Richard W. Compans – författare

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14 produkter

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14 produkter

Segmented Negative Strand Viruses
Arenaviruses, Bunyaviruses, and Orthomyxoviruses
AvRichard W. Compans
E-bok
Engelska, 2013
783 kr
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Segmented Negative Strand Viruses: Arenaviruses, Bunyaviruses, and Orthomyxoviruses is a collection of proceedings presented at the 5th International Symposium on Negative Strand Viruses, held at Hilton Head, South Carolina, on September 11-17, 1983. The papers focus on three virus families with segmented negative RNA genomes: arenaviruses, bunyaviruses, and orthomyxoviruses. Emphasis is placed on the viruses'' replication strategies, gene organization, and biochemical and biological properties. Comprised of 56 chapters, this volume begins with an introduction to the genome structure, transcription, and genetics of arenaviruses, bunyaviruses, and orthomyxoviruses. The next section is devoted to these viruses'' gene expression, protein synthesis, and protein modification. Eukaryotic expression of cloned complementary DNA coding for influenza is considered, along with the functional expression and mutational analysis of influenza virus surface glycoproteins. Subsequent chapters explore viral proteins via antigenic and functional analyses; the biology and immunochemistry of the African arenaviruses Lassa and Mopeia; and the use of avian-human reassortant influenza A viruses as live vaccine viruses in humans. This book will be of interest to investigators, microbiologists, and molecular and cell biologists in fields such as molecular biology, genetics, viral immunology, infectious diseases, and vaccine development.
Del 433 - Current Topics in Microbiology and Immunology
Nanoparticles for Rational Vaccine Design
AvHarvinder Singh Gill,Richard W. Compans
Inbunden, Engelska, 2021
1 116 kr
Skickas inom 10-15 vardagar
This book introduces nanoparticles as a powerful platform for vaccine design. Current challenges in vaccine development are discussed and the unique advantages nanoparticles provide in overcoming these challenges are explored. The authors offer fascinating insights into the immunological assets of using nanoparticles as delivery vehicles or adjuvants and present different materials that are being used in nanoparticle-based vaccine development, covering peptides, proteins, polymers, virus-like particles, and liposomes.Its contemporary research insights and practical examples for applications make this volume an inspiring read for researchers and clinicians in vaccinology and immunology. Chapter "Liposome Formulations as Adjuvants for Vaccines" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Nanoparticles for Rational Vaccine Design
AvRichard W. Compans,Harvinder Singh Gill
E-bok
Engelska, 2021
1 455 kr
Läs direkt efter köp
This book introduces nanoparticles as a powerful platform for vaccine design. Current challenges in vaccine development are discussed and the unique advantages nanoparticles provide in overcoming these challenges are explored. The authors offer fascinating insights into the immunological assets of using nanoparticles as delivery vehicles or adjuvants and present different materials that are being used in nanoparticle-based vaccine development, covering peptides, proteins, polymers, virus-like particles, and liposomes.
Its contemporary research insights and practical examples for applications make this volume an inspiring read for researchers and clinicians in vaccinology and immunology.

Chapter "Liposome Formulations as Adjuvants for Vaccines" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Del 433 - Current Topics in Microbiology and Immunology
Nanoparticles for Rational Vaccine Design
AvHarvinder Singh Gill,Richard W. Compans
Häftad, Engelska, 2022
1 116 kr
Skickas inom 10-15 vardagar
This book introduces nanoparticles as a powerful platform for vaccine design. Current challenges in vaccine development are discussed and the unique advantages nanoparticles provide in overcoming these challenges are explored. The authors offer fascinating insights into the immunological assets of using nanoparticles as delivery vehicles or adjuvants and present different materials that are being used in nanoparticle-based vaccine development, covering peptides, proteins, polymers, virus-like particles, and liposomes.Its contemporary research insights and practical examples for applications make this volume an inspiring read for researchers and clinicians in vaccinology and immunology. Chapter "Liposome Formulations as Adjuvants for Vaccines" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Del 385 - Current Topics in Microbiology and Immunology
Influenza Pathogenesis and Control - Volume I
AvRichard W. Compans,Michael B. A. Oldstone
Inbunden, Engelska, 2014
1 671 kr
Skickas inom 10-15 vardagar
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
Influenza Pathogenesis and Control - Volume I
AvMichael B. A. Oldstone,Richard W. Compans
E-bok
PDF, Engelska, 2014
2 110 kr
Läs direkt efter köp
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
Del 386 - Current Topics in Microbiology and Immunology
Influenza Pathogenesis and Control - Volume II
AvMichael B. A. Oldstone,Richard W. Compans
Inbunden, Engelska, 2014
1 671 kr
Skickas inom 10-15 vardagar
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
Influenza Pathogenesis and Control - Volume II
AvRichard W. Compans,Michael B. A. Oldstone
E-bok
PDF, Engelska, 2014
2 105 kr
Läs direkt efter köp
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
Del 386 - Current Topics in Microbiology and Immunology
Influenza Pathogenesis and Control - Volume II
AvMichael B. A. Oldstone,Richard W. Compans
Häftad, Engelska, 2016
1 671 kr
Skickas inom 10-15 vardagar
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
Del 385 - Current Topics in Microbiology and Immunology
Influenza Pathogenesis and Control - Volume I
AvRichard W. Compans,Michael B. A. Oldstone
Häftad, Engelska, 2016
1 671 kr
Skickas inom 10-15 vardagar
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
Del 333 - Current Topics in Microbiology and Immunology
Vaccines for Pandemic Influenza
AvRichard W Compans,Walter A. Orenstein
Inbunden, Engelska, 2009
3 335 kr
Skickas inom 10-15 vardagar
Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans, resulting in numerous fatalities. The rapid expansion in their geographic distribution and the possibility that these viruses could acquire the ability to spread from person to person raises the risk that such a virus could cause a global pandemic with high morbidity and mortality. An effective influenza vaccine represents the best approach to prevent and control such an emerging pandemic. However, current influenza vaccines are directed at existing seasonal influenza viruses, which have little or no antigenic relationship to the highly pathogenic H5N1 strains. Concerns about pandemic preparedness have greatly stimulated research activities to develop eff- tive vaccines for pandemic influenza viruses, and to overcome the limitations inh- ent in current approaches to vaccine production and distribution. These limitations include the use of embryonated chicken eggs as the substrate for vaccine prod- tion, which is time-consuming and could involve potential biohazards in growth of new virus strains. Other limitations include the requirement that the current inac- vated influenza vaccines be administered using needles and syringes, requiring trained personnel, which could be a bottleneck when attempting to vaccinate large populations in mass campaigns. In addition, the current inactivated vaccines that are delivered by injection elicit limited protective immunity in the upper respiratory tract where the infection process is initiated.
Vaccines for Pandemic Influenza
AvWalter A. Orenstein,Richard W Compans
E-bok
PDF, Engelska, 2009
4 054 kr
Läs direkt efter köp
Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans, resulting in numerous fatalities. The rapid expansion in their geographic distribution and the possibility that these viruses could acquire the ability to spread from person to person raises the risk that such a virus could cause a global pandemic with high morbidity and mortality. An effective influenza vaccine represents the best approach to prevent and control such an emerging pandemic. However, current influenza vaccines are directed at existing seasonal influenza viruses, which have little or no antigenic relationship to the highly pathogenic H5N1 strains. Concerns about pandemic preparedness have greatly stimulated research activities to develop eff- tive vaccines for pandemic influenza viruses, and to overcome the limitations inh- ent in current approaches to vaccine production and distribution. These limitations include the use of embryonated chicken eggs as the substrate for vaccine prod- tion, which is time-consuming and could involve potential biohazards in growth of new virus strains. Other limitations include the requirement that the current inac- vated influenza vaccines be administered using needles and syringes, requiring trained personnel, which could be a bottleneck when attempting to vaccinate large populations in mass campaigns. In addition, the current inactivated vaccines that are delivered by injection elicit limited protective immunity in the upper respiratory tract where the infection process is initiated.
Del 333 - Current Topics in Microbiology and Immunology
Vaccines for Pandemic Influenza
AvRichard W Compans,Walter A. Orenstein
Häftad, Engelska, 2011
3 335 kr
Skickas inom 10-15 vardagar
Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans, resulting in numerous fatalities. The rapid expansion in their geographic distribution and the possibility that these viruses could acquire the ability to spread from person to person raises the risk that such a virus could cause a global pandemic with high morbidity and mortality. An effective influenza vaccine represents the best approach to prevent and control such an emerging pandemic. However, current influenza vaccines are directed at existing seasonal influenza viruses, which have little or no antigenic relationship to the highly pathogenic H5N1 strains. Concerns about pandemic preparedness have greatly stimulated research activities to develop eff- tive vaccines for pandemic influenza viruses, and to overcome the limitations inh- ent in current approaches to vaccine production and distribution. These limitations include the use of embryonated chicken eggs as the substrate for vaccine prod- tion, which is time-consuming and could involve potential biohazards in growth of new virus strains. Other limitations include the requirement that the current inac- vated influenza vaccines be administered using needles and syringes, requiring trained personnel, which could be a bottleneck when attempting to vaccinate large populations in mass campaigns. In addition, the current inactivated vaccines that are delivered by injection elicit limited protective immunity in the upper respiratory tract where the infection process is initiated.
Del 170 - Current Topics in Microbiology and Immunology
Protein Traffic in Eukaryotic Cells
Selected Reviews
AvRichard W Compans
Häftad, Engelska, 2011
1 116 kr
Skickas inom 10-15 vardagar
Understanding the mechanisms involved in intracellular movement and localization of proteins is a central issue in cell biology. This volume is concerned with the events involved in the transport of membrane proteins, and the contents of vesicular compartments, to their ultimate destinations. In several chapters, particular attention is given to studies with viruses that are assembled by budding at specific membrane sites within the cell or at the cell surface; studies with such viral systems have provided significant insights into membrane biogenesis.

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Richard W. Compans – författare

Segmented Negative Strand Viruses

Nanoparticles for Rational Vaccine Design

Nanoparticles for Rational Vaccine Design

Nanoparticles for Rational Vaccine Design

Influenza Pathogenesis and Control - Volume I

Influenza Pathogenesis and Control - Volume I

Influenza Pathogenesis and Control - Volume II

Influenza Pathogenesis and Control - Volume II

Influenza Pathogenesis and Control - Volume II

Influenza Pathogenesis and Control - Volume I

Vaccines for Pandemic Influenza

Vaccines for Pandemic Influenza

Vaccines for Pandemic Influenza

Protein Traffic in Eukaryotic Cells

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