Neurological Complications of Systemic Cancer and Antineoplastic Therapy

Herbert B. Newton Dr. Newton is currently the Director of the Neuro-Oncology Center and Brain Tumor Institute at the University Hospitals of Cleveland Medical Center and Seidman Cancer Center. He holds the William B. Risman Endowed Chair for Memory and Cognition. He retired as a Professor of neurology and neurosurgery at the Ohio State University Medical Center and the James Cancer Hospital, and was the holder of the Esther Dardinger Endowed Chair in Neuro-Oncology. He trained in neuro-oncology with Drs. Jerome Posner and William Shapiro at Memorial Sloan Kettering Cancer Center in New York and has been in academic neuro-oncology for over 30 years. He has published more than 230 peer-reviewed articles and book chapters and is the Chief Editor or Co-Editor of 13 textbooks in the field of neurology and neuro-oncology. In addition, he has been listed as a Best Doctor (neurology) and Top Doctor for cancer (neuro-oncology) for the past 23 years . Dr. Malkin is currently the Director of the Neuro-Oncology Program at Massey Cancer Center, and Director of the Neuro-Oncology Division, in the Department of Neurology at Virginia Commonwealth University School of Medicine. He holds the William G. Reynolds, Jr. Chair in Neuro-Oncology and is Professor of Neurology. Before his appointment at VCU, he was the Director of Neuro-Oncology and Professor of Neurology at Froedtert and the Medical College of Wisconsin. Prior to his move to Milwaukee, he was an Associate Clinical Member at Memorial Sloan-Kettering Cancer Center and Associate Clinical Professor of Neurology at Weill Cornell Medical College. He also trained in Neuro-Oncology with Drs. Jerome Posner and William Shapiro at Memorial Sloan-Kettering Cancer Center, and since then has been in academic Neuro-Oncology for over 33 years. He has published more than 100 peer-reviewed articles and book chapters and is Co-Editor of several textbooks in the field of Neuro-Oncology.

• SECTION I. Metastatic Neurological Complications1. Common symptoms at presentation of nervous system metastases2. Neuroimaging of systemic metastatic disease3. Nonimaging evaluation of patients with nervous system metastases4. Biology and pathophysiology of central nervous system metastases5. Intracranial metastases6. Neurosurgical approaches to the treatment of intracranial metastases7. Epidural metastasis and spinal cord compression8. Leptomeningeal metastasis9. Cranial nerve involvement by metastatic cancer10. Cancer-related plexopathiesSECTION II. Nonmetastatic Neurological Complications11. Cerebrovascular complications of malignancy12. Metabolic and nutritional nervous system dysfunction in cancer patients13. Central nervous system infections in cancer patients14. Diagnosis and treatment of paraneoplastic neurological disordersSECTION III. Neurological Complications of Specific Neoplasms 15. Neurological complications of lung cancer16. Neurological complications of breast cancer17. Neurological complications of melanoma18. Neurological complications of lymphoma19. Neurological complications of the leukemias20. Neurological complications of systemic cancer of the head and neck                                                              21. Neurological complications of gynecological cancers22. Neurological complications of GI cancers23. Neurologic complications associated with genitourinary cancer24. Sarcoma and the nervous system25. Neurological complications of multiple myeloma26. Neurologic complications in the treatment of childhood malignanciesSECTION IV. Neurological Complications of Antineoplastic Therapy27. Neurological complications of radiation therapy28. Neurological complications of systemic cancer and antineoplastic therapy29. Neurological complications of hematopoietic stem cell transplantation30. Chemotherapy-induced peripheral neuropathy31. Neurological complications of immunotherapy and monoclonal antibody therapy32. Neurological complications of immune modulatory therapy33. Neurological complications of steroids and of supportive careSECTION V. Psychiatric, Pain, Psychosocial, and Supportive Care Issues 34. Psychiatric aspects of care in the cancer patient35. Chronic cancer pain syndromes and their treatment36. Psychosocial issues in cancer patients with neurological complications37. Supportive care