PEGylated Nanocarriers: Applications in Drug Delivery explores the essential properties of PEG that contribute to the creation of long circulating nanocarriers while also examining the significant biological and pharmacological impacts of PEGylation and extended circulation. The book provides a detailed review of the preparation, properties, and applications of various long-circulating PEGylated nanocarriers, such as liposomes, nanoparticles, dendrimers, carbon nanotubes, and more. Key chapters also include analysis of the challenges, biological toxicity, and safety issues associated with PEGylated nanocarriers, enabling better clinical translation.
This book will be of interest to researchers and academics in the fields of biomaterials, pharmaceutical science, and polymer science who have an interest in developing PEGylated drug delivery systems for therapeutics.
- Explores PEGylated liposomes, nanoparticles, dendrimers, and nanotubes, detailing their synthesis, properties, and drug delivery applications
- Covers pharmacokinetics, toxicity, immunogenicity, and regulatory challenges for safe and effective PEGylated drug delivery systems
- Highlights PEGylated nanocarriers’ role in improving solubility, controlled drug release, in vaccines, and in gene delivery