Lihui Wang - Böcker

Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase inhibitors (DNMTi), Histone deacetylases inhibitors (HDACi), Histone lysine demethylases inhibitors (HDMi), Histone lysine methyltransferases inhibitors (HMTi) and drugs regulating the microRNA, long non-coding RNA (lncRNA) or RNA methylation. Finally, recent and future developments of the field of epigenetic regulation are explored.

This is a valuable resource for cancer researchers, clinicians, graduate students and several members of biomedical field who are interested in learning about epigenetic regulation methods to reverse chemo-resistance in cancers.

Presents detailed diagrams of the mechanisms of epigenetic regulation for easy consult Encompasses multiple clinical trial summary diagrams to help readers quickly and clearly get information from clinical trials Provides future perspectives in each section to inspire readers to use epigenetic regulation to overcome chemo-resistance

Proactive Human-Robot Collaboration Toward Human-Centric Smart Manufacturing is driven by an appreciation of manufacturing scenarios where human and robotic agents can understand each other’s actions and conduct mutual-cognitive, predictable, and self-organizing teamwork. Modern factories’ smart manufacturing transformation and the evolution of relationships between humans and robots in manufacturing tasks set the scene for a discussion on the technical fundamentals of state-of-the-art proactive human-robot collaboration; these are further elaborated into the three main steps (i.e., mutual-cognitive and empathic coworking; predictable spatio-temporal collaboration; self-organizing multiagent teamwork) to achieve an advanced form of symbiotic HRC with high-level, dynamic-reasoning teamwork skills. The authors then present a deployment roadmap and several case studies, providing step-by-step guidance for real-world application of these ground-breaking methods which crucially contribute to the maturing of human-centric, sustainable, and resilient production systems. The volume proves to be an invaluable resource that supports understanding and learning for users ranging from upper undergraduate/graduate students and academic researchers to engineering professionals in a variety of industry contexts.

Offers pioneering information on an industry 5.0 topic that has attracted much research interest in recent yearsTakes advantage of a structured and comprehensive approach to seamlessly combine theory, latest technological developments, and their practical applicationsIncludes actionable methods, while conceptualizing future implications for smart manufacturing

With the increasing complexity and dynamism in today’s product design and manufacturing, more optimal, robust and practical approaches and systems are needed to support product design and manufacturing activities. Multi-objective Evolutionary Optimisation for Product Design and Manufacturing presents a focused collection of quality chapters on state-of-the-art research efforts in multi-objective evolutionary optimisation, as well as their practical applications to integrated product design and manufacturing. Multi-objective Evolutionary Optimisation for Product Design and Manufacturing consists of two major sections. The first presents a broad-based review of the key areas of research in multi-objective evolutionary optimisation. The second gives in-depth treatments of selected methodologies and systems in intelligent design and integrated manufacturing.Recent developments and innovations in multi-objective evolutionary optimisation make Multi-objective Evolutionary Optimisation for Product Design and Manufacturing a useful text for a broad readership, from academic researchers to practicing engineers.

With the increasing complexity and dynamism in today’s machine design and development, more precise, robust and practical approaches and systems are needed to support machine design. Existing design methods treat the targeted machine as stationery. Analysis and simulation are mostly performed at the component level. Although there are some computer-aided engineering tools capable of motion analysis and vibration simulation etc., the machine itself is in the dry-run state. For effective machine design, understanding its thermal behaviours is crucial in achieving the desired performance in real situation.Dynamic Thermal Analysis of Machines in Running State presents a set of innovative solutions to dynamic thermal analysis of machines when they are put under actual working conditions. The objective is to better understand the thermal behaviours of a machine in real situation while at the design stage. The book has two major sections, with the first section presenting a broad-based review of the key areas of research in dynamic thermal analysis and simulation, and the second section presents an in-depth treatment of relevant methodology and algorithms, leading to better understanding of a machine in real situation.The book is a collection of novel ideas, taking into account the need for presenting intellectual challenges while appealing to a broad readership, including academic researchers, practicing engineers and managers, and graduate students. Given the essential role of modern machines in factory automation and quality assurance, a book dedicated to the topic of dynamic thermal analysis, and its practical applications to machine design would be beneficial to readers of all design and manufacturing sectors, from machine design to automotive engineering, in better understanding the present challenges andsolutions, as well as future research directions in this important area.

Enterprise Networks and Logistics for Agile Manufacturing presents a focused collection of quality chapters on state-of-the-art research efforts in the areas of enterprise networks and logistics, as well as their practical applications towards agile manufacturing. With the increasing decentralisation of manufacturing systems and outsourcing of processes, more robust and practical approaches and systems are needed to support agile manufacturing operations. Enterprise Networks and Logistics for Agile Manufacturing consists of two major sections: the first presents a broad-based review of the key areas of research in enterprise networks and logistics; the second focuses on an in-depth treatment of a particular methodology or system relevant to the book title. Examples include:• sustainable green supply chain;• value creation and supplier selection;• extended enterprise network management;• reverse logistics; and• innovative supply chain systems.The authors take into account the need to pose intellectual challenges while retaining a balanced approach in terms of scope versus depth and theory versus applications.Enterprise Networks and Logistics for Agile Manufacturing can be beneficial to academic researchers, practicing engineers and managers, and graduate students with an interest in any manufacturing sectors. It can enable them to better understand the present state and future trends of research in this important area, in order to position themselves strategically for future challenges as we enter the era of agile and distributed manufacturing.

With the increasing complexity and dynamism in today’s machine design and development, more precise, robust and practical approaches and systems are needed to support machine design. Existing design methods treat the targeted machine as stationery. Analysis and simulation are mostly performed at the component level. Although there are some computer-aided engineering tools capable of motion analysis and vibration simulation etc., the machine itself is in the dry-run state. For effective machine design, understanding its thermal behaviours is crucial in achieving the desired performance in real situation.Dynamic Thermal Analysis of Machines in Running State presents a set of innovative solutions to dynamic thermal analysis of machines when they are put under actual working conditions. The objective is to better understand the thermal behaviours of a machine in real situation while at the design stage. The book has two major sections, with the first section presenting a broad-based review of the key areas of research in dynamic thermal analysis and simulation, and the second section presents an in-depth treatment of relevant methodology and algorithms, leading to better understanding of a machine in real situation.The book is a collection of novel ideas, taking into account the need for presenting intellectual challenges while appealing to a broad readership, including academic researchers, practicing engineers and managers, and graduate students. Given the essential role of modern machines in factory automation and quality assurance, a book dedicated to the topic of dynamic thermal analysis, and its practical applications to machine design would be beneficial to readers of all design and manufacturing sectors, from machine design to automotive engineering, in better understanding the present challenges andsolutions, as well as future research directions in this important area.

With the increasing complexity and dynamism in today’s product design and manufacturing, more optimal, robust and practical approaches and systems are needed to support product design and manufacturing activities. Multi-objective Evolutionary Optimisation for Product Design and Manufacturing presents a focused collection of quality chapters on state-of-the-art research efforts in multi-objective evolutionary optimisation, as well as their practical applications to integrated product design and manufacturing. Multi-objective Evolutionary Optimisation for Product Design and Manufacturing consists of two major sections. The first presents a broad-based review of the key areas of research in multi-objective evolutionary optimisation. The second gives in-depth treatments of selected methodologies and systems in intelligent design and integrated manufacturing.Recent developments and innovations in multi-objective evolutionary optimisation make Multi-objective Evolutionary Optimisation for Product Design and Manufacturing a useful text for a broad readership, from academic researchers to practicing engineers.

Manufacturing systems and processes are becoming more complex, so more rational decision-making in process control is a necessity. Better information gathering and analysis techniques are needed and condition  monitoring is seen as a framework that will enable these improvements.Condition Monitoring and Control for Intelligent Manufacturing brings together the world’s authorities on condition monitoring to provide a broad treatment of the subject accessible to researchers and practitioners in manufacturing industry.The book presents a review of the key areas of research in machine condition monitoring and control, before focusing on an in-depth treatment of each important technique, from multi-domain signal processing for defect diagnosis to web-based information delivery for real-time control. Researchers in manufacturing and control engineering, as well as practising engineers in industries from automotive to packaging manufacturing will find this book valuable.

Manufacturing has been one of the key areas that support and influence a nation’s economy since the 18th century. Being the primary driving force in economic growth, manufacturing constantly serves as the foundation of and contributes to other industries with products ranging from heavy-duty machinery to hi-tech home electronics. In the past centuries, manufacturing has contributed significantly to modern civilisation and created momentum that is used to drive today’s economy. Despite various revolutionary changes and innovations in the 20th century that contributed to manufacturing advancements, we are still facing new challenges when striving to achieve greater success in winning global competitions. Today, distributed manufacturing is unforeseeably coming into being due to recent business decentralisation and manufacturing outsourcing. Manufacturers are competing in a dynamic marketplace that demands short response time to changing markets and agility in production. In the 21st century, manufacturing is gradually shifting to a distributed environment with increasing dynamism. In order to win a competition, locally or globally, customer satisfaction is treated with priority. This leads to mass customisation and even more complex manufacturing processes, from shop floors to every level along manufacturing supply chains. At the same time, outsourcing has forged a multi-tier supplier structure with numerous small-- medium-sized enterprises involved, where highly-mixed products in small batch sizes are handled simultaneously in job-shop operations.

Manufacturing has been one of the key areas that support and influence a nation’s economy since the 18th century. Being the primary driving force in economic growth, manufacturing constantly serves as the foundation of and contributes to other industries. In the past centuries, manufacturing has contributed to the modern civilisation and created momentum that is continuously driving today’s economy. Despite various revolutionary changes and innovations in the 20th century that contributed to manufacturing advancements, we are facing new challenges when striving to achieve greater success in winning global competitions. Machines and robots, as the constituent components in manufacturing, have contributed significantly to the success of advanced manufacturing. After evolving from the initial mechanisation era where mechanical devices were created to replace human labours to the later automation era where control devices were invented to replace human operations, the history of machines has now entered into the modern era of autonomisation where intelligent devices are being developed in an attempt to eventually replace human decision making. While machines are becoming more and more intelligent through integration with new technologies including sensors, controls, computers and even the Internet, machine structures and theories have also advanced, most noticeably in the area of parallel kinematic machines and micro machines.

Collaborative design has attracted much attention in the research community in recent years. With increasingly decentralized manufacturing systems and processes, more collaborative approaches and systems are needed to support distributed manufacturing operations. "Collaborative Design and Planning for Digital Manufacturing" presents a focused collection of quality chapters on the state-of-the-art research efforts in the area of collaborative design and planning, as well as their practical applications towards digital manufacturing."Collaborative Design and Planning for Digital Manufacturing" provides both a broad-based review of the key areas of research in digital manufacturing, and an in-depth treatment of particular methodologies and systems, from collaborative design to distributed planning, monitoring and control. Recent development and innovations in this area provide a pool of focused research efforts, relevant to a wide readership from academic researchers to practicing engineers.

Enterprise Networks and Logistics for Agile Manufacturing presents a focused collection of quality chapters on state-of-the-art research efforts in the areas of enterprise networks and logistics, as well as their practical applications towards agile manufacturing. With the increasing decentralisation of manufacturing systems and outsourcing of processes, more robust and practical approaches and systems are needed to support agile manufacturing operations. Enterprise Networks and Logistics for Agile Manufacturing consists of two major sections: the first presents a broad-based review of the key areas of research in enterprise networks and logistics; the second focuses on an in-depth treatment of a particular methodology or system relevant to the book title. Examples include:• sustainable green supply chain;• value creation and supplier selection;• extended enterprise network management;• reverse logistics; and• innovative supply chain systems.The authors take into account the need to pose intellectual challenges while retaining a balanced approach in terms of scope versus depth and theory versus applications.Enterprise Networks and Logistics for Agile Manufacturing can be beneficial to academic researchers, practicing engineers and managers, and graduate students with an interest in any manufacturing sectors. It can enable them to better understand the present state and future trends of research in this important area, in order to position themselves strategically for future challenges as we enter the era of agile and distributed manufacturing.

Manufacturing systems and processes are becoming more complex, so more rational decision-making in process control is a necessity. Better information gathering and analysis techniques are needed and condition  monitoring is seen as a framework that will enable these improvements.Condition Monitoring and Control for Intelligent Manufacturing brings together the world’s authorities on condition monitoring to provide a broad treatment of the subject accessible to researchers and practitioners in manufacturing industry.The book presents a review of the key areas of research in machine condition monitoring and control, before focusing on an in-depth treatment of each important technique, from multi-domain signal processing for defect diagnosis to web-based information delivery for real-time control. Researchers in manufacturing and control engineering, as well as practising engineers in industries from automotive to packaging manufacturing will find this book valuable.

Manufacturing has been one of the key areas that support and influence a nation’s economy since the 18th century. Being the primary driving force in economic growth, manufacturing constantly serves as the foundation of and contributes to other industries with products ranging from heavy-duty machinery to hi-tech home electronics. In the past centuries, manufacturing has contributed significantly to modern civilisation and created momentum that is used to drive today’s economy. Despite various revolutionary changes and innovations in the 20th century that contributed to manufacturing advancements, we are still facing new challenges when striving to achieve greater success in winning global competitions. Today, distributed manufacturing is unforeseeably coming into being due to recent business decentralisation and manufacturing outsourcing. Manufacturers are competing in a dynamic marketplace that demands short response time to changing markets and agility in production. In the 21st century, manufacturing is gradually shifting to a distributed environment with increasing dynamism. In order to win a competition, locally or globally, customer satisfaction is treated with priority. This leads to mass customisation and even more complex manufacturing processes, from shop floors to every level along manufacturing supply chains. At the same time, outsourcing has forged a multi-tier supplier structure with numerous small-- medium-sized enterprises involved, where highly-mixed products in small batch sizes are handled simultaneously in job-shop operations.

Manufacturing has been one of the key areas that support and influence a nation’s economy since the 18th century. Being the primary driving force in economic growth, manufacturing constantly serves as the foundation of and contributes to other industries. In the past centuries, manufacturing has contributed to the modern civilisation and created momentum that is continuously driving today’s economy. Despite various revolutionary changes and innovations in the 20th century that contributed to manufacturing advancements, we are facing new challenges when striving to achieve greater success in winning global competitions. Machines and robots, as the constituent components in manufacturing, have contributed significantly to the success of advanced manufacturing. After evolving from the initial mechanisation era where mechanical devices were created to replace human labours to the later automation era where control devices were invented to replace human operations, the history of machines has now entered into the modern era of autonomisation where intelligent devices are being developed in an attempt to eventually replace human decision making. While machines are becoming more and more intelligent through integration with new technologies including sensors, controls, computers and even the Internet, machine structures and theories have also advanced, most noticeably in the area of parallel kinematic machines and micro machines.

Collaborative design has attracted much attention in the research community in recent years. With increasingly decentralized manufacturing systems and processes, more collaborative approaches and systems are needed to support distributed manufacturing operations. "Collaborative Design and Planning for Digital Manufacturing" presents a focused collection of quality chapters on the state-of-the-art research efforts in the area of collaborative design and planning, as well as their practical applications towards digital manufacturing."Collaborative Design and Planning for Digital Manufacturing" provides both a broad-based review of the key areas of research in digital manufacturing, and an in-depth treatment of particular methodologies and systems, from collaborative design to distributed planning, monitoring and control. Recent development and innovations in this area provide a pool of focused research efforts, relevant to a wide readership from academic researchers to practicing engineers.

This book gathers the proceedings of the 5th International Conference on the Industry 4.0 Model for Advanced Manufacturing (AMP 2020), held in Belgrade, Serbia, on 1–4 June 2020.

This book gathers the proceedings of the 5th International Conference on the Industry 4.0 Model for Advanced Manufacturing (AMP 2020), held in Belgrade, Serbia, on 1–4 June 2020.

This book presents state-of-the-art research, challenges and solutions in the area of human–robot collaboration (HRC) in manufacturing. It enables readers to better understand the dynamic behaviour of manufacturing processes, and gives more insight into on-demand adaptive control techniques for industrial robots.With increasing complexity and dynamism in today’s manufacturing practice, more precise, robust and practical approaches are needed to support real-time shop-floor operations. This book presents a collection of recent developments and innovations in this area, relying on a wide range of research efforts.The book is divided into five parts. The first part presents a broad-based review of the key areas of HRC, establishing a common ground of understanding in key aspects. Subsequent chapters focus on selected areas of HRC subject to intense recent interest. The second part discusses human safety within HRC. The third, fourth and fifth parts provide in-depth viewsof relevant methodologies and algorithms. Discussing dynamic planning and monitoring, adaptive control and multi-modal decision making, the latter parts facilitate a better understanding of HRC in real situations.The balance between scope and depth, and theory and applications, means this book appeals to a wide readership, including academic researchers, graduate students, practicing engineers, and those within a variety of roles in manufacturing sectors.

This book presents state-of-the-art research, challenges and solutions in the area of human–robot collaboration (HRC) in manufacturing. It enables readers to better understand the dynamic behaviour of manufacturing processes, and gives more insight into on-demand adaptive control techniques for industrial robots.With increasing complexity and dynamism in today’s manufacturing practice, more precise, robust and practical approaches are needed to support real-time shop-floor operations. This book presents a collection of recent developments and innovations in this area, relying on a wide range of research efforts.The book is divided into five parts. The first part presents a broad-based review of the key areas of HRC, establishing a common ground of understanding in key aspects. Subsequent chapters focus on selected areas of HRC subject to intense recent interest. The second part discusses human safety within HRC. The third, fourth and fifth parts provide in-depth viewsof relevant methodologies and algorithms. Discussing dynamic planning and monitoring, adaptive control and multi-modal decision making, the latter parts facilitate a better understanding of HRC in real situations.The balance between scope and depth, and theory and applications, means this book appeals to a wide readership, including academic researchers, graduate students, practicing engineers, and those within a variety of roles in manufacturing sectors.

This book presents a set of innovative solutions to human-centric manufacturing systems, offering critical insights and comprehensive application guidelines for understanding how to realize human-centric smart manufacturing by exerting its power and influence towards Industry 5.0.While human-centric manufacturing possesses a substantial and growing body of knowledge, there are distinct research gaps that are not sufficiently addressed. With the development of enabling technologies, it is necessary to propose more precise, robust, and practical approaches in support of smart manufacturing towards Industry 5.0. As a response to the new research opportunities, this book presents and highlights the latest development on applying advanced techniques in human-centric manufacturing. The book will be of interest to a broad readership, from academic researchers to practicing engineers

This book presents state-of-the-art research, challenges and solutions in the area of cloud-based cyber-physical systems (CPS) used in manufacturing.

This book presents state-of-the-art research, challenges and solutions in the area of cloud-based cyber-physical systems (CPS) used in manufacturing.

The book focuses on visual object tracking systems and approaches based on correlation filter and deep learning.

The book focuses on visual object tracking systems and approaches based on correlation filter and deep learning.