Sangram S. Sisodia – författare
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6 produkter
6 produkter
Inbunden, Engelska, 2006
1 668 kr
Skickas inom 10-15 vardagar
This book examines every major aspect of Alzheimer’s disease (AD). It provides exciting, comprehensive and up-to-date summaries of the most important recent advances in the genetic, molecular, biochemical, and cell biological studies of AD. There has been no scholarly research volume on AD published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins. Treatment of symptoms with therapeutic drugs is discussed, along with outcomes of and problems inherent in clinical trials for AD. The studies and advances described in this volume will help to accelerate the process of rational drug discovery and soon serve to extend and enhance the mental health and lifespan of our burgeoning elderly population.
E-bok
PDF, Engelska, 20072 110 kr
Läs direkt efter köp
This book examines every major aspect of Alzheimer's disease (AD). It provides exciting, comprehensive and up-to-date summaries of the most important recent advances in the genetic, molecular, biochemical, and cell biological studies of AD. There has been no scholarly research volume on AD published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins. Treatment of symptoms with therapeutic drugs is discussed, along with outcomes of and problems inherent in clinical trials for AD. The studies and advances described in this volume will help to accelerate the process of rational drug discovery and soon serve to extend and enhance the mental health and lifespan of our burgeoning elderly population.
E-bok
PDF, Engelska, 200310 997 kr
Läs direkt efter köp
Alzheimer''s Disease is an ever present problem affecting millions of people around the world and, as people''s average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume provides a unique source of reference to the important work being done in this field, it gives academics and clinicians an opportunity to learn about cutting edge developments and covers all aspects of Alzheimer''s Disease, including diagnosis, clinical course, epidemiological course and therapeutics and disease mechanisms. Alzheimer''s Disease: Advances in Etiology, Pathogenesis and Therapeutics will provide essential information for basic and clinical researchers in Alzheimer''s Disease and other dementias as well as for those who care for patients.
Inbunden, Engelska, 2001
9 344 kr
Skickas inom 11-20 vardagar
Alzheimer's Disease is an ever present problem affecting millions of people around the world and, as people's average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume provides a unique source of reference to the important work being done in this field, it gives academics and clinicians an opportunity to learn about cutting edge developments and covers all aspects of Alzheimer's Disease, including diagnosis, clinical course, epidemiological course and therapeutics and disease mechanisms. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics will provide essential information for basic and clinical researchers in Alzheimer's Disease and other dementias as well as for those who care for patients.
Häftad, Engelska, 2010
1 668 kr
Skickas inom 10-15 vardagar
This book examines every major aspect of Alzheimer’s disease (AD). It provides exciting, comprehensive and up-to-date summaries of the most important recent advances in the genetic, molecular, biochemical, and cell biological studies of AD. There has been no scholarly research volume on AD published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins. Treatment of symptoms with therapeutic drugs is discussed, along with outcomes of and problems inherent in clinical trials for AD. The studies and advances described in this volume will help to accelerate the process of rational drug discovery and soon serve to extend and enhance the mental health and lifespan of our burgeoning elderly population.
Inbunden, Engelska, 2026
2 736 kr
Kommande
This new edition provides comprehensive and authoritative coverage of the most important recent advances in the genetic, molecular, biochemical, and cell biological studies of Alzheimer's disease. The chapters explore the physiology of polypeptides involved in early-onset and late-onset gene variants, degradation and clearance, and the role of tau. An emerging and exciting theme in the field is the seeding and spreading of toxic, misfolded protein species in the CNS; selected chapters review the nature of these toxic species and the underlying molecular and cellular mechanisms that drive disease pathogenesis. Additional chapters examine the development of organoids to test mechanisms, role of BDNF and neurogenesis in Alzheimer’s models, roles of peripheral immune cells, and the microbiome on modulation of Alzheimer's-like pathologies and neuroinflammation. The book also covers what are perhaps the most compelling new findings over the past decade: the identification of genetic variants in genes involved in innate immunity that predispose individuals to late-onset Alzheimer’s disease. Also, the new edition covers the data from animal models and humans that have led to the emergence of key biomarkers and clinical trials for Alzheimer’s disease that have real promise for changing the course of disease.