Cold-Adapted Enzymes

Dr. Diego Gomez-Casati is a senior academic and research scientist at the Centre for Photosynthetic and Biochemical Studies and Professor of Chemical Biology at the National University of Rosario, Argentina. He is PI of the Plant and Algae Molecular Biology and Biotechnology Laboratory and Vice-Director. Dr. Gomez Casati has a PhD in Biochemistry from the University of Buenos Aires. He was a visiting scientist at California State University, Fullerton, USA, Laboratoire Microbiologie Cellulaire et Moleculaire et Pathogenicite, Centre National de la Recherche Scientifique (CNRS), Université Bordeaux-2 and Pontificia Universidad Católica de Chile. He was also Professor of Plant Biotechnology at the National University of San Martín (UNSAM). Dr. Gomez-Casati’s research interests include the study of the structure, function and regulation of polysaccharide metabolism enzymes and their biotechnological applications. He has published over 85 research papers, reviews and book chapters, most related to the biochemical characterization of enzymes of energy metabolism. Dr. Natael Maximiliano Wayllace is a Postdoctoral Researcher at the Center for Photosynthetic and Biochemical Studies (CEFOBI-CONICET), National University of Rosario, Argentina. He obtained his PhD in Biological Sciences in 2024, where he discovered and characterized novel microbial enzymes, with a particular focus on extremophilic systems, including cold-adapted and thermostable glucoamylases. His research combines biochemical and kinetic characterization with computational modeling to investigate enzyme adaptation mechanisms and structure–function relationships. Dr. Wayllace has authored several peer-reviewed publications on microbial enzymes, including studies on the structural and functional properties of cold-active glucoamylases. He has extensive university teaching experience and has supervised undergraduate students in biotechnology. His expertise in cold-adapted enzymes, enzymology, and protein engineering, is complemented by his academic contributions as reviewer and thesis examiner.

• 1. Structural and functional properties of cold-adapted enzymes.2. Structural features of cold-adapted enzymes3. Stability of proteins in cold environments4. Molecular mechanisms of cold-adapted enzymes5. Enzyme evolution in cold environments6. Diversity of cold-adapted enzymes7. Molecular adaptations of psychrophilic enzymes8. Bacterial cold-adapted enzymes9. Cold-adapted enzymes from Marine bacterium10. Cold-adapted enzymes in carbohydrate metabolism11. Cold-adapted proteases12. Cold-adapted metalloproteases13. Cold-adapted enzymes in lipid metabolism14. Cold-adapted amylases15. Cold-adapted redox enzymes16. Cold-adapted dehydrogenases17. Cold-adapted enzymes from Antarctic organisms18. Biotechnological applications of cold-adapted enzymes19. Recombinant expression of cold-adapted enzymes20. Protein engineering of cold-adapted enzymes21. Computational approaches to study the cold adaptation of enzymes22. Computational engineering of cold-adapted enzymes23. Biodiversity of physcrophilic bacteria24. New cold-adapted enzymes and their applications