Developments in Microbiology – serie

Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for application in therapeutics with diagnostic applications. The book focuses on the theranostic applications of nanomaterials in infectious diseases, highlighting that rapid diagnosis, safe and effective treatment and strong preventive measures like vaccines are urgently needed. It compiles all relevant information to help scientists, researchers and students understand the role of nanomaterials, how nanomaterials could be explored simultaneously for therapeutic and diagnostic applications, and how to ensure safety and efficacy of these nanomaterials.

Sections cover fundamental concepts, emerging concerns and challenges to combat infectious diseases, the characterization of nanomaterials for theranostic applications, and the toxicity, biocompatibility and regulatory perspectives in the diagnosis and treatment of infectious diseases.

Compiles the latest information on the technological advancements made in the field of nanotechnology for applications in therapeutics Prepares researchers to get ready to fight any emergency which may arise due to the advent of infectious diseases Focuses on the theranostic applications of nanomaterials in infectious diseases Compiles all relevant information to help scientists, researchers and students in understanding the role of nanomaterials and how they could be explored for therapeutic and diagnostic applications

Expanding Horizon of Cyanobacterial Biology discusses the different aspects of cyanobacteria cyanobacterial application, providing a better understanding of cyanobacterial metabolism. Chapters deal with cyanobacteria applications and explore how to exploit cyanobacterial metabolism for industrial applications. Sections cover cyanobacterial applications for the production of nanoparticles, cyanobacterial diversity, and the characterization of different assemblages such as cyanolichens and cyanobacterial endophytes, along with their ecological, morphological and physiological aspects. In addition, bioactive compounds and their applications are explored.

Increasing attention has been paid by scientists across the globe to Cyanobacteria as they are ubiquitous microbes and, undoubtedly, an important organism in terms of carbon as well as nitrogen fixation. However, the research on these organisms is limited in terms of their diversity and distribution across the globe.

Provides background knowledge for researchers concerned with cyanobacterial diversity and characterization of different assemblages Describes the exploitation possibility of cyanobacterial species for human welfare Discusses the different aspects of cyanobacteria, cyanobacterial application and better understanding of cyanobacterial metabolism Deals with the exploitation of cyanobacteria and their mats for bioremediation purposes Includes cyanobacterial nanotechnology and its applications in industry and allied sectors

Human-Gut Microbiome: Establishment and Interactions gives an overview of microbiome establishments in humans and basic technologies used to decipher the structure and function of gut microbiome. Other sections focus on the application of microbiomics in different disease manifestations, such as obesity, diabetes, and more. The book provides the basics, as well as mechanistic knowledge underpinning the structural and functional understanding of the microbiome. With the advancement in omics technologies, as well as the development of bioinformatic tools, much research has been undertaken to decipher the microbiomes of different hosts.

This research is generating valuable insights into micro-ecological niches and their impact on humans, hence this new release covers these new insights. The book will be a valuable resource for scientists, researchers, postgraduate and graduate students who are interested in understanding the impact and importance of the omics approach to humans and their microbiomes.

Provides an overview of the recent developments in meta-omics technologies Serves as a unique reference for healthcare professionals, pursuing research on gut homeostasis, and functional foods, as well as nutritional dietary management Focuses on the application of microbiomics in different disease manifestations, such as obesity, diabetes, and more

Immunopathology, Diagnosis and Treatment of HPV induced Malignancies focuses on the human papilloma virus infection and associated cancers. In ten chapters, the book explains the deep knowledge about molecular mechanism in HPV pathogenesis and recent advanced tools applied in the field of HPV induced cancer and cures. In a nutshell, the book gives new insights and the associated challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancers and other malignancies. Highlights the concept of Human papilloma virus infection, its pathogenesis, mechanisms involved in host immune response, clinical manifestations, prophylactic and therapeutic strategies, and recent advancements for the cure of HPV induced cancer Delineates new insights and challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancer Provides comprehensive and conceptual knowledge that could be a milestone not only in the field of infectious cancers but also for researchers and scientists working on infectious cancer

Biology of Mycobacterial Lipids covers various topics pertaining to the advancements and current research in the field of mycobacterial lipids, and on the significant progress in lipidomics, in recent times. The chapters present comprehensive, yet systematic cutting-edge research, comprising mycobacterial lipid terminologies, classifications, biosynthetic pathways, tools and techniques, and functional burgeoning. This unique reference book has contributions from pioneer researchers, experts, and eminent veterans from around the globe. It covers ground-breaking work that will bridge the gap between understanding biochemical patterns related to virulence, pathogenesis, and resistance and elucidating new targets for drug design, identifying biomarkers for predicting risk, early diagnosis, and therapeutic outcome.

Covers major biochemical aspects of mycobacterial lipids, nomenclature, structure and classification, and metabolic pathways Focuses on recent trends and state-of-the-art technology, used in mycobacterial lipids study Brings together the functional aspects of mycobacterial lipidome, involvement of lipids in cellular network and signaling, its involvement in virulence and resistance, and host factor manipulations Highlights the discovery of lipid biomarkers, for diagnostic and therapeutic interventions, using mycobacterial lipidomic studies Presents lipids at the interface of various other biomolecules with integrative omics aspects

Laboratory Methods in Microbiology and Molecular Biology describes various microbiological, biochemical, and molecular methods employed for the characterization, identification, and analysis of actinomycetes, bacteria and fungi. The book details general guidelines, expectations, and responsibilities for good lab practices and consists of chapters that covers basic microbiological, physiological, biochemical, and molecular aspects as well as in silico analysis using various bioinformatic tools. Other topics in the book include how to make solutions, microscopy and imaging of microorganisms, sero-diagnostics, and basic concepts of phylogeny, physiology, biotechnology, soil, food, and environmental microbiology while working in laboratory. Laboratory Methods in Microbiology and Molecular Biology is an informative update to current practices and future perspectives for the field of microbial biotechnology. It aims to facilitate professors, researchers, and graduate students in monitoring the precision and accuracy of the qualitative and quantitative methods in their research.

Involves various procedures in diverse disciplines, from microbiology to genetics, molecular biology and biochemistry Lists the principles and facts underlying practical applications of bacteria and fungi which have prospects in various technologies Includes the questions 'how' and 'why' as an explanation for novice students and researchers to modify protocols Facilitates students, teachers and researchers to monitor the precision and accuracy of their qualitative and quantitative methods practically

Organ-Specific Parasitic Diseases of Dogs and Cats takes an organ-specific approach to the impact of parasitic diseases in dogs and cats. This book provides a detailed description of the key role that parasites play in the pathogenesis of diseases, explores the manifestation of symptoms and diagnosis, and offers prevention and treatment strategies to counteract parasitic infections.

An introduction by the editor is followed by chapters from various authors covering parasitic diseases in specific organs and organ systems. The book also provides an overview on the diagnostic evaluation of parasitic diseases. Parasite control, travel management, therapeutic measures, and disease control strategies round out the discussion.

With contributions from experts in the field, this book serves as a useful resource to researchers, academics, and postgraduates who wish to expand their knowledge on parasitic diseases, diagnosis, and treatment, and as a reference for scientists looking to develop new antiparasitic drugs.

Provides a systematic overview of the pathogenesis of parasites in dogs and cats Evaluates parasitic diseases and their pathogenesis in specific organs Identifies pathogens and their role in the severity of disease manifestation Explains therapeutic strategies to combat parasitic diseases in dogs and cats Offers preventive and treatment strategies to counteract the etiopathogenesis caused by various types of parasites

Antibiotics: Therapeutic Spectrum and Limitations provides up-to-date information on managing microbial infections, the development and types of antibiotics, the rationale for utilizing antibiotics, toxicity considerations, and the control of antibiotic resistance in one single resource. This book also aims to provide comprehensive insights and current trends on antibiotic therapies to treat microbial infections, their mechanisms of action, and the role of modern drug delivery in improving their efficacy. Written by leading experts from around the globe, the chapters in the book covers important aspects of microbial infections including hospital acquired infections and community acquired infections and adult sepsis, examines the various types of antibiotics with different mechanisms and therapeutic uses, the global challenge of antibiotic resistance, and clinical trials, regulatory considerations, and market overview of antibiotics. Furthermore, the chapters include updated literature reviews of the relevant key topics, high-quality illustrations, chemical structures, flowcharts, and well-organized tables, all of which enable better understanding by the readers.

Provides in-depth and updated information and analyses on microbial infections, antibiotics and therapeutics, the consequences of antibiotic resistance, and the role of modern drug delivery in improving efficacyDiscusses different types of antibiotics and their mechanisms as well as traditional medicine, herbal drugs, and postbiotics in the treatment and prevention of microbial infections and management of antibiotic resistanceContributed by global leaders and experts from academia, industry, research institutes, and regulatory agencies

Application and utilization of data science approaches has revolutionized scientific research including host-pathogen interaction analyses. Host-pathogen interactions are generally considered highly specific interactions, resulting in a variety of consequences. Data science approaches coupled with network biology has taken host-pathogen interaction analysis from specific interaction to a new paradigm of understanding the consequences of these interactions within a biological network. Unfortunately, basic biological researchers are mostly unaware of these advancements. Conversely, data scientists are not familiar with biological aspects of such data.Systems Biology Approaches for Host-Pathogen Interaction Analyses benefits biological researchers by expanding the scope of their research and utilization of their accumulated data using recent technological advancements. In addition, the book also opens avenues for bioinformatics and computer science researchers to utilize their expertise in biologically meaningful ways.

Cover approaches to decipher complex multiple host-pathogen interactionsGives biological researcher an insight into the utilization of technological advancements in the field of host-pathogen interaction analyses in their workProvides a new paradigm of understanding the consequences of host-pathogen interaction in biological systems

Considering the global emerging human pathogenic microbial diseases and trends, Human Pathogenic Microbes is framed to provide deep insights into the epidemic and emerging bacterial and fungal infections and diseases in humans. It presents novel, up-to-date, and cutting-edge knowledge regarding various human pathogenic microbes, their associated drug resistance mechanisms, and different diseases caused by them.

Human Pathogenic Microbes reflects the current research and development on the evolution of bacterial and fungal drug resistance: different bacterial and fungal antimicrobial drug resistance mechanisms along with their biological and molecular aspects.

In a nutshell, Human Pathogenic Microbes describes a various bacterial and fungal diseases caused by different human pathogenic microbes employing different drug resistance mechanisms and processes. It also highlights the novel emerging approaches (Immunological and combinatorial) that will aid to fight against such bacterial and fungal pathogens.

Provides a brief but thorough and recent knowledge of various human pathogenic microbes, their associated drug resistance mechanisms, and different diseases caused by them Describes the different aspects of fungal, bacterial and antimicrobial resistance Addresses novel antimicrobial agents and approaches

The excessive use of antibiotics has given rise to an increase in microbial resistance, threatening our ability to treat infectious diseases. The growth in resistance to antimicrobials and antibiotics threatens to reverse almost a century of medical progress. urgent action plans to tackle the crisis of Antimicrobial Resistance (AMR) and multi-resistant bacteria are needed.

It is a major research task to find effective ways to reduce the release and degradation of antibiotics and ARBs to the environment. Degradations of Antibiotics and Antibiotic Resistance Bacteria from various sources addresses various issues related the generations and degradations, eliminations of antibiotics and antibiotics resistance bacteria.

Degradations of Antibiotics and Antibiotic Resistance Bacteria from various sources contains both practical and theoretical latest and broad aspects of antibiotics and antibiotics resistance bacteria management through the various recent methods. Various factors which are responsible for the efficient degradations are highlighted in the Degradations of Antibiotics and Antibiotic Resistance Bacteria from various sources as separate chapters. Socioeconomic and policies on the ARBs are also discussed.

Contains both practical and theoretical latest and broad aspects of antibiotics resistant bacteria Emphasizes the health impact of antibiotic resistance and genes Gives insight in the applications of anaerobic digestions for eliminations of ARBs (antibiotic resistance blockers) and ARGs (Antibiotic Resistance Genes) Shows how ARB's influences the degradation processes and management

The Microbiology, Pathogenesis, and Zoonosis of Milk Borne Diseases offers comprehensive coverage of milk-borne infection, diagnosis, and treatment. With a strong focus on milk hygiene, zoonotic diseases, and the pathogenesis of milk-borne microbial agents, this book discusses various pathogenic diseases, evaluates the severity of diseases from milk and milk products, and describes remedial measures after the application of drugs.This book also introduces the reader to the microbiology, pathogenesis, and zoonosis of milk-borne diseases. It not only describes the general aspects of milk-borne zoonosis and prevention, but also covers risk analysis, assessment, practice, and quality management in milk hygiene.In 22 chapters, The Microbiology, Pathogenesis, and Zoonosis of Milk Borne Diseases provides researchers, academicians, industry professionals, and students with a better understanding on how to assess zoonotic diseases from milk-borne pathogens and address their clinical manifestations.Emphasizes the importance of milk hygiene to prevent milk-borne diseasesProvides an overview of milk borne diseases, diagnosis, and treatmentIdentifies the various milk-borne zoonotic pathogens and their impact on public health

Introduction to Diseases, Diagnosis, and Management of Dogs and Cats offers an informative and practical resource for an in-depth understanding of the full range of clinical and infectious diseases that occur in dogs and cats. It provides systematic coverage on the pathogenesis of disease, disease manifestation, diagnosis, treatment, therapeutic management, and prevention.Organized into three main sections, the book begins with an overall introduction and general discussion on the diagnosis and management of clinical and infectious diseases. This section examines the biological systems of dogs and cats, covers clinical examinations and diagnosis methods, specimen collection, nutritional strategies, and health maintenance. Section 2 goes on to discuss a range of clinical diseases that can affect the health of dogs and cats which includes diseases that impact major systems in the body like the cardiovascular, respiratory, gastrointestinal, reproductive, endocrine, nervous, and urinary systems to name a few. It also delves into autoimmune conditions, behavioral orders, and common toxicological phenomenon that occur in dogs and cats and offers strategies for pain management and therapeutic drug intervention. Section 3 rounds out the book with coverage of bacterial, fungal, viral, and parasitic infectious diseases. It explains the pathogenesis of disease, evaluation of the disease, identification of the pathogens and their severity to animals, disease manifestation in the animal, and preventive and treatment strategies to counteract the etiopathogenesis caused by several types of pathogens.With contributions from experts in the field, Introduction to Diseases, Diagnosis, and Management of Dogs and Cats features the latest advanced veterinary research for researchers, clinicians, and students engaged in researching and treating diseases in dogs and cats.Discusses clinical diseases of dogs and cats including those that impact major systems in the body, specimen collection, clinical examination, diagnosis, and medical interventionsCovers the etiology and epidemiology, physical examination abnormalities, pathogenesis, clinical signs, diagnosis, treatment and prognosis, immunity and vaccination, and prevention of infectious diseasesExplores advances in diagnosis and treatment including molecular diagnostic techniques and therapies

Infectious Diseases: Smart Study Guide for Medical Students, Residents, Physicians and Clinical Pharmacists�attempts to consolidate knowledge and information into a step-by-step process that would be easy to understand, remember, and apply in a clinical setting. High-yield information presented in this book is necessary for medical students and residents. This book has provided information for all disciplines working in infectious diseases, whether students, residents, physicians, pharmacists, or nurses. The book is organized for quick and easy to retrieve information for all professionals.

Medical and pharmacotherapeutic information about infectious diseases are combined into one book Consolidates knowledge and information on infectious diseases Presents content that is easy to understand, remember, and apply in a clinical setting High-yield information for students and residents

Developments of antifungal agents have declined as compared to other antibiotics that have displayed a potent development with time. There is an urgent need for both prophylactic and therapeutic treatments worldwide to control the severity of infections caused by Candida. Anticandidal Therapeutics: Discovery and Development provides the readers with a compiled knowledge of the fungal human infection Candida and the development of anticandidal drugs. Anticandidal Therapeutics helps researchers form the basis for the discovery and development of novel anticandidal therapies. In 14 chapters this book provides collective information on anticandidal agents and their discovery and development with respect to major drug transporter families, different stages of anticandidal agent development, recent trends and progress in antifungal translational research, clinical studies status of anticandidal therapeutic agents, and drug repurposing for development of novel anticandidal agents.

Highlights the mechanistic actions of some therapeutic agents against Candida Focuses on anticandidal agents rather than general antifungal agents Discusses the stage of development of new antifungal drugs, the repositioning of drugs, and how this could help in treatment

Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health.Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.

Fulfills the knowledge gap in biofilm studyFocuses on new and emerging concepts in microbial biofilm researchHighlights the various anti-biofilm strategiesProvides concise, thorough and up-to-date information about the important role of microbial biofilms in human diseases

Salmonella Biofilms, Infection, and Therapeutic Management provides an overview of salmonella biofilms, their detection and identification, associated salmonellosis infection, prevention and treatment.The book discusses salmonella, the formation of biofilm, and biofilm associated bacterial infection. It aims to provide insight on how salmonellosis and biofilm relate to one another as well as how they relate to other diseases in the host. It also discusses the therapeutic strategy for reducing salmonella infection and current treatment options. Salmonella Biofilms, Infection, and Therapeutic Management is a useful reference for those engaged in the study of the study of salmonella biofilm, its formation, disease manifestation, and management.

Provides the most recent knowledge on salmonellosis and its relationship to biofilmDescribes different types of salmonella bacteria and biofilm as well as the regulatory and virulence mechanisms of salmonellaExamines the mechanisms of Salmonella biofilm formation and the relationship between this and other aspects of Salmonella physiology

ESKAPE Pathogens: Virulence, Resistance, and Management provides comprehensive coverage on ESKAPE pathogens, including their virulence mechanisms, resistance patterns, and challenges in their management. The book offers the latest information on ESKAPE pathogens' pathogenicity, mechanisms of antibiotic resistance, and innovative approaches to manage these pathogens. It explores recent advancements in the field of genomics, proteomics, and transcriptomics that could potentially provide valuable insights into the mechanisms and genetic basis of antibiotic resistance in ESKAPE pathogens. Finally, the book highlights the need for alternative treatment options and innovative management strategies to combat the emergence of multidrug-resistant strains.This is a helpful resource to researchers, clinicians, educators, industry professionals, and advanced students interested in the latest research and strategies for combating multidrug-resistant pathogens.Offers practical guidance on identifying and managing infections caused by ESKAPE pathogens, including diagnosis, treatment, and preventionDiscusses the latest research on management strategies to combat ESKAPE pathogensExplores novel therapeutic approaches and prevention strategies for infections caused by ESKAPE pathogens

Microbial Stress Survival explores the diversity of microbes, the microbe-host relationship, and the various strategies employed by microbes that enable them to adapt to stressful environments and persist in hostile conditions. The book aims to cover critical pathogen biology, microbial adaptation and survival strategies, and the impact of microbial resilience on therapeutic efforts. Topics include the modulation of host pathways by pathogens for their adaptation and survival; their drug tolerance and antimicrobial resistance; role of proteins in microbial stress survival; and evolutionary adaptative mechanisms of extremophiles. Microbial Stress Survival is an insightful resource for those interested in pathogen biology and the different adaptive features and resilience of microbes.Discusses the adaptive mechanisms of microbes that allow them to cross the defensive barrier of their hostCovers the proteins responsible for growth regulation of bacteria during unfavorable conditionsExamines microbial stress response and adaption to extreme environmentsExplores different bioremediation strategies for the degradation of various types of pollutants

Applications of Nanotherapeutics and Nanotheranostics in Managing Infectious Diseases discusses how nanotechnology aids in overcoming the existing traditional approaches in combating diseases. The book explores the emerging trends of using nanoparticles for nanotherapeutics and nanotheranostics and their role in the efficient diagnosis and treatment of infectious microbial diseases. Sections covers nanotherapeutic impregnated medical devices, nanotherapeutics as vaccines, related regulatory requirements, the application of nanotherapeutics and nanotheranostics in diagnosing and treating specific infectious diseases, including bacterial infections, viral infections, fungal infestations, parasitic infestations, and other infectious conditions.With chapter contributions from experts in the fields, this book offers a comprehensive reference for researchers, scientists, and industry professionals working on infectious diseases and the application of nanoparticles to effectively diagnose, treat, and manage them.Discusses the mechanisms behind the enhanced therapeutic potential of using nanomaterial as an efficient drug delivery system to meet the challenges of combating various complex diseasesEmphasizes the recent advances in interdisciplinary research on processing, morphology, structure, and properties of nanostructured materials and their applications in the treatment of infectious diseasesCovers different types of nanoparticles, their role in drug delivery and the latest updates in regulatory requirements, patents, clinical trials, and commercial flexibility

Antimicrobial Resistance in Humans, Animals, and the Environment: One Health Approach examines the global impact of antimicrobial resistance (AMR) with a specific focus on the interconnectedness between animal, human, and environmental health. The book details the origin, evolution and ecology of AMR and its updated epidemiology. It discusses the transmission of antimicrobial resistance between humans, animals, and the environment. It delves into the molecular mechanisms of drug resistance development and epidemiology in human and animal health; the different challenges in treating antimicrobial-resistant infections including rapid diagnosis and the development of new antimicrobial agents; and alternative strategies treating drug-resistant infections. Antimicrobial Resistance in Humans, Animals, and the Environment: One Health Approach is a useful comprehensive resource for researchers, academics postgraduate students, PhD students, early career researchers, and medical scientists in microbiology, infectious diseases, and biotechnology, public health professionals, clinical personnel treating AMR, or policymakers interested in implementing antimicrobial stewardship program in hospitals.Discusses antimicrobial resistance across the microbial kingdoms of bacteria, fungi, viruses, and protozoa and details the molecular mechanisms of resistance development in microbesExamines the link Between the environment, such as climate change, industrialization, and heavy metal pollution, and the rise of resistant microbesOffers alternative strategies to tackling AMR and the treatment of drug-resistant infections