Vipin Chandra Kalia – författare

This book set provides an overview of the methodologies of bio-processing, sustainable production of agri-food waste, the assessment and management of bioactive molecule production from microbial-valorization of agri-food waste, and their industrial applications. This set also provides an overview of the tools and processes that make or modify products and improve plants for specific uses, and discusses the utilization of livestock in agricultural systems by the use of microbial approach. The authors examine technical concepts and processes for the enhanced bioproduction of various bio-products for commercial interest. They also discuss the main process conditions needed to overcome the difficulties of using waste as alternative raw materials and cover the main processes for obtaining the relevant enzymes for commercial purpose. They then review the technical-economic details on the advantages and disadvantages of exploring the waste recovery chain. Fianlly, they explore the main technological advances in the recovery of residues in functional products and encompass solid research to explore the broad potential of future microbial applications. This book is intended for biotechnologists, biologists, bioengineers, biochemists, microbiologists, food technologists, enzymologists, and related researchers.

This book set provides an overview of the methodologies of bio-processing, sustainable production of agri-food waste, the assessment and management of bioactive molecule production from microbial-valorization of agri-food waste, and their industrial applications. This set also provides an overview of the tools and processes that make or modify products and improve plants for specific uses, and discusses the utilization of livestock in agricultural systems by the use of microbial approach. The authors examine technical concepts and processes for the enhanced bioproduction of various bio-products for commercial interest. They also discuss the main process conditions needed to overcome the difficulties of using waste as alternative raw materials and cover the main processes for obtaining the relevant enzymes for commercial purpose. They then review the technical-economic details on the advantages and disadvantages of exploring the waste recovery chain. Fianlly, they explore the main technological advances in the recovery of residues in functional products and encompass solid research to explore the broad potential of future microbial applications. This book is intended for biotechnologists, biologists, bioengineers, biochemists, microbiologists, food technologists, enzymologists, and related researchers.

Enzymes are biological molecules of great relevance. In addition to the fundamental role in metabolic reactions, they have diverse applications in industrial processes in generating products of great commercial utility for the most diverse areas. Thus, industries seek to expand research to select microorganisms capable of producing enzymes according to their commercial objectives. Considering the diversity of the microbiota kingdom, as well as the diversity of mode of action of different classes of enzymes, this is an area that deserves constant investments to elucidate new applications, considering that these biological catalysts have great selectivity and a diversity of mode of action, reusable, and operate under mild process conditions, becoming the bridge for the development of sustainable processes and for adding value to commercial products. This book is intended for bioengineers, biologists, biochemists, biotechnologists, microbiologists, food technologists, enzymologists, and related professionals/ researchers.• Explores recent advances in the valorization of agri-food waste into enzymes • Explores the main technological advances in the recovery of residues and their use for the production of enzymes• Provides technical concepts on the production of various enzymes of commercial interest • Presents the main classes of enzymes obtained from alternative raw materials.

Food ingredients are important molecules of the most diverse chemical classes responsible for conferring nutrition, stability, color, flavor, rheological and sensorial characteristics, in addition to several other important uses in the food industry. In this way, the production routes of these ingredients have gained more and more attention from consumers and producing industries, who expect that, in addition to their technological properties, these ingredients are still obtained without synthetic means, with savings of natural resources and mainly with less environmental impact. This book is intended for bioengineers, biologists, biochemists, biotechnologists, microbiologists, food technologists, enzymologists, and related professionals/ researchers. • Explores recent advances in the valorization of agri-food waste into food ingredients • Provides technical concepts on the production of various food ingredients of commercial interest• Explores novel technologically advanced strategies for the extraction of bioactive compounds from food wastes• Presents important classes of food ingredients obtained from alternative raw materials• Presents sustainable food waste resources and management strategies• Presents different pretreatment technologies and green extraction methodologies to support a green environment in the circular economy concept.• Challenges in applications of re-derived bioactive compounds from food wastes in food formulations

Enzymes are biological molecules of great relevance. In addition to the fundamental role in metabolic reactions, they have diverse applications in industrial processes in generating products of great commercial utility for the most diverse areas. Thus, industries seek to expand research to select microorganisms capable of producing enzymes according to their commercial objectives. Considering the diversity of the microbiota kingdom, as well as the diversity of mode of action of different classes of enzymes, this is an area that deserves constant investments to elucidate new applications, considering that these biological catalysts have great selectivity and a diversity of mode of action, reusable, and operate under mild process conditions, becoming the bridge for the development of sustainable processes and for adding value to commercial products. This book is intended for bioengineers, biologists, biochemists, biotechnologists, microbiologists, food technologists, enzymologists, and related professionals/ researchers.• Explores recent advances in the valorization of agri-food waste into enzymes • Explores the main technological advances in the recovery of residues and their use for the production of enzymes• Provides technical concepts on the production of various enzymes of commercial interest • Presents the main classes of enzymes obtained from alternative raw materials.

Food ingredients are important molecules of the most diverse chemical classes responsible for conferring nutrition, stability, color, flavor, rheological and sensorial characteristics, in addition to several other important uses in the food industry. In this way, the production routes of these ingredients have gained more and more attention from consumers and producing industries, who expect that, in addition to their technological properties, these ingredients are still obtained without synthetic means, with savings of natural resources and mainly with less environmental impact. This book is intended for bioengineers, biologists, biochemists, biotechnologists, microbiologists, food technologists, enzymologists, and related professionals/ researchers. • Explores recent advances in the valorization of agri-food waste into food ingredients • Provides technical concepts on the production of various food ingredients of commercial interest• Explores novel technologically advanced strategies for the extraction of bioactive compounds from food wastes• Presents important classes of food ingredients obtained from alternative raw materials• Presents sustainable food waste resources and management strategies• Presents different pretreatment technologies and green extraction methodologies to support a green environment in the circular economy concept.• Challenges in applications of re-derived bioactive compounds from food wastes in food formulations

This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way.

This book gives an overview on techniques and future perspectives of various aspects of waste biomass management. It also presents the economic and environmental evaluation, and also the monetary value-benefits and sustainability of the different processes. Recycling processes of lignocellulosic biomass from palm oil mill waste are covered, as well as from sugar industry waste and agriculture waste. It also includes thermal and non-thermal technologies for resource recovery from waste biomass. Challenges in the reuse and recycling of waste biomass are discussed, i.e., the hygienic safety in biomass management and bioremediation technologies for conversion into valuable products. The book is aiming at scientists, researchers and students alike, who are working in the research areas pertaining to waste management

This contributed volume sheds new light on waste management and the production of biofuels. The authors share insights into microbial applications to meet the challenges of environmental pollution and the ever- growing need for renewable energy. They also explain how healthy and balanced ecosystems can be created and maintained using strategies ranging from oil biodegration and detoxification of azo dyes to biofouling. In addition, the book illustrates how the metabolic abilities of microorganisms can be used in microbial fuel-cell technologies or for the production of biohydrogen. It inspires young researchers and experienced scientists in the field of microbiology to explore the application of green biotechnology for bioremediation and the production of energy, which will be one of the central topics for future generations.

This contributed volume provides insights into multiple applications using microbes to promote productivity in agriculture, to produce biochemicals or to respond to challenges in biomedicine. It highlights the microbial production of nanocompounds with medical functionality alongside new anti-mycobacterial strategies, and introduces plant-growth-promoting Rhizobacteria as well as the correlation between biofilm formation and crop productivity. Further, the authors illustrate the green synthesis of biochemical compounds, such as hydroxamid acid or biosurfactants, using microbial and fungal enzymes. It inspires young researchers and experienced scientists in the field of microbiology to explore the combined use of green, white and red biotechnology for industrial purposes, which will be one of the central topics for future generations.

This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome.

This book gives an overview on techniques and future perspectives of various aspects of waste biomass management. Recycling processes of lignocellulosic biomass from palm oil mill waste are covered, as well as from sugar industry waste and agriculture waste.

This contributed volume sheds new light on waste management and the production of biofuels. The authors share insights into microbial applications to meet the challenges of environmental pollution and the ever- growing need for renewable energy. They also explain how healthy and balanced ecosystems can be created and maintained using strategies ranging from oil biodegration and detoxification of azo dyes to biofouling. In addition, the book illustrates how the metabolic abilities of microorganisms can be used in microbial fuel-cell technologies or for the production of biohydrogen. It inspires young researchers and experienced scientists in the field of microbiology to explore the application of green biotechnology for bioremediation and the production of energy, which will be one of the central topics for future generations.

This contributed volume provides insights into multiple applications using microbes to promote productivity in agriculture, to produce biochemicals or to respond to challenges in biomedicine.

Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs.

This book highlights the efforts made by distinguished scientific researchers world-wide to meet two key challenges: i) the limited reserves of polluting fossil fuels, and ii) the ever-increasing amounts of waste being generated. These case studies have brought to the foreground certain innovative biological solutions to real-life problems we now face on a global scale: environmental pollution and its role in deteriorating human health. The book also highlights major advances in microbial metabolisms, which can be used to produce bioenergy, biopolymers, bioactive molecules, enzymes, etc. Around the world, countries like China, Germany, France, Sweden and the US are now implementing major national programs for the production of biofuels. The book provides information on how to meet the chief technical challenges – identifying an industrially robust microbe and cheap raw material as feed. Of the various possibilities for generating bioenergy, the most attractive is the microbial production of biohydrogen, which has recently gained significant recognition worldwide, due to its high efficiency and eco-friendly nature. Further, the book highlights factors that can make these bioprocesses more economical, especially the cost of the feed. The anaerobic digestion (AD) process is more advantageous in comparison to aerobic processes for stabilizing biowastes and producing biofuels (hydrogen, biodiesel, 1,3-propanediol, methane, electricity), biopolymers (polyhydroxyalkanoates, cellulose, exopolysaccharides) and bioactive molecules (such as enzymes, volatile fatty acids, sugars, toxins, etc.) for biotechnological and medical applications. Information is provided on how the advent of molecular biological techniques can provide greater insights into novel microbial lineages. Bioinformatic tools and metagenomic techniques have extended the limits to which these biological processes can be exploited to improvehuman welfare. A new dimension to these scientific works has been added by the emergence of synthetic biology. The Big Question is: How can these Microbial Factories be improved through metabolic engineering and what cost targets need to be met?

This book highlights the efforts made by distinguished scientific researchers world-wide to meet two key challenges: i) the limited reserves of polluting fossil fuels, and ii) the ever-increasing amounts of waste being generated. These case studies have brought to the foreground certain innovative biological solutions to real-life problems we now face on a global scale: environmental pollution and its role in deteriorating human health. The book also highlights major advances in microbial metabolisms, which can be used to produce bioenergy, biopolymers, bioactive molecules, enzymes, etc. Around the world, countries like China, Germany, France, Sweden and the US are now implementing major national programs for the production of biofuels. The book provides information on how to meet the chief technical challenges – identifying an industrially robust microbe and cheap raw material as feed. Of the various possibilities for generating bioenergy, the most attractive is the microbial production of biohydrogen, which has recently gained significant recognition worldwide, due to its high efficiency and eco-friendly nature. Further, the book highlights factors that can make these bioprocesses more economical, especially the cost of the feed. The anaerobic digestion (AD) process is more advantageous in comparison to aerobic processes for stabilizing biowastes and producing biofuels (hydrogen, biodiesel, 1,3-propanediol, methane, electricity), biopolymers (polyhydroxyalkanoates, cellulose, exopolysaccharides) and bioactive molecules (such as enzymes, volatile fatty acids, sugars, toxins, etc.) for biotechnological and medical applications. Information is provided on how the advent of molecular biological techniques can provide greater insights into novel microbial lineages. Bioinformatic tools and metagenomic techniques have extended the limits to which these biological processes can be exploited to improve human welfare. A new dimension to these scientific works has been added by the emergence of synthetic biology. The Big Question is: How can these Microbial Factories be improved through metabolic engineering and what cost targets need to be met?

Microbial relationships with all life forms can be as free living, symbiotic or pathogenic. Human beings harbor 10 times more microbial cells than their own. Bacteria are found on the skin surface, in the gut and other body parts. Bacteria causing diseases are the most worrisome. Most of the infectious diseases are caused by bacterial pathogens with an ability to form biofilm. Bacteria within the biofilm are up to 1000 times more resistant to antibiotics. This has taken a more serious turn with the evolution of multiple drug resistant bacteria. Health Departments are making efforts to reduce high mortality and morbidity in man caused by them. Bacterial Quorum sensing (QS), a cell density dependent phenomenon is responsible for a wide range of expressions such as pathogenesis, biofilm formation, competence, sporulation, nitrogen fixation, etc. Majority of these organisms that are important for medical, agriculture, aquaculture, water treatment and remediation, archaeological departments are: Aeromonas, Acinetobacter, Bacillus, Clostridia, Enterococcus, Pseudomonas, Vibrio and Yersinia spp. Biosensors and models have been developed to detect QS systems. Strategies for inhibiting QS system through natural and synthetic compounds have been presented here. The biotechnological applications of QS inhibitors (QSIs) in diverse areas have also been dealt with. Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs. This book addresses a few questions. Will bacteria develop mechanisms to evade QSIs? Are we watching yet another defeat at the hands of bacteria? Or will we be acting intelligently and survive the onslaughts of this Never Ending battle?

This book comprehensively discusses the latest research in the area of metabolic engineering. Metabolic engineering solutions for bioactive compounds are now being derived by means of heterologous gene expression, in a wide range of organisms. The book provides an overview of the model systems being employed for metabolic manipulation to yield bioactive molecules, such as single-cell proteins, antibody generation, metabolites, proteases, chaperones, therapeutic proteins, nanomaterials, polymeric conjugates, dendrimers and nanoassemblies, Escherichia coli, Agrobacterium, Saccharomyces cerevisiae and cell lines, etc. In addition, it shares insights into the scope of these methods in the areas of prevention, diagnosis and treatment of diseases, e.g. immunotherapy for curing various diseases like cancer, allergies, autoimmune diseases, etc.

The existence of living organisms in diverse ecosystems has been the focus of interest to human beings, primarily to obtain insights into the diversity and dynamics of the communities. This book discusses how the advent of novel molecular biology techniques, the latest being the next-generation sequencing technologies, helps to elucidate the identity of novel organisms, including those that are rare.The book highlights the fact that oceans, marine environments, rivers, mountains and the gut are ecosystems with great potential for obtaining bioactive molecules, which can be used in areas such as agriculture, food, medicine, water supplies and bioremediation. It then describes the latest research in metagenomics, a field that allows elucidation of the maximum biodiversity within an ecosystem, without the need to actually grow and culture the organisms. Further, it describes how human-associated microbes are directly responsible for our health and overall wellbeing.<

This book argues that the sustainable management of resources requires a systematic approach that primarily involves the integration of green innovative biotechnological strategies and eco-engineering. It discusses how microbial community intelligence can be used for waste management and bio-remediation and explains how biological processes can be optimized by integrating genomics tools to provide perspectives on sustainable development.    The book describes the application of modern molecular techniques such as fluorescence in situ hybridization (FISH), highly sensitive catalyzed reporter deposition (CARD)-FISH, in situ DNA-hybridization chain reaction (HCR) and methods for detecting mRNA and/or functional genes to optimize bioprocessess. These techniques, supplemented with metagenomic analysis, reveal that a large proportion of micro-organisms still remain to be identified and also that they play a vital role in establishing bioprocesses.

This book explains how the biological systems and their functions are driven by genetic information stored in the DNA, and their expression driven by different factors. The soft computing approach recognizes the different patterns in DNA sequence and try to assign the biological relevance with available information.The book also focuses on using the soft-computing approach to predict protein-protein interactions, gene expression and networks. The insights from these studies can be used in metagenomic data analysis and predicting artificial neural networks.

This book discusses the practical applications of quorum sensing inhibitors for both human and plant health. Quorum sensing inhibitors that disrupt microbial biofilms can be employed to treat bacterial infections. The book describes the various bioactive molecules that can serve as quorum sensing inhibitors to combat deadly bacterial infections, in addition to several synthetic quorum sensing inhibitors.Quorum sensing is the mechanism through which bacteria develop antibiotic resistance. Intended to provide a clearer understanding of the practical applications of quorum sensing inhibitors, the book details how the problem of antibiotic resistance can be countered through the intelligent application of quorum sensing inhibitors.

This book delves into the biotechnological applications of Quorum sensing (QS)- a peculiar gene-regulatory process of some microorganisms. Quorum Sensing allows a large bacterial population to work together in a coordinated manner to carry out metabolic activities, which individual bacterium cannot. The different chapters describe how, associating bioremediation process with energy generation is an economical proposal, for reducing pollution and managing biowastes. The book discusses how QS can be exploited for biotechnological applications in generating bioproducts, bioenergy, bioremediation, biosensors, health and agricultural activities. It further highlights how QS is becoming an integral part of synthetic biology for genetic circuits for producing: (i) novel products, (ii) biosensors, (iii) bioactive molecules, etc. The book is divided into different sections for a clear understanding of the applicability of QS in, the Environment, Energy,Agriculture and Health sectors.

This book presents the latest research on the uses of polyhydroxyalkanoates (PHA), introducing readers to these natural, biodegradable polyesters produced by microorganisms, their functions and applications. The individual chapters discuss the various potentials of these bioplastics, which offer an attractive alternative to non-biodegradable plastics. The book also describes the diverse medical and biomedical applications of PHAs, including their use as drug carriers, memory enhancers, and biocontrol agents, and examines their role in creating a more sustainable economy – which is the need of the hour.

The soft computing approach recognizes the different patterns in DNA sequence and try to assign the biological relevance with available information.The book also focuses on using the soft-computing approach to predict protein-protein interactions, gene expression and networks.

The book describes the various bioactive molecules that can serve as quorum sensing inhibitors to combat deadly bacterial infections, in addition to several synthetic quorum sensing inhibitors.Quorum sensing is the mechanism through which bacteria develop antibiotic resistance.

This book delves into the biotechnological applications of Quorum sensing (QS)- a peculiar gene-regulatory process of some microorganisms. The book discusses how QS can be exploited for biotechnological applications in generating bioproducts, bioenergy, bioremediation, biosensors, health and agricultural activities.

This book argues that the sustainable management of resources requires a systematic approach that primarily involves the integration of green innovative biotechnological strategies and eco-engineering.