Yves Queneau - Böcker

With the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in the field. As the synthesis of novel carbohydrates and carbohydrate mimetics continues to be a major challenge for organic chemists, not least because of the increasingly interdisciplinary nature of carbohydrate science, Carbohydrate Chemistry Volume 41 will prove invaluable. Covering both chemical and biological science, this series collates modern carbohydrate research from theory to application and will be of great benefit to any researcher who wishes to learn about the latest developments in the carbohydrate field.

With the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field. This invaluable volume contains analysed, evaluated and distilled information on the latest in carbohydrate research. The discovery and synthesis of novel carbohydrates and mimetics with diverse applications continues to be a major challenge for carbohydrate chemists. The understanding of the structure and function of carbohydrates and glycoconjugates remains vital in medicine and molecular biology.This volume collates modern carbohydrate research from theory to application and demonstrates the importance of carbohydrates in new lead generation. It is of benefit to any researcher who wishes to learn about the latest developments in the carbohydrate field.

Demonstrating the interdisciplinary nature of modern glycosciences, this volume covers research in the fields of polysaccharides and small carbohydrates from the synthetic and structural viewpoints, with applications ranging from biology to the bioeconomy. Key aspects of the synthesis and properties of imino disaccharides and regioselective glycosylation reactions are reviewed, glycosyltransferase inhibitors are shown to be potential future therapeutic agents, protein-carbohydrate interactions in plant cell-wall biodegradation are targeted by the use of glycan microarrays, biological properties of polysaccharidic microbial surface antigens are discussed with respect to their intimate structure, and contributions on carbohydrate-based hydrogelators, green/blue sugar-based surfactants and carbohydrate-based green solvents illustrate the modern design of tomorrow's chemicals. With the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field and this book remains a valuable addition to any researcher's library.

The understanding of the structure and function of carbohydrates and glycoconjugates remains vital in many fields, notably in medicine and molecular biology. This new volume of Carbohydrate Chemistry contains critical reviews covering the latest findings in both chemical and biological sciences, and demonstrates the interdisciplinary nature of modern carbohydrate research. This book addresses diverse applications that continue to be major challenges for carbohydrate chemists. The oxidative deamination reactions and synthesis of N-acetylneuraminic acid derivatives, ketoheptoses, lipid A and analogs, the fascinating world of complex glycans in the interplay with Siglecs, carbohydrates and regenerative medicine, chemistry for the stereocontrol of glycosylation, and the impact of gold chemistry in carbohydrate research are some of the topics presented in this volume 44, which will certainly benefit any researcher who wishes to learn about the latest developments in the carbohydrate field.

The understanding of the structure, recognition, and function of carbohydrates and glycoconjugates remains crucial in diverse areas at the interface of biology, chemistry and biotechnology and is driving innovation in biomedical and material sciences. This new volume contains original work and critical reviews covering the current state-of-the-art and scientific advances in carbohydrate research and demonstrates cross-disciplinary areas within the field of glycosciences. Most of the chapters are contributions from speakers of the 14th International Meeting of the Portuguese Carbohydrate Group – GLUPOR 14, held in Caparica, Lisbon in January 2023. GLUPOR international meetings have a long history, with the first taking place in Lisbon in 1995 organized by Professor Amélia Pilar Rauter and resulting from the foundation of the Portuguese Carbohydrate Group of the Portuguese Chemical Society. Following the first meeting, GLUPOR has been held every two years providing a unique opportunity to strengthen collaborations and opening new directives for the carbohydrate community. The topics in Volume 46 cover current methods for stereoselective synthesis of carbohydrates, technologies for increasing the efficiency of glycosylation reactions, value-added carbohydrate-based materials towards more sustainable approaches, molecular recognition and structural-based approaches and bioinformatics to understand microbe–host interactions and to develop new applications in biotechnology and tools in the glycosciences. This set of reports will certainly benefit any researcher who wishes to learn about the latest developments in the carbohydrate field from basic to applied research.

The understanding of the structure, recognition, and function of carbohydrates and glycoconjugates remains crucial in diverse areas at the interface of biology, chemistry and biotechnology and is driving innovation in biomedical and material sciences. This new volume contains critical reviews covering the current state-of-the-art and scientific advances in carbohydrate research and demonstrates cross-disciplinary areas within the field of glycosciences. Amongst the topics covered in Volume 47 are reviews focusing on the role of glycans in mechanisms of disease, highlighting the perspectives and challenges in diagnosis and their therapeutic potential as immune-checkpoints in cancer, inflammation and autoimmunity, and also evidencing a role in the pathogenesis of neurodegenerative diseases, such as Parkinson’s disease. This volume also covers current knowledge on glycan biosynthesis at the molecular level to understand and exploit structural features in different biological settings: tumour-associated O-glycans in cancer, mycobacterial polysaccharides in infection and peptidoglycan in biofilm formation. Sustainable synthesis from biomass-derived carbohydrates is also reviewed in Volume 47, from a perspective of renewable resources, highlighting selected examples of the most relevant value-added compounds. Finally, the volume also gathers reviews on technology-driven research highlighting emergent chemical and glycoengineering approaches for accessing the cancer glycoproteome and lectin-based tools for targeting disease biomarkers.

In many fields, most notably medicine and molecular biology, the understanding of the structure and function of carbohydrates and glycoconjugates remains vital. This new volume contains critical reviews covering the latest findings in both chemical and biological sciences, and demonstrates the interdisciplinary nature of modern carbohydrate research. This book addresses diverse applications that continue to be major challenges for carbohydrate chemists. The book starts with a review of Gérard Descotes contribution to the field as a pioneer of French modern carbohydrate chemistry. Green nanocatalytic oxidation of free sugars, photosensitive glycomacrocycles, the application of disaccharides in supramolecular chemistry, recent advances in the radiation chemistry of polysaccharides, and the cell wall pectic rhamnogalacturonan II, an enigma in plant glycobiology are just some of the diverse topics presented in Volume 45. This set of reports will certainly benefit any researcher who wishes to learn about the latest developments in the carbohydrate field.

Volume 40 of Carbohydrate Chemistry: Chemical and Biological Approaches demonstrates the importance of the glycosciences for innovation and societal progress. Carbohydrates are molecules with essential roles in biology and also serve as renewable resources for the generation of new chemicals and materials. Honouring Professor André Lubineau’s memory, this volume resembles a special collection of contributions in the fields of green and low-carbon chemistry, innovative synthetic methodology and design of carbohydrate architectures for medicinal and biological chemistry.Green methodology is illustrated by accounts on the industrial development of water-promoted reactions (C-glycosylation, cycloadditions) and the design of green processes and synthons towards sugar-based surfactants and materials. The especially challenging transformations at the anomeric center are presented in several contributions on glycosylation methodologies using iron or gold catalysis, electrochemical or enzymatic (thio)glycosylation, exo-glycal chemistry and bioengineering of carbohydrate synthases. Then, synthesis and structure of multivalent and supramolecular oligosaccharide architectures are discussed and related to their physical properties and application potential, e.g. for deepening our understanding of biological processes, such as enzymatic pathways or bacterial adhesion, and design of antibacterial, antifungal and innovative anticancer vaccines or drugs.

Sucrose: A Prospering and Sustainable Organic Raw Material,By S. Peters, T. Rose, and M. Moser; Sucrose-Utilizing Transglucosidases for Biocatalysis, By I. André, G. Potocki-Véronèse, S. Morel, P. Monsan, and M. Remaud-Siméon; Difructose Dianhydrides DFAs) and DFA-Enriched Products as Functional Foods, By C. Ortiz Mellet and J. M. García Fernández; Development of Agriculture Left-Overs: Fine Organic Chemicals from Wheat Hemicellulose-Derived Pentoses, By F. Martel, B. Estrine, R. Plantier-Royon, N. Hoffmann, and C. Portella; Cellulose and Derivatives from Wood and Fibers as Renewable Sources of Raw-Materials, By J.A. Figueiredo, M.I. Ismael, C.M.S. Anjo, and A.P. Duarte; Olive Pomace, a Source for Valuable Arabinan-Rich Pectic Polysaccharides,By M. A. Coimbra, S. M. Cardoso, and J. A. Lopes-da-Silva; Oligomannuronates from Seaweeds as Renewable Sources for the Development of Green Surfactants,By T. Benvegnu and J.-F. Sassi; From Natural Polysaccharides to Materials for Catalysis, Adsorption, and Remediation, By F. Quignard, F. Di Renzo, and E. Guibal

Knoevenagel Reaction of Unprotected Sugars, By M.-C. Scherrmann ;Carbohydrate-Based Lactones: Synthesis and Applications, By N. M. Xavier, A. P. Rauter, and Y. Queneau; Heterogeneously-Catalyzed Conversion of Carbohydrates, By K. De Oliveira Vigier and F. Jérôme; Palladium-Catalyzed Telomerization of Butadiene with Polyols: From Mono to Polysaccharides, By S. Bouquillon, J. Muzart, C. Pinel, and F. Rataboul; Monosaccharides, By J.A. Galbis and M.G. García-Martín; Natural Sources, By L. Weignerová and V. Křen; Synthesis and Applications of Ionic Liquids Derived from Natural Sugars;By C. Chiappe, A. Marra, and A. Mele

Sucrose: A Prospering and Sustainable Organic Raw Material,By S. Peters, T. Rose, and M. Moser; Sucrose-Utilizing Transglucosidases for Biocatalysis, By I. André, G. Potocki-Véronèse, S. Morel, P. Monsan, and M. Remaud-Siméon; Difructose Dianhydrides DFAs) and DFA-Enriched Products as Functional Foods, By C. Ortiz Mellet and J. M. García Fernández; Development of Agriculture Left-Overs: Fine Organic Chemicals from Wheat Hemicellulose-Derived Pentoses, By F. Martel, B. Estrine, R. Plantier-Royon, N. Hoffmann, and C. Portella; Cellulose and Derivatives from Wood and Fibers as Renewable Sources of Raw-Materials, By J.A. Figueiredo, M.I. Ismael, C.M.S. Anjo, and A.P. Duarte; Olive Pomace, a Source for Valuable Arabinan-Rich Pectic Polysaccharides,By M. A. Coimbra, S. M. Cardoso, and J. A. Lopes-da-Silva; Oligomannuronates from Seaweeds as Renewable Sources for the Development of Green Surfactants,By T. Benvegnu and J.-F. Sassi; From Natural Polysaccharides to Materials for Catalysis, Adsorption, and Remediation, By F. Quignard, F. Di Renzo, and E. Guibal