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This book discusses the most significant recent advances in oncological molecular imaging, covering the full spectrum from basic and preclinical research to clinical practice. The content is divided into five sections, the first of which is devoted to standardized and emerging technologies and probe designs for different modalities, such as PET, SPECT, optical and optoacoustic imaging, ultrasound, CT, and MRI. The second section focuses on multiscale preclinical applications ranging from advanced microscopy and mass spectroscopy to whole-body imaging. In the third section, various clinical applications are presented, including image-guided surgery and the radiomic analysis of multiple imaging features. The final two sections are dedicated to the emerging, crucial role that molecular imaging can play in the planning and monitoring of external and internal radiotherapy, and to future challenges and prospects in multimodality imaging. Given its scope, the handbook will benefit allreaders who are interested in the revolution in diagnostic and therapeutic oncology that is now being brought about by molecular imaging.
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Advanced Solutions to Acquire Disease-Specific Biomarkers - Technologies and Preclinical Applications
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Advanced Solutions to Acquire Disease-Specific Biomarkers - Clinical Applications
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The essentials of PET-CT fusion technology in one practical, comprehensive volume
Written by a multidisciplinary team of experts in radiology and nuclear medicine, this lavishly illustrated handbook presents an evidence-based look at the most up-to-date image-fusion technology in clinical use today. The authors combine multislice spiral CT anatomic images with specific sensitive molecular images of PET in one examination to give readers a full understanding of this evolving technology.
The book places special emphasis on tumor imaging, with additional chapters on the imaging of inflammatory, cardiovascular, and neurodegenerative diseases. Leading clinicians provide systematic discussion of patient preparation, recommendations for imaging protocols for specific indications, and examination techniques such as slice orientation and positioning. To prepare the reader for daily practice, CT and PET-CT scans appear throughout the text side-by-side with explanations of their interpretation.
Highlights:
616 high-quality images - including 175 in full color - complement the text Easy-to-reference textboxes and sidebars present key concepts, pearls, and pitfalls Detailed summaries at the end of each chapter facilitate rapid review Carefully selected suggestions for further reading at the end of each section A comprehensive glossary of frequently used terms and a list of common abbreviationsIdeal for practicing radiologists, radiologic technologists, and radiology residents, PET-CT Hybrid Imaging is an essential reference for anyone who needs to quickly compare and interpret PET-CT images. It is also an excellent preparation tool for Board examinations.
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The impact of molecular imaging on diagnostics, therapy, and follow-up in oncology is increasing steadily. Many innovative molecular imaging probes have already entered clinical practice, and there is no doubt that the future emphasis will be on multimodality imaging in which morphological, functional, and molecular imaging techniques are combined in a single clinical investigation. This handbook addresses all aspects of molecular imaging in oncology, from basic research to clinical applications. The first section is devoted to technology and probe design, and examines a variety of PET and SPECT tracers as well as multimodality probes. Preclinical studies are then discussed in detail, with particular attention to multimodality imaging. In the third section, diverse clinical applications are presented, and the book closes by looking at future challenges. This handbook will be of value to all who are interested in the revolution in diagnostic oncology that is being brought about by molecular imaging.
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