Computational and Statistical Approaches to Genomics

AvIlya Shmulevich,Wei Zhang

E-bok
PDF, Engelska, 2007

1 132 kr

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Beskrivning

Computational and Statistical Genomics aims to help researchers deal with current genomic challenges. Topics covered include:

  • overviews of the role of supercomputers in genomics research, the existing challenges and directions in image processing for microarray technology, and web-based tools for microarray data analysis;
  • approaches to the global modeling and analysis of gene regulatory networks and transcriptional control, using methods, theories, and tools from signal processing, machine learning, information theory, and control theory;
  • state-of-the-art tools in Boolean function theory, time-frequency analysis, pattern recognition, and unsupervised learning, applied to cancer classification, identification of biologically active sites, and visualization of gene expression data;
  • crucial issues associated with statistical analysis of microarray data, statistics and stochastic analysis of gene expression levels in a single cell, statistically sound design of microarray studies and experiments; and
  • biological and medical implications of genomics research.

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