Anticandidal Therapeutics

Discovery and Development

AvAwanish Kumar,Anubhuti Jha

Häftad, Engelska, 2023

Del i serien Developments in Microbiology

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Beskrivning

Developments of antifungal agents have declined as compared to other antibiotics that have displayed a potent development with time. There is an urgent need for both prophylactic and therapeutic treatments worldwide to control the severity of infections caused by Candida. Anticandidal Therapeutics: Discovery and Development provides the readers with a compiled knowledge of the fungal human infection Candida and the development of anticandidal drugs. Anticandidal Therapeutics helps researchers form the basis for the discovery and development of novel anticandidal therapies. In 14 chapters this book provides collective information on anticandidal agents and their discovery and development with respect to major drug transporter families, different stages of anticandidal agent development, recent trends and progress in antifungal translational research, clinical studies status of anticandidal therapeutic agents, and drug repurposing for development of novel anticandidal agents.

Highlights the mechanistic actions of some therapeutic agents against Candida
Focuses on anticandidal agents rather than general antifungal agents
Discusses the stage of development of new antifungal drugs, the repositioning of drugs, and how this could help in treatment

Produktinformation

Utgivningsdatum:2023-01-23
Mått:191 x 235 x 16 mm
Vikt:450 g
Format:Häftad
Språk:Engelska
Serie:Developments in Microbiology
Antal sidor:196
Förlag:Elsevier Science
ISBN:9780443187445

Utforska kategorier

Svampböcker inom Djur och Natur
Svampar inom Naturvetenskap och teknik

Mer om författaren

Dr. Awanish Kumar is an Associate Professor of the Department of Biotechnology at the National Institute of Technology, Raipur, Chhattisgarh, India. He has more than 13 years of research experience. He received his PhD in molecular parasitology from the CSIR-Central Drug Research Institute, Lucknow, India, and Jawaharlal Nehru University, Delhi, India, and completed his postdoctoral studies at McGill University, Montreal, Canada. His research interests are infection biology, drug targeting, and drug discovery. Dr. Anubhuti Jha works in the area of antifungal drug discovery. She has obtained PhD degree from Department of Biotechnology, National Institute of Technology, Raipur (CG), India. She has published more than 15 research paper in peer_x0002_reviewed journals and has authored several books/chapters.

Innehållsförteckning

1. History of infection2. Brief introduction on infection3. Fungal diseases and antifungal drugs4. Multidrug transporters of fungal pathogen Candida5. Essential anticandidal targets6. Stages of anticandidal agent development7. Recent trends and progress in antifungal translational research8. Clinical status of anticandidal therapeutic agents9. Drug repurposing for development of effective anticandidals10. Commercial aspects of drug development11. Challenges and future prospects