Peter Coveney - Böcker

Mark Twain's witty, satirical tale of childhood rebellion against hypocritical adult authority, the Penguin Classics edition of The Adventures of Huckleberry Finn is edited with a critical introduction by Peter Coveney.Mark Twain's story of a boy's journey down the Mississippi on a raft conveyed the voice and experience of the American frontier as no other work had done before. When Huck escapes from his drunken, abusive 'Pap' and the 'sivilizing' Widow Douglas with runaway slave Jim, he embarks on a series of adventures that draw him to feuding families and the trickery of the unscrupulous 'Duke' and 'Dauphin'. Beneath the exploits, however, are more serious undercurrents - of slavery, adult control and, above all, of Huck's struggle between his instinctive goodness and the corrupt values of society which threaten his deep and enduring friendship with Jim.Based on the first edition of 1884, The Adventures of Huckleberry Finn includes a chronology and list of further reading by Richard Maxwell.Samuel Langhorne Clemens (1835-1910) trained as a steamboat pilot on the Mississippi river; 'Mark Twain', a phrase used on riverboats to indicate that the water is two fathoms deep, became the pseudonym by which he was best known. After the Civil War, Twain turned to journalism, publishing his first short story in 1865. Dubbed 'the father of American literature' by William Faulkner, Twain led a colourful life of travelling, bankruptcy and great literary success.If you enjoyed The Adventures of Huckleberry Finn, you may like Mark Twain's The Adventures of Tom Sawyer, also available in Penguin Classics.'All modern American literature comes from one book by Mark Twain called Huckleberry Finn ... There has been nothing as good since'Ernest Hemingway'Huckleberry Finn, like other great works of imagination, can give to every reader whatever he is capable of taking from it'T.S. Eliot

By the end of the twenty-first century, computer-based modelling and simulation will be integral to the way clinical decisions are taken. Drugs will be selected on the basis of an individual patient's "digital profile", while clinical treatments will be tailor-made for the individual in question. For this to come to pass, however, we must prepare for a future where we can simulate our own bodies with precision, drawing upon remarkable advances in information technology, computer, mathematical, physical and engineering science, data management, and high performance computing. Computational Biomedicine lays the foundations for a new approach to the subject - one that unifies the different strands of a broad-ranging subject, and demonstrates how computational biomedicine is a powerful tool with the potential to revolutionise our understanding of the human body, and the therapeutic strategies available to maintain and protect it.Written by a team of world-leading experts in the field, it explores the modelling of physiological systems at different scales - cells, tissues, organs - before considering the issues around biomedical computing, and data collection and analysis. It emphasises how a theoretical understanding of computational biomedicine translates into practice, with illustrative examples and case studies used throughout.Computational Biomedicine is the perfect introduction to the subject for anyone new to the field, from student to researcher. Online Resource CentreThe Online Resource Centre to accompany Computational Biomedicine features figures from the book in electronic format, for download by registered adopters.

The visionary science behind the digital human twins that will enhance our health and our futureVirtual You is a panoramic account of efforts by scientists around the world to build digital twins of human beings, from cells and tissues to organs and whole bodies. These virtual copies will usher in a new era of personalized medicine, one in which your digital twin can help predict your risk of disease, participate in virtual drug trials, shed light on the diet and lifestyle changes that are best for you, and help identify therapies to enhance your well-being and extend your lifespan—but thorny challenges remain.In this deeply illuminating book, Peter Coveney and Roger Highfield reveal what it will take to build a virtual, functional copy of a person in five steps. Along the way, they take you on a fantastic voyage through the complexity of the human body, describing the latest scientific and technological advances—from multiscale modeling to extraordinary new forms of computing—that will make “virtual you” a reality, while also considering the ethical questions inherent to realizing truly predictive medicine.With an incisive foreword by Nobel Prize–winning biologist Venki Ramakrishnan, Virtual You is science at its most astounding, showing how our virtual twins and even whole populations of virtual humans promise to transform our health and our lives in the coming decades.