RSC Biomolecular Sciences – serie
Visar alla böcker i serien RSC Biomolecular Sciences. Handla med fri frakt och snabb leverans.
28 produkter
Therapeutic Oligonucleotides
Av Jens Kurreck
Inbunden, 2008
2752 kr
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This book provides a comprehensive overview of the development of therapeutic oligonucleotides for therapeutic applications, touching on a number of additional oligonucleotides including a number of small interfering RNAs currently in various phases of clinical development. Written by leading …
Quantum Tunnelling in Enzyme-Catalysed Reactions
Av Rudolf Allemann, Nigel S Scrutton
Inbunden, 2009
2673 kr
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In recent years, there has been an explosion in knowledge and research associated with the field of enzyme catalysis and H-tunneling. Rich in its breath and depth, this introduction to modern theories and methods of study is suitable for experienced researchers and those new to the subject. Edited …
RNA Polymerases as Molecular Motors
Inbunden, 2009
2726 kr
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The cell can be viewed as a 'collection of protein machines' and understanding these molecular machines requires sophisticated cooperation between cell biologists, geneticists, enzymologists, crystallographers, chemists and physicists. To observe these machines in action, researchers have developed …
Oxidative Folding of Peptides and Proteins
Av Luis Moroder, Johannes Buchner
Inbunden, 2008
2586 kr
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The formation of disulfide bonds is probably the most influential modification of peptides and proteins. An elaborate set of cellular machinery exists to catalyze and guide this process. In recent years, significant developments have been made in both our understanding of the in vivo situation and …
Structural Virology
Av Mavis Agbandje-McKenna, Robert McKenna
Inbunden, 2010
2526 kr
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Over the last ten years, much effort has been devoted to improving the biophysical techniques used in the study of viruses. This has resulted in the visualization of these large macromolecular assemblages at atomic level, thus providing the platform for functional interpretation and therapeutic …
Molecular Simulations and Biomembranes
From Biophysics to Function
Av Mark S P Sansom, Philip C Biggin
Inbunden, 2010
2453 kr
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The need for information in the understanding of membrane systems has been caused by three things - an increase in computer power; methodological developments and the recent expansion in the number of researchers working on it worldwide. However, there has been no up-to-date book that covers the …
Natural Product Chemistry for Drug Discovery
Av Antony D Buss, Mark S Butler
Inbunden, 2009
2615 kr
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Natural Product Chemistry for Drug Discovery provides a comprehensive summary of where natural product chemistry is today in drug discovery. The book covers emerging technologies and case studies and is a source of up-to-date information on the topical subject of natural products. Natural products …
Ribozymes and RNA Catalysis
Av David M J Lilley, Fritz Eckstein
Inbunden, 2007
2039 kr
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The discovery that RNA could act as a macromolecular catalyst in the cell, signified a paradigm shift in molecular biology. Ribozymes and RNA Catalysis takes the reader through the origins of catalysis in RNA and necessarily includes significant discussion of structure and folding. The main focus …
Protein Folding, Misfolding and Aggregation
Classical Themes and Novel Approaches
Av Victor Muñoz
Inbunden, 2008
2453 kr
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Protein folding and aggregation is the process by which newly synthesized proteins fold into the specific three-dimensional structures defining their biologically active states. It has always been a major focus of research in biochemistry and has often been seen as the unsolved second part of the …
Protein-Nucleic Acid Interactions
Structural Biology
Av Phoebe A Rice, Carl C Correll
Inbunden, 2008
2588 kr
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The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid 1980s and a vast array of such structures has now been determined, but surprising and novel …
Metabolomics, Metabonomics and Metabolite Profiling
Inbunden, 2007
2453 kr
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The completion of gene sequencing has resulted in an intensified investigation of the proteome and metabolome. Metabolite profiling methods used for disease diagnosis have been expanded with the advent of new technology and are being applied extensively in the quest for the discovery of new markers …
Structure-Based Drug Discovery
An Overview
Inbunden, 2006
2453 kr
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Structure-based drug discovery is a collection of methods that exploits the ability to determine and analyse the three dimensional structure of biological molecules. These methods have been adopted and enhanced to improve the speed and quality of discovery of new drug candidates. After an …
Computational and Structural Approaches to Drug Discovery
Ligand-Protein Interactions
Av Robert Stroud, Janet Finer-Moore
Inbunden, 2007
2673 kr
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Computational methods impact all aspects of modern drug discovery and most notably these methods move rapidly from academic exercises to becoming drugs in clinical trials... This insightful book represents the experience and understanding of the global experts in the field and spotlights both the …
Biophysical Approaches Determining Ligand Binding to Biomolecular Targets
Detection, Measurement and Modelling
Av Alberto Podjarny, Annick P Dejaegere m. fl.
Inbunden, 2011
2426 kr
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The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the …
DNA Conjugates and Sensors
Av Keith R Fox, Tom Brown
Inbunden, 2012
2806 kr
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Applications of nucleic acids have developed recently to provide solutions for biosensors, diagnostic tools and as platforms for the assembly of complex structures. These developments have been possible as their base sequence can be used to assemble precise structures following simple and …
Innovations in Biomolecular Modeling and Simulations
Volume 1
Inbunden, 2012
2806 kr
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The chemical and biological sciences face unprecedented opportunities in the 21st century. A confluence of factors from parallel universes - advances in experimental techniques in biomolecular structure determination, progress in theoretical modeling and simulation for large biological systems, and …
Nucleic Acid-Metal Ion Interactions
Inbunden, 2008
2193 kr
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Natural biochemical processes are routinely being discovered in living cells that involve RNA. Some of these processes, such as RNA interference, are now being exploited for biotechnology and medicinal applications. DNA has also proven in recent years to be more than a passive storehouse of …
Biophysical and Structural Aspects of Bioenergetics
Inbunden, 2005
2193 kr
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Bioenergetics is a term used to describe the events of primary energy transduction in biology. The field has seen tremendous advances in recent years thanks to developments in the biophysical and computational techniques used to solve the three-dimensional structures of the membrane-bound proteins, …
Structural Biology of Membrane Proteins
Av Reinhard Grisshammer, Susan K Buchanan
Inbunden, 2006
2193 kr
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In the last few years there have been many exciting and innovative developments in the field of membrane protein structure and this trend is set to continue. Structural Biology of Membrane Proteins is a new monograph covering a wide range of topics with contributions from leading experts in the …
Sequence-specific DNA Binding Agents
Inbunden, 2006
2012 kr
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The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the subject. Written …
Quadruplex Nucleic Acids
Av Stephen Neidle, Shankar Balasubramanian
Inbunden, 2006
2012 kr
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Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood. Recent advances have demonstrated that quadruplex structures can play a role in gene expression and provide opportunities for a new class of anticancer therapeutics. A …
Protein-Carbohydrate Interactions in Infectious Diseases
Inbunden, 2006
2258 kr
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Protein-carbohydrate interactions is an exciting area of research with huge potential for development and exploration. These interactions are both widespread and diverse in biological processes and many play a crucial role in cellular recognition, attachment and adhesion. This is particularly true …
Exploiting Chemical Diversity for Drug Discovery
Av Paul A Bartlett, Michael Entzeroth
Inbunden, 2006
2145 kr
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Conceptual and technological advances in chemistry and biology have transformed the drug discovery process. Evolutionary pressure among the diverse scientific and engineering disciplines that contribute to the identification of biologically active compounds has resulted in synergistic improvements …
Biomolecular Sciences Series Set
2005 - 2012
2015
55760 kr
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A collection of books edited and written by leading international scientists working in the field, the RSC Biomolecular Sciences Set provides an authoritative and definitive collection of reference guides for graduate and postgraduate students and researchers in biochemisty, biophysics and …
RNA Helicases
Inbunden, 2010
1912 kr
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RNA helicases and RNA helicase-like proteins are the largest group of enzymes in eukaryotic RNA metabolism and although they are subject to intense ongoing research there is much confusion about function and classification of these enzymes. Although these enzymes are essential for virtually all …
Recent Developments in Biomolecular NMR
Av Marius Clore, Jennifer Potts
Inbunden, 2012
2328 kr
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NMR spectroscopy is widely used in biomolecular science particularly for structure determination of proteins, nucleic acids and carbohydrates. Much of the innovation within NMR spectroscopy has been within the field of protein NMR spectroscopy, an important technique in structural biology. Filling …
Innovations in Biomolecular Modeling and Simulations
Complete Set
2012
4629 kr
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The chemical and biological sciences face unprecedented opportunities in the 21st century. A confluence of factors from parallel universes - advances in experimental techniques in biomolecular structure determination, progress in theoretical modeling and simulation for large biological systems, and …
Innovations in Biomolecular Modeling and Simulations
Volume 2
Inbunden, 2012
2746 kr
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The chemical and biological sciences face unprecedented opportunities in the 21st century. A confluence of factors from parallel universes - advances in experimental techniques in biomolecular structure determination, progress in theoretical modeling and simulation for large biological systems, and …
