Lisa Bain – författare
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31 produkter
Sex Differences in Brain Disorders
Emerging Transcriptomic Evidence: Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2021
646 kr
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Accumulating evidence gathered over the past three decades has demonstrated a biological basis for differences between men and women with respect to clinical features and treatment responses to several neuropsychiatric, neurodevelopmental, and neurodegenerative disorders. Dramatic sex differences …
From Molecular Insights to Patient Stratification for Neurological and Psychiatric Disorders
Proceedings of a Workshop
Av and Medicine National Academies of Sciences, Engineering, Health and Medicine Division m. fl.
Häftad, 2022
247 kr
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While significant progress has been seen in fields such as cardiovascular medicine and cancer in improving patient stratification and developing targeted drugs based on genetic findings, progress continues to lag for neuropsychiatric disorders. To address this issue, the National Academies of …
From Molecular Insights to Patient Stratification for Neurological and Psychiatric Disorders
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2022
367 kr
Lägg i varukorg
While significant progress has been seen in fields such as cardiovascular medicine and cancer in improving patient stratification and developing targeted drugs based on genetic findings, progress continues to lag for neuropsychiatric disorders. To address this issue, the National Academies of …
Enabling Discovery, Development, and Translation of Treatments for Cognitive Dysfunction in Depression
Workshop Summary
Av and Medicine National Academies of Sciences, Engineering, Institute of Medicine m. fl.
Häftad, 2015
736 kr
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Major depressive disorder (MDD) is recognized worldwide as a major cause of disability, morbidity, and mortality. According to the World Health Organization, unipolar depressive disorders affect more than 150 million people around the world and represent the leading cause of years lost due to …
Enabling Discovery, Development, and Translation of Treatments for Cognitive Dysfunction in Depression
Workshop Summary
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2015
660 kr
Lägg i varukorg
Major depressive disorder (MDD) is recognized worldwide as a major cause of disability, morbidity, and mortality. According to the World Health Organization, unipolar depressive disorders affect more than 150 million people around the world and represent the leading cause of years lost due to …
Non-Invasive Neuromodulation of the Central Nervous System
Opportunities and Challenges: Workshop Summary
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2015
607 kr
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Based on advances in biotechnology and neuroscience, non-invasive neuromodulation devices are poised to gain clinical importance in the coming years and to be of increasing interest to patients, clinicians,health systems, payers, and industry. Evidence suggests that both therapeutic and …
Assessing the Impact of Applications of Digital Health Records on Alzheimer's Disease Research
Workshop Summary
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2016
642 kr
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Health information technology is providing patients, clinicians, and researchers with access to data that will enable novel approaches to science and medicine. Digital health records (DHRs) are capable of being shared across different health care settings for the examination of possible trends and …
Neuroscience Trials of the Future
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2016
660 kr
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On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine''s Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical …
Developing Multimodal Therapies for Brain Disorders
Proceedings of a Workshop
Av and Medicine National Academies of Sciences, Engineering, Health and Medicine Division m. fl.
Häftad, 2017
460 kr
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Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potentiala "and perhaps essentiala "ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying …
Developing Multimodal Therapies for Brain Disorders
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2017
678 kr
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Multimodal therapy approaches that combine interventions aimed at different aspects of disease are emerging as potential—and perhaps essential—ways to enhance clinical outcomes for patients with psychiatric and neurological disorders. In order to examine the general principles underlying multimodal …
Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders
Proceedings of a Workshop
Av and Medicine National Academies of Sciences, Engineering, Health and Medicine Division m. fl.
Häftad, 2017
536 kr
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Compared with other disease areas, central nervous system (CNS) disorders have had the highest failure rate for new compounds in advanced clinical trials. Most CNS drugs fail because of efficacy, and the core issue underlying these problems is a poor understanding of disease biology. Concern about …
Therapeutic Development in the Absence of Predictive Animal Models of Nervous System Disorders
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2017
803 kr
Lägg i varukorg
Compared with other disease areas, central nervous system (CNS) disorders have had the highest failure rate for new compounds in advanced clinical trials. Most CNS drugs fail because of efficacy, and the core issue underlying these problems is a poor understanding of disease biology. Concern about …
Biomarkers of Neuroinflammation
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2018
731 kr
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Neuroinflammation is a burgeoning area of interest in academia and biopharma, with a broadly acknowledged role in many central nervous system (CNS) disorders. However, there is little agreement on the pathophysiological mechanisms that underlie the manifestations of neuroinflammation in the CNS …
Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Blood-?Brain Barrier
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2018
803 kr
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Despite substantial advances in developing treatments for the serious illnesses that affect people worldwide, there remains a tremendous unmet need in the treatment of complex neurologic diseases, including neuropsychiatric and neurodegenerative disorders. Chief among the challenges that have …
Advancing Therapeutic Development for Pain and Opioid Use Disorders Through Public-Private Partnerships
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2018
660 kr
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Chronic pain is one of the most prevalent, costly, and disabling health conditions in the United States. Estimates show that more than 11 percent of the American population suffer from chronic pain, yet the federal pain research investment has been minimal. In parallel with a gradual increased …
Neuroforensics
Exploring the Legal Implications of Emerging Neurotechnologies: Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2018
622 kr
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Technological advances in noninvasive neuroimaging, neurophysiology, genome sequencing, and other methods together with rapid progress in computational and statistical methods and data storage have facilitated large-scale collection of human genomic, cognitive, behavioral, and brain-based data. The …
Harnessing Mobile Devices for Nervous System Disorders
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2018
874 kr
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The critical importance of using mobile technology is clear to anyone in the health professions, particularly those who treat people with central nervous system (CNS) disorders. To explore current developments and opportunities for using mobile technology to advance research and treatment of CNS …
Transgenic Neuroscience Research
Exploring the Scientific Opportunities Afforded by New Nonhuman Primate Models: Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2019
874 kr
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To examine the promise, concerns, and challenges related to neuroscience research using genetically modified nonhuman primates, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop on October 4, 2018, bringing together an international group of experts and …
Role of Nonpharmacological Approaches to Pain Management
Proceedings of a Workshop
Av and Medicine National Academies of Sciences, Engineering, Health and Medicine Division m. fl.
Häftad, 2019
475 kr
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Pain is a leading cause of disability globally. The dramatic increase in opioid prescriptions within the past decade in the United States has contributed to the opioid epidemic the country currently faces, magnifying the need for longer term solutions to treat pain. The substantial burden of pain …
Role of Nonpharmacological Approaches to Pain Management
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Global Forum on Innovation in Health Professional Education m. fl.
E-bok, 2019
731 kr
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Pain is a leading cause of disability globally. The dramatic increase in opioid prescriptions within the past decade in the United States has contributed to the opioid epidemic the country currently faces, magnifying the need for longer term solutions to treat pain. The substantial burden of pain …
Advancing Gene-Targeted Therapies for Central Nervous System Disorders
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2019
981 kr
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On April 23 and 24, 2019 the Forum on Neuroscience and Nervous System Disorders convened a workshop titled "Advancing Gene-Targeted Therapies for Central Nervous System Disorders" in Washington, DC. This public workshop brought together experts and key stakeholders from academia, government, …
Neuroscience Data in the Cloud
Opportunities and Challenges: Proceedings of a Workshop
Av and Medicine National Academies of Sciences, Engineering, Health and Medicine Division m. fl.
Häftad, 2020
435 kr
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The cloud model of data sharing has led to a vast increase in the quantity and complexity of data and expanded access to these data, which has attracted many more researchers, enabled multi-national neuroscience collaborations, and facilitated the development of many new tools. Yet, the cloud model …
Neuroscience Data in the Cloud
Opportunities and Challenges: Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2020
641 kr
Lägg i varukorg
The cloud model of data sharing has led to a vast increase in the quantity and complexity of data and expanded access to these data, which has attracted many more researchers, enabled multi-national neuroscience collaborations, and facilitated the development of many new tools. Yet, the cloud model …
Environmental Neuroscience
Advancing the Understanding of How Chemical Exposures Impact Brain Health and Disease: Proceedings of a Workshop
Av and Medicine National Academies of Sciences, Engineering, Division on Earth and Life Studies m. fl.
Häftad, 2020
722 kr
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Humans are potentially exposed to more than 80,000 toxic chemicals in the environment, yet their impacts on brain health and disease are not well understood. The sheer number of these chemicals has overwhelmed the ability to determine their individual toxicity, much less potential interactive …
Environmental Neuroscience
Advancing the Understanding of How Chemical Exposures Impact Brain Health and Disease: Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2020
641 kr
Lägg i varukorg
Humans are potentially exposed to more than 80,000 toxic chemicals in the environment, yet their impacts on brain health and disease are not well understood. The sheer number of these chemicals has overwhelmed the ability to determine their individual toxicity, much less potential interactive …
Novel Molecular Targets for Mood Disorders and Psychosis
Proceedings of a Workshop
Av and Medicine National Academies of Sciences, Engineering, Health and Medicine Division m. fl.
Häftad, 2021
722 kr
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Mood disorders - including depression and bipolar disorder - are common, disabling, and potentially lethal disorders, characterized by a shortened lifespan from comorbid medical illness and rising suicide rates. Medications for these conditions have been shown to be insufficiently effective in the …
Novel Molecular Targets for Mood Disorders and Psychosis
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2021
660 kr
Lägg i varukorg
Mood disorders - including depression and bipolar disorder - are common, disabling, and potentially lethal disorders, characterized by a shortened lifespan from comorbid medical illness and rising suicide rates. Medications for these conditions have been shown to be insufficiently effective in the …
Methadone Treatment for Opioid Use Disorder
Improving Access Through Regulatory and Legal Change: Proceedings of a Workshop
Av Board on Health Sciences Policy, Board on Health Care Services m. fl.
E-bok, 2022
367 kr
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Methadone is a Food and Drug Administration- (FDA-) approved medication for treating opioid use disorder (OUD), a chronic brain disease that affects more than 2.7 million people in the United States aged 12 and older. Despite its effectiveness in saving lives, many barriers impede access to, …
Exploring Psychedelics and Entactogens as Treatments for Psychiatric Disorders
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2022
225 kr
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Psychiatric illnesses - such as major depressive disorder, anxiety disorder, substance use disorder, and posttraumatic stress disorder (PTSD) - are widely prevalent and represent a substantial health burden worldwide. Yet, conventional medications for mental illnesses often fail to provide relief …
Exploring Sleep Disturbance in Central Nervous System Disorders
Proceedings of a Workshop
Av Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy m. fl.
E-bok, 2023
321 kr
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Chronic sleep disorders affect one in five Americans, and sleep deprivation costs significant U.S. GDP loss annually. Despite the indisputable biological importance of sleep, much remains unknown about underlying mechanisms. The National Academies Forum on Neuroscience and Nervous System Disorders …
