Uma Rani Sinniah – författare

Bioactive compounds produced by natural sources, such as plants, microbes, endophytic fungi, etc., can potentially be applied in various fields, including agriculture, biotechnology and biomedicine. Several bioactive compounds have proved to be invaluable in mediating plant-microbe interactions, and promoting plant growth and development. Due to their numerous health-promoting properties, these compounds have been widely used as a source of medication since ancient times. However, there is an unprecedented need to meet the growing demand for natural bioactive compounds in the flavor and fragrance, food, and pharmaceutical industries. Moreover, discovering new lead molecules from natural sources is essential to overcoming the rising number of new diseases. In this regard, natural bioactive compounds hold tremendous potential for new drug discovery. Therefore, this field of research has become a vital area for researchers interested in understanding the chemistry,biosynthetic mechanisms, and pharmacological activities of these bioactive metabolites. This book describes the basics of bioactive plant compounds, their chemical properties, and their pharmacological biotechnological properties with regard to various human diseases and applications in the drug, cosmetics and herbal industries. It offers a valuable asset for all students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.

Bioactive compounds produced by natural sources, such as plants, microbes, endophytic fungi, etc., can potentially be applied in various fields, including agriculture, biotechnology and biomedicine. Several bioactive compounds have proved to be invaluable in mediating plant-microbe interactions, and promoting plant growth and development. Due to their numerous health-promoting properties, these compounds have been widely used as a source of medication since ancient times. However, there is an unprecedented need to meet the growing demand for natural bioactive compounds in the flavor and fragrance, food, and pharmaceutical industries. Moreover, discovering new lead molecules from natural sources is essential to overcoming the rising number of new diseases. In this regard, natural bioactive compounds hold tremendous potential for new drug discovery. Therefore, this field of research has become a vital area for researchers interested in understanding the chemistry,biosynthetic mechanisms, and pharmacological activities of these bioactive metabolites. This book describes the basics of bioactive plant compounds, their chemical properties, and their pharmacological biotechnological properties with regard to various human diseases and applications in the drug, cosmetics and herbal industries. It offers a valuable asset for all students, educators, researchers, and healthcare experts involved in agronomy, ecology, crop science, molecular biology, stress physiology, and natural products.

To ensure sustainable production of pharmaceutically significant active metabolites (from natural sources) with anti-aging properties, biotechnological interventions become the need of the hour when global warming and environmental pollution result in increasing UV radiation and, consequently, sunburn and aging of the tissue. In that context, the introductory chapter of this book outlines the concept and importance of medicinal plants available in local, national, and global regions that are rich in bioactive compounds responsible for anti-aging effects, along with their distribution, status, and limitations of conventional propagation and their biotechnological enhancement. The subsequent chapter provides insights into how environmental changes affect the anti-aging properties of metabolites in medicinal plants. There are dedicated chapters that provide insights on the genetic basis of anti-aging activity, the chemistry and physiology of modes of action, as well as the cellular mechanisms of secondary metabolites, along with the role of phytohormones for in vitro mass propagation, somatic embryos, their maturation, and the regeneration of anti-aging medicinal plants. Enhancement of anti-aging properties and the production of secondary metabolites with the interventions of LEDs, cell suspension, elicitation, bioreactor, auto-polyploidization, induced mutagenesis, and nanotechnology, as well as CRISPR/Cas9-mediated genome editing. Apart from genetic improvements, focus is given on conservation and exchange of anti-aging medicinal plants via cryopreservation and synthetic seed technologies. In conclusion, the study comprehensively covers secondary metabolite extraction techniques and the clinical evidence and significance of these metabolites. Expert scientists from 15 different countries, such as Argentina, Belgium, Botswana, Cameroon, China, Cuba, Czech Republic, Egypt, France, India, Japan, Mexico, South Africa, Türkiye, and Vietnam, have contributed 14 insightful chapters to this book. It is noteworthy to mention that there is a sustainable hunt for possible novel anti-aging compounds from natural resources, especially plants and herbs, and this book will be a potential guideline to facilitate that endeavor.