...a very well-written book [that] provids a wealth of very interesting and useful information on a rapidly evolving and clinically relevant field, in which there is still a huge unmet need for effective analgesics.

• 1. Molecular biology of nociceptors ; 2. Nociceptor plasticity ; 3. Molecular architecture of the dorsal horn ; 4. Cellular and molecular mechanisms of central sensitization ; 5. Mechanisms of peripheral neuropathic pain ; 6. Targets in pain and analgesia ; 7. The ascending pain pathways ; 8. Spinal delivery of drugs in pain control ; 9. The development of pain systems ; 10. Visceral and deep somatic pain ; 11. The organization of the midbrain periaqueductal grey matter and the integration of pain behaviours ; 12. Descending control of pain processing ; 13. Central imaging of pain ; 14. Headache ; 15. An integrative approach to the control of cancer pain

...a very well-written book [that] provids a wealth of very interesting and useful information on a rapidly evolving and clinically relevant field, in which there is still a huge unmet need for effective analgesics.

• 1. Molecular biology of nociceptors ; 2. Nociceptor plasticity ; 3. Molecular architecture of the dorsal horn ; 4. Cellular and molecular mechanisms of central sensitization ; 5. Mechanisms of peripheral neuropathic pain ; 6. Targets in pain and analgesia ; 7. The ascending pain pathways ; 8. Spinal delivery of drugs in pain control ; 9. The development of pain systems ; 10. Visceral and deep somatic pain ; 11. The organization of the midbrain periaqueductal grey matter and the integration of pain behaviours ; 12. Descending control of pain processing ; 13. Central imaging of pain ; 14. Headache ; 15. An integrative approach to the control of cancer pain