Owen P. Ward - Böcker

Methods for processing of biological materials into useful products represent essential core manufacturing activities of the food, chemical and pharmaceutical industries. On the one hand the techniques involved include well established process engineering methodologies such as mixing, heat transfer, size modification and a variety of separatIon and fermentation procedures. In addition, new bioprocessing practices arising from the exciting recent advances in biotech­ nology, including innovative fermentation cell culture and enzyme based operations, are rapidly extending the frontiers of bioprocessing. These develop­ ments are resulting in the introduction to the market place of an awesome range of novel biological products having unique applications. Indeed, the United States Office of Technology Assessment· has concluded that 'competitive advantage in areas related to biotechnology may depend as much on developments in bioprocess engineering as on innovations in genetics, immunology and other areas of basic science'. Advances in analytical instrumentation, computerization and process automation are playing an important role in process control and optimization and in the maintenance of product quality and consistency characteristics. Bioprocessing represents the industrial practice of biotechnology and is multidisciplinary in nature, integrating the biological, chemical and engineering sciences. This book discusses the individual unit operations involved and describes a wide variety of important industrial bioprocesses. I am very grateful to Sanjay Thakur who assisted me in the collection of material for this book.

Methods for processing of biological materials into useful products represent essential core manufacturing activities of the food, chemical and pharmaceutical industries. On the one hand the techniques involved include well established process engineering methodologies such as mixing, heat transfer, size modification and a variety of separatIon and fermentation procedures. In addition, new bioprocessing practices arising from the exciting recent advances in biotech­ nology, including innovative fermentation cell culture and enzyme based operations, are rapidly extending the frontiers of bioprocessing. These develop­ ments are resulting in the introduction to the market place of an awesome range of novel biological products having unique applications. Indeed, the United States Office of Technology Assessment· has concluded that 'competitive advantage in areas related to biotechnology may depend as much on developments in bioprocess engineering as on innovations in genetics, immunology and other areas of basic science'. Advances in analytical instrumentation, computerization and process automation are playing an important role in process control and optimization and in the maintenance of product quality and consistency characteristics. Bioprocessing represents the industrial practice of biotechnology and is multidisciplinary in nature, integrating the biological, chemical and engineering sciences. This book discusses the individual unit operations involved and describes a wide variety of important industrial bioprocesses. I am very grateful to Sanjay Thakur who assisted me in the collection of material for this book.

The production of a vast array of chemicals, especially petroleum compounds during the last century, has caused a serious deterioration in environmental quality. In this context, one major threat is posed by the continually expanding areas of contaminated soils and sediments.Biotechnological methods based on the biodegradation of environmental pollutants or phytoremediation of persistent organic contaminants and metals are being developed. Bioremediation has been used successfully to remediate many petroleum-contaminated sites. However, there are as yet no commercial technologies commonly used to remediate the most recalcitrant contaminants, such as explosives, pesticides and metallic pollutants. Nevertheless, bioremediation is a rapidly advancing field and new bio-based remedial technologies are continuing to emerge. For this volume, a number of experts from universities, government laboratories and industry, have contributed chapters on innovative methods in bioremediation and phytoremediation.

In this volume, experts from universities, government labs and industry share their findings on the microbiological, biochemical and molecular aspects of biodegradation and bioremediation. The text covers numerous topics, including: bioavailability, biodegradation of various pollutants, microbial community dynamics, properties and engineering of important biocatalysts, and methods for monitoring bioremediation processes. Microbial processes are environmentally compatible and can be integrated with non-biological processes to detoxify, degrade and immobilize environmental contaminants.

Mikroorganismen sind eine wichtige Hilfe bei der Herstellung von Industriechemikalien, Lebensmittelprodukten, Brennmaterialien und Arzneimitteln durch Fermentation (Kultivierung). Obwohl dieser grundlegende Prozess bereits seit vielen tausend Jahren genutzt wird, sind in den letzten zwei Jahrzehnten immense Fortschritte in der Technologie der Fermentation gemacht worden und eine Vielfalt neuer und verbesserter Produkte hergestellt worden. Das vorliegende Buch gibt eine vollstandige, aktuelle Einfuhrung in die Fermentationstechnologie, wobei das Schwergewicht auf industriellen Anwendungen und Problemstellungen liegt. Zum Abschluss bringt der Autor noch ein Kapitel uber den Einsatz von Mikroorganismen bei Abfall- und Abwasserbehandlungen. Dieses Buch vermittelt sowohl dem Biotechnologiestudenten als auch dem bereits im Beruf stehenden Biotechnologen eine solide Basis.

Bioremediation is a rapidly advancing field and the technology has been applied successfully to remediate many contaminated sites. The goal of every soil remediation method is to enhance the degradation, transformation, or detoxification of pollutants and to protect, maintain and sustain environmental quality.Advances in our understanding of the ecology of microbial communities capable of breaking down various pollutants and the molecular and biochemical mechanisms by which biodegradation occurs have helped us in developing practical soil bioremediation strategies. Chapters dealing with the application of biological methods to soil remediation are contributed from experts – authorities in the area of environmental science including microbiology and molecular biology – from academic institutions and industry.

The production of a vast array of chemicals, especially petroleum compounds during the last century, has caused a serious deterioration in environmental quality. In this context, one major threat is posed by the continually expanding areas of contaminated soils and sediments. Biotechnological methods based on the biodegradation of environmental pollutants or phytoremediation of persistent organic contaminants and metals are being developed. Bioremediation has been used successfully to remediate many petroleum-contaminated sites. However, there are as yet no commercial technologies commonly used to remediate the most recalcitrant contaminants, such as explosives, pesticides and metallic pollutants. Nevertheless, bioremediation is a rapidly advancing field and new bio-based remedial technologies are continuing to emerge. For this volume, a number of experts from universities, government laboratories and industry, have contributed chapters on innovative methods in bioremediation and phytoremediation.

In this volume, experts from universities, government labs and industry share their findings on the microbiological, biochemical and molecular aspects of biodegradation and bioremediation. The text covers numerous topics, including: bioavailability, biodegradation of various pollutants, microbial community dynamics, properties and engineering of important biocatalysts, and methods for monitoring bioremediation processes. Microbial processes are environmentally compatible and can be integrated with non-biological processes to detoxify, degrade and immobilize environmental contaminants.

Bioremediation is a rapidly advancing field and the technology has been applied successfully to remediate many contaminated sites. The goal of every soil remediation method is to enhance the degradation, transformation, or detoxification of pollutants and to protect, maintain and sustain environmental quality.Advances in our understanding of the ecology of microbial communities capable of breaking down various pollutants and the molecular and biochemical mechanisms by which biodegradation occurs have helped us in developing practical soil bioremediation strategies. Chapters dealing with the application of biological methods to soil remediation are contributed from experts – authorities in the area of environmental science including microbiology and molecular biology – from academic institutions and industry.