Springer US – förlag

Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT).

The Rise and Fall of Epithelial Phenotype is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural crest cell migration and heart morphogenesis in vertebrates. Part two reviews in detail, specific EMT molecular pathways covering extracellular induction, transduction and transcription response and modulation of cell-cell adhesion structures. It emphasizes new specific pathways with potential medical applications. EMTs can also be linked to pathological events such as wound healing and cancer progression, as detailed in this section of the book.

Since the pioneering work of Black, Scholes, and Merton in the field of financial mathematics, research has led to the rapid development of a substantial body of knowledge, with plenty of applications to the common functioning of the world’s financial institutions.

Mathematics, as the language of science, has always played a role in the development of knowledge and technology. Presently, the high-tech character of modern business has increased the need for advanced methods, which rely to a large extent on mathematical techniques. It has become essential for the financial analyst to possess a high degree of proficiency in these mathematical techniques.

Optimization problems are widespread in the mathematical modeling of real world systems and their applications arise in all branches of science, applied science and engineering. The goal of the Encyclopedia of Optimization is to introduce the reader to a complete set of topics in order to show the spectrum of recent research activities and the richness of ideas in the development of theories, algorithms and the applications of optimization. It is directed to a diverse audience of students, scientists, engineers, decision makers and problem solvers in academia, business, industry, and government.

Quantitative Corporate Finance is designed to be an advanced graduate corporate financial management textbook. The book will address several problems in contemporary corporate finance: optimal capital structure, both in the US and in the G7 economies, the Capital Asset Pricing Model (CAPM) and the Arbitrage Pricing Model (APT) and the implications for the cost of capital, dividend policy, sales forecasting and pro forma statement analysis, leverage and bankruptcy, and mergers and acquisitions.

Microstructured Polymer Optical Fibres describes the optical properties of microstructured fibres, how they are made and modelled, and outlines some potential applications. These applications include areas where polymer fibres are already used, such as high-data rate transmission for Fibre-to-the Home or within cars, as well as completely new areas such as the photonic bandgap transmission of "difficult" wavelengths.

Emphasising a conceptual understanding of the underlying physics, Microstructured Polymer Optical Fibres is clearly written, and includes numerous illustrations. It provides an excellent overview of the latest developments in the field, making them accessible to industry, technical and research audiences.