Paul Davis – författare

Anti-angiogenesis Strategies in Cancer Therapeutics provides a detailed look at the current status and future directions in the discovery and development of novel anti-angiogenesis strategies in oncology. This book highlights the different mechanisms involved in the modulation of angiogenesis, including inflammation, thrombosis, and microRNA, and shows how nanotechnology can further enhance the potential of existing and new anti-angiogenesis approaches.

Written for industry scientists, researchers, oncologists, hematologists, and professors and students in the field, this comprehensive book covers all aspects of anti-angiogenesis strategies and their differences.

Covers important preclinical models and clinical trials in the discovery and development of novel anti-angiogenesis agents Reviews FDA-approved anti-angiogenesis agents Illustrates the value of nanotechnology in improving the utility of anti-angiogenesis agents Offers insight into the development of novel anti-angiogenesis agents and future direction in this area

In Great Commanders, Davis turns his attention to military leaders from throughout history who stand out for their abilities - indeed, individuals who were destined for success or even born to command, challenging the prevailing view that movements, rather than individuals, have determined the progression of history. In short, this is unapologetically Great Man history. Each chapter opens with a brief biography that reveals or outlines the subject's character, followed by an overview of the methods of warfare of his time. A concise overview of each subject's military career leads to a more in-depth look at the battles that reveal precisely how each commander was able to achieve victory, often against great odds. Finally, Davis analyzes each individual's contribution to tactical warfare and offers an assessment of how his personality shaped his leadership style.

Joseph Addison: Tercentenary Essays is a collection of fifteen essays by a team of internationally recognized experts specially commissioned to commemorate the three hundredth anniversary of Addison's death in 2019. Almost exclusively known now as the inventor and main author of The Spectator, probably the most widely read and imitated prose work of the eighteenth century, Addison also produced important and influential work across a broad gamut of other literary modes--poems, verse translations, literary criticism, periodical journalism, drama, opera, travel writing. Much of this work is little known nowadays even in specialist academic circles; Addison is often described as the most neglected of the eighteenth century's major writers. This volume is the first collection to address the full range and variety of Addison's career and writings. Its fifteen chapters fall into three groupings: the first set study Addison's work in modes other than the literary periodical (poetry, translation, travel writing, drama); the second set address The Spectator from a variety of disciplinary perspectives (literary-critical, sociological and political, bibliographical); and the final set explore Addison's reception within several cultural spheres (philosophy, horticulture, art history), by individual writers or across larger historical periods (the Romantic age, the Victorian age), and in Britain and Europe, especially France. The volume provides an overdue and appropriately diverse memorial to one of the dominant men of letters of the Georgian era.

Between the Civil War and the early decades of the eighteenth century, English poets of the first rank devoted more of their time and creative energies to translating than they had ever done before or have ever done since. Paul Davis's Translation and the Poet's Life is the first study to range across the entirety of this golden age of poetic translation in England, taking as its organizing principle and object of inquiry the significances of translating itself as a distinctive mode of imaginative conduct. Composed of case studies of the five leading poet-translators of the age - John Denham, Henry Vaughan, Abraham Cowley, John Dryden, and Alexander Pope - it explores the part translation played in their lives as poets and thence in modelling 'the poet's life' during what was a period of transition between early-modern and modern constructions of it. The argumentative method of the book is metaphorical. Each chapter explores the impact on the theory and practice of the poet at issue of a metaphor or group of metaphors broadly current in contemporary translation discourse: in particular, figurations of the translator as an exile, as a child, as a code-breaker, and as a slave; and comparisons of translation to friendship, sexual congress, metamorphosis and trade. The majority of these metaphors were wholly or potentially pejorative: translation remained a controversial practice throughout this period, widely depreciated and stigmatized. Turning translator accordingly forced the five major poets considered in Translation and the Poet's Life to undertake strenuous efforts of self-inquiry and self-presentation; to find new answers to questions integral to their understandings of themselves and their standing in their culture: questions about vocation and career, fame and happiness, responsibility and freedom. Translation and the Poet's Life tells the stories of these personal and public remakings.

'If I by miracle can beThis livelong minute true to thee'Tis all that heav'n allows.'The Earl of Rochester was England's first celebrity poet, a byword for the theatricality, licentiousness, and scepticism of the Restoration age. But his scandalous reputation belies the variety and sophistication of his work: his love poems set new standards not only of sexual explicitness but also of psychological acuity and lyric grace, while his satires broke new ground as much by the refinement of their ironies as in the brutality of their invective. A fascinatingly contradictory figure, Rochester emerges more clearly than ever from this new edition, the first selection of his work in modern spelling to take account of recent revolutionary advances in textual scholarship. It includes only poems now securely attributed to the poet, in texts based not on the posthumous and unreliable printed editions but on the most authoritative manuscripts which circulated in his lifetime. ABOUT THE SERIES: For over 100 years Oxford World's Classics has made available the widest range of literature from around the globe. Each affordable volume reflects Oxford's commitment to scholarship, providing the most accurate text plus a wealth of other valuable features, including expert introductions by leading authorities, helpful notes to clarify the text, up-to-date bibliographies for further study, and much more.

There are a broad variety of sex and gender resonances in sport, from the clash of traditional ideas of femininity and athleticism represented by female athletes, to the culture of homophobia in mainstream male sport. Despite the many sociological and cultural volumes addressing these subjects, this collection is the first to focus on the philosophical writings that they have inspired. The editors have selected twelve of the most thought-provoking philosophical articles on these subjects from the past thirty years, to create a valuable and much needed resource. Written by established experts from all over the world, the essays in this collection cover four major themes:sport and the construction of the female objectification and the sexualization of sport homophobia sex boundaries: obstruction, naturalization and opposition.The book gathers a broad range of philosophical viewpoints on gender in sport into one unique source, subjecting the philosophical origins and characteristics of some of the most controversial topics in sport to rigorous scrutiny. With a balance of male and female contributors from both sides of the Atlantic, and a comprehensive introduction and postscript to contextualize the source material, Philosophical Perspectives on Gender in Sport and Physical Activity is essential reading for all students of the philosophy of sport, sport and gender, and feminist philosophy.

There are a broad variety of sex and gender resonances in sport, from the clash of traditional ideas of femininity and athleticism represented by female athletes, to the culture of homophobia in mainstream male sport. Despite the many sociological and cultural volumes addressing these subjects, this collection is the first to focus on the philosophical writings that they have inspired. The editors have selected twelve of the most thought-provoking philosophical articles on these subjects from the past thirty years, to create a valuable and much needed resource. Written by established experts from all over the world, the essays in this collection cover four major themes:sport and the construction of the female objectification and the sexualization of sport homophobia sex boundaries: obstruction, naturalization and opposition.The book gathers a broad range of philosophical viewpoints on gender in sport into one unique source, subjecting the philosophical origins and characteristics of some of the most controversial topics in sport to rigorous scrutiny. With a balance of male and female contributors from both sides of the Atlantic, and a comprehensive introduction and postscript to contextualize the source material, Philosophical Perspectives on Gender in Sport and Physical Activity is essential reading for all students of the philosophy of sport, sport and gender, and feminist philosophy.

Treating individuals with a substance misuse problem can be challenging, especially if clients present with multiple problems related to the main addiction. Clinicians can feel at a loss as to where to begin, or revert to an attempt to treat underlying problems - ignoring damaging aspects of the substance misuse itself. At times referral to specialists may seem the only responsible way forward. Written by a team of clinical academics in the field of addictions, Cognitive-Behavioural Therapy in the Treatment of Addictions is a ready reference for clinicians that offers a brief, evidence-based, collaborative approach that starts here and now. Client and therapist embark together on a journey to tackle the problem in a practical way. The book includes session tools, worksheets and daily thought records.

This book contains a wealth of new techniques to extend the traditional language-learning activity of dictation. It presents thought-provoking answers to such apparently simple questions as: Who chooses the text? Who dictates? Who corrects? What and how do they correct? The activities range from traditional focuses on spelling and punctuation problems to exercise that emphasize personal attitudes and opinions of both teachers and students. Dictation provides activities suitable for a wide range of levels and ages, example texts for many activities, with permission to copy, opportunities for students to create their own texts, a variety of suggested correction techniques, and suggestions for using dictation in teacher training.

Ways of Doing helps students discover how they do things, both inside and outside the classroom. Based largely on humanistic principles, it over 100 activities designed to encourage students to think, speak and write in English about areas they may never have discussed in their mother tongue. Ways of Doing is a rich source of stimulating and easy-to-use lesson ideas requiring minimal preparation. The activities, which are suitable for a range of levels and ages, deal with the following areas: - examining the patterns and processes in students' everyday life - exploring both the mother tongue and the foreign language - group dynamics - exploring and exploiting the course book - ways of learning - correction and feedback. There is also a special teacher development section.

A master of extreme situations, Charles Dickens populated his novels with unforgettable characters and elaborate settings. ""Critical Companion to Charles Dickens"" is an essential reference to everything one needs to know about Dickens and his work. This revised, reorganized, and fully updated revision of ""Charles Dickens A to Z"" contains extensive updates, including expanded commentary on the novels and on the major characters, as well as updates to reflect the latest in Dickens scholarship. This comprehensive, single-volume reference contains entries on this writer's works, including the characters in each work, crucial historical and thematic information, and critical discussion. It also includes entries on related people, places, themes, topics, and influences. Additional features include 50 illustrations, a chronology, a bibliography of primary and secondary sources, and much more. Coverage includes: a detailed discussion of Dickens' life; synopses and critical examinations of Dickens's published works, major and minor, with extensive analyses of his major novels, including ""David Copperfield"", ""Bleak House"", ""Oliver Twist"", ""A Christmas Carol"", and more; entries on the characters in his fiction, with major characters receiving extensive commentary; profiles of friends, family, and contemporaries, as well as the places important to Dickens' life and fiction; and discussions of themes and important, broader topics.

International Business Growth Strategies for Emerging Markets: Creating Sustainable Entrepreneurial Expansion is a comprehensive introductory guide to taking sustainable business into, and doing business within, the world’s fastest-growing economies. The authors, multi-cultural seasoned experts in accounting, finance, law, and strategy, stress the fundamental importance of sustainability. They underline the critical role of research and analysis before action. The potential positive impact of AI and digital transformation is a consistent theme. Drawing on their own experiences and a rich panoply of relevant literature, the authors highlight opportunities, risks, and proven techniques for market entry. Primarily written to inform undergraduate and postgraduate business students, the book also appeals to executives and managers tasked with crafting successful plans for businesses contemplating foundation or expansion in a world of unlimited potential.

International Business Growth Strategies for Emerging Markets: Creating Sustainable Entrepreneurial Expansion is a comprehensive introductory guide to taking sustainable business into, and doing business within, the world’s fastest-growing economies. The authors, multi-cultural seasoned experts in accounting, finance, law, and strategy, stress the fundamental importance of sustainability. They underline the critical role of research and analysis before action. The potential positive impact of AI and digital transformation is a consistent theme. Drawing on their own experiences and a rich panoply of relevant literature, the authors highlight opportunities, risks, and proven techniques for market entry. Primarily written to inform undergraduate and postgraduate business students, the book also appeals to executives and managers tasked with crafting successful plans for businesses contemplating foundation or expansion in a world of unlimited potential.

Addiction: Psychology and Treatment brings together leading psychologists to provide a comprehensive overview of the psychology of addictions and their treatment across specialities and types of services. Emphasises the use of several approaches including CBT, psychodynamic and systemic and family treatments, and consideration of the wider picture of addictionsAs well as the theories, gives a clear overview of the application of these modelsReflects the very latest developments in the role played by psychological perspectives and interventions in the recovery agenda for problem drug and alcohol users

This report is an output of the fourth research track (Track 4) of WERF’s strategic asset management research program ‘Asset Management Communication and Implementation’ (SAM1R06). Track 4 addressed ‘remaining asset life’, and had the overall objective of contributing to the development of techniques, tools and methods for estimating residual life of wastewater assets. Track 4 research was planned to be undertaken in a staged manner, so as to provide a stepwise development of concepts and protocols. To this end, the research team has produced a synthesis of knowledge in relation to “end of life” and “remaining asset life”, which is the subject of this report. Drawing on the literature and the knowledge-base of the research team and industry partners, information is presented on the range of factors that influence the life of the different asset classes involved in the provision of wastewater services. A taxonomy of asset life is also given, along with a critical review of the conceptual linkages between risk, asset management and remaining asset life. A review of techniques used to assess remaining asset life is also included, as well as a detailed ‘state of the art’ review of modeling tools and approaches.  One of the key questions to be addressed in this initial stage of the research was the state of knowledge with respect to the estimation and prediction of remaining asset life, and if there is the capacity to translate between condition and performance data (e.g. the presence of significant defects) and the residual life of an asset. In this regard, this report builds on previous work undertaken by the research team into protocols for condition and performance assessments, as detailed in WERF (2007).