Ming Hu – författare

Sustainability has become a driver of innovation in the built environment, but the affordability of sustainable building remains a significant challenge. This book takes a critical view of the real cost of green building. It provides readers with a non-biased evaluation based on empirical construction cost data and sheds light on the affordability of sustainable buildings.

Chapters are presented in three parts. The first part lays the foundation to demystify the perception of green buildings being expensive to construct by providing empirical evidence that green buildings, even net-zero buildings, are not necessarily more expensive to build than conventional buildings. The second part presents empirical evidence, common misperceptions of a higher green building construction cost are debunked. The author offers a new framework to explain the construction cost drivers and differences of sustainable buildings: the project characteristics and project team characteristics (human factors). The third part directs the readers’ attention to the important role that human factors play in controlling and reducing construction costs, with a focus on the project design team. A lack of skills, expertise, and experience during the design phase is likely to be the biggest contributor to higher construction costs. Empirical analysis, case studies on LEED-certified buildings, and interviews with project teams are used to present a pathway to more affordable green building at the end.

This will be a crucial resource for students and professionals in architecture, engineering, construction management, and planning and energy policy.

Sustainability has become a driver of innovation in the built environment, but the affordability of sustainable building remains a significant challenge. This book takes a critical view of the real cost of green building. It provides readers with a non-biased evaluation based on empirical construction cost data and sheds light on the affordability of sustainable buildings.

Chapters are presented in three parts. The first part lays the foundation to demystify the perception of green buildings being expensive to construct by providing empirical evidence that green buildings, even net-zero buildings, are not necessarily more expensive to build than conventional buildings. The second part presents empirical evidence, common misperceptions of a higher green building construction cost are debunked. The author offers a new framework to explain the construction cost drivers and differences of sustainable buildings: the project characteristics and project team characteristics (human factors). The third part directs the readers’ attention to the important role that human factors play in controlling and reducing construction costs, with a focus on the project design team. A lack of skills, expertise, and experience during the design phase is likely to be the biggest contributor to higher construction costs. Empirical analysis, case studies on LEED-certified buildings, and interviews with project teams are used to present a pathway to more affordable green building at the end.

This will be a crucial resource for students and professionals in architecture, engineering, construction management, and planning and energy policy.

Understand and assess the design, delivery, and efficacy of orally administered drugs

A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help chemists, biologists, life science researchers, pharmaceutical scientists, pharmacologists, clinicians, and graduate and students become familiar with the fundamentals and practices of the science of oral bioavailability.

The difference in rate and extent between a drug taken orally and the actual amount of a drug reaching the circulatory system, oral bioavailability is an essential parameter for determining the efficacy and adverse effects of new and developing medications, as well as finding an optimal dosing regimen.

This book provides a much-needed one-stop resource to help readers better understand and appreciate the many facets and complex problems of oral bioavailability, including the basic barriers to oral bioavailability, the methods used to determine relevant parameters, and the challenges of drug delivery.

In addition, this comprehensive book discusses biological and physicochemical methods for improving bioavailability, integrates physicochemistry with physiology and molecular biology, and includes several state-of-the-art technologies and approaches—Caco-2 cell culture model, MDCK, and other related cell culture models—which are used to study the science of oral bioavailability.

Understand and assess the design, delivery, and efficacy of orally administered drugs

A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help chemists, biologists, life science researchers, pharmaceutical scientists, pharmacologists, clinicians, and graduate and students become familiar with the fundamentals and practices of the science of oral bioavailability.

The difference in rate and extent between a drug taken orally and the actual amount of a drug reaching the circulatory system, oral bioavailability is an essential parameter for determining the efficacy and adverse effects of new and developing medications, as well as finding an optimal dosing regimen.

This book provides a much-needed one-stop resource to help readers better understand and appreciate the many facets and complex problems of oral bioavailability, including the basic barriers to oral bioavailability, the methods used to determine relevant parameters, and the challenges of drug delivery.

In addition, this comprehensive book discusses biological and physicochemical methods for improving bioavailability, integrates physicochemistry with physiology and molecular biology, and includes several state-of-the-art technologies and approaches—Caco-2 cell culture model, MDCK, and other related cell culture models—which are used to study the science of oral bioavailability.

Improve the performance and viability of newly-developed and approved drugs with this crucial guide

Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user’s circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development.

Oral Bioavailability and Drug Delivery provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research.

Oral Bioavailability and Drug Delivery readers will also find:

Oral Bioavailability and Drug Delivery is ideal for pharmaceutical and biotechnology scientists working in drug discovery and development; researchers in chemistry, biology, pharmacology, immunology, neuroscience, and other related fields; and graduate courses in drug development and delivery.

Improve the performance and viability of newly-developed and approved drugs with this crucial guide

Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user’s circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development.

Oral Bioavailability and Drug Delivery provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research.

Oral Bioavailability and Drug Delivery readers will also find:

Oral Bioavailability and Drug Delivery is ideal for pharmaceutical and biotechnology scientists working in drug discovery and development; researchers in chemistry, biology, pharmacology, immunology, neuroscience, and other related fields; and graduate courses in drug development and delivery.

What do we mean by net zero energy? Zero operating energy? Zero energy costs? Zero emissions? There is no one answer: approaches to net zero building vary widely across the globe and are influenced by different environmental and cultural contexts.

Net Zero Energy Building: Predicted and Unintended Consequences presents a comprehensive overview of variations in ''net zero'' building practices. Drawing on examples from countries such as the United States, United Kingdom, Germany, Japan, Hong Kong, and China, Ming Hu examines diverse approaches to net zero and reveals their intended and unintended consequences.

Existing approaches often focus on operating energy: how to make buildings more efficient by reducing the energy consumed by climate control, lighting, and appliances. Hu goes beyond this by analyzing overall energy consumption and environmental impact across the entire life cycle of a building—ranging from the manufacture of building materials to transportation, renovation, and demolition. Is net zero building still achievable once we look at these factors?

With clear implications for future practice, this is key reading for professionals in building design, architecture, and construction, as well as students on sustainable and green architecture courses.

What do we mean by net zero energy? Zero operating energy? Zero energy costs? Zero emissions? There is no one answer: approaches to net zero building vary widely across the globe and are influenced by different environmental and cultural contexts.

Net Zero Energy Building: Predicted and Unintended Consequences presents a comprehensive overview of variations in ''net zero'' building practices. Drawing on examples from countries such as the United States, United Kingdom, Germany, Japan, Hong Kong, and China, Ming Hu examines diverse approaches to net zero and reveals their intended and unintended consequences.

Existing approaches often focus on operating energy: how to make buildings more efficient by reducing the energy consumed by climate control, lighting, and appliances. Hu goes beyond this by analyzing overall energy consumption and environmental impact across the entire life cycle of a building—ranging from the manufacture of building materials to transportation, renovation, and demolition. Is net zero building still achievable once we look at these factors?

With clear implications for future practice, this is key reading for professionals in building design, architecture, and construction, as well as students on sustainable and green architecture courses.

This edited book examines the challenges and opportunities arising from today’s sharing economy from an operations management perspective.  Individual chapter authors present state-of-the-art research that examines the general impact of sharing economy on production and consumption; the intermediary role of a sharing platform; crowdsourcing management; and context-based operational problems.

Sharing economy refers to a market model that enables and facilitates the sharing of access to goods and services. For example, Uber allows riders to share a car. Airbnb allows homeowners to share their extra rooms with renters. Groupon crowdsources demands, enabling customers to share the benefit of discounted goods and services, whereas Kickstarter crowdsources funds, enabling backers to fund a project jointly. Unlike the classic supply chain settings in which a firm makes inventory and supply decisions, in sharing economy, supply is crowdsourced and can be modulated by a platform.The matching-supply-with-demand process in a sharing economy requires novel perspectives and tools to address challenges and identify opportunities.

The book is comprised of 20 chapters that are divided into four parts.  The first part explores the general impact of sharing economy on the production, consumption, and society.  The second part explores the intermediary role of a sharing platform that matches crowdsourced supply with demand.  The third part investigates the crowdsourcing management on a sharing platform, and the fourth part is dedicated to context-based operational problems of popular sharing economy applications.

“While sharing economy is becoming omnipresence, the operations management (OM) research community has begun to explore and examine different business models in the transportation, healthcare, financial, accommodation, and sourcing sectors. This book presents a collection of the state-of-the-art research work conducted by a group of world-leading OM researchers in this area. Not only does this book cover a wide range of business models arising from the sharing economy, but it also showcases different modeling frameworks and research methods that cannot be missed. Ultimately, this book is a tour de force – informative and insightful!”

Christopher S. Tang Distinguished Professor and Edward Carter Chair in Business Administration UCLA Anderson School of Management

Smart Technologies and Design for Healthy Built Environment connects smart technology to a healthy built environmentthat builds upon the sustainable building movement.It provides an overall summary of the state-of-the-art technologies that are applied in the built environment. The book covers a broad spectrum of smart technology categories ranging from dynamic operability, energy efficiency, self-regulating and self-learning systems, and responsive systems. The foreseeable challenges that are associated with smart technologies are discussed and outlined in the book.

Firstly, this book provides a snapshot of state-of-the-art smart technologies being applied in the built environment. It covers a broad spectrum of smart technology categories, ranging from dynamic operability, energy efficiency, self-regulating and self-learning systems, to responsive systems. Secondly, this book provides in-depth analysis of the four primary components of health (biological, physical, physiological and psychological); their effects on wellbeing and cognitive performance are introduced as well. Thirdly, it connects smart technologies to those health-influencing factors by reviewing three completed smart building projects. This book can also serve as a basis for education and discussion among professionals and students of diverse backgrounds who are interested in smart technologies, smart building, and healthy building.

Smart Technologies and Design for Healthy Built Environment serves as the basis for education and discussions among professionals and students who are interested in smart technologies, smart building and healthy building, as it bridges the gap between smart technologies and a healthy built environment. The book also provides a foundation for anyone who is interested in the impact of smart technology on the health of built environment.