellungen konfrontiert wird, findet in diesem Buch kompaktes Wissen für die Praxis.