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      1. Naturvetenskap och teknik
      2. Matematik och naturvetenskap
      3. Biologi
      4. Biokemi

      Enzymes

      Biomarkers, Targets and Therapy

      AvPriyanka Bajaj,Anatampillai Rangraj Satvik Iyenga

      Häftad, Engelska, 2027

      Del i serien Foundations and Frontiers in Enzymology

      1 826 kr

      Kommande

      Beskrivning

      Enzymes: Biomarkers, Targets and Therapy examines the critical role of enzymes in drug discovery, diagnostics, and therapeutic applications, providing essential insights for clinicians, biomedical researchers, and pharmaceutical industry professionals. This book highlights the utility of enzymes as biomarkers for disease diagnosis, targets for innovative drug discovery, and therapeutic agents in treating various conditions. Within its comprehensive chapters, the book discusses enzymatic biomarkers in neurodegenerative disorders such as Alzheimer's disease and ?-synucleinopathies, where enzymes are pivotal in understanding disease mechanisms and potential interventions.

      It covers enzymatic drug targets in cancers and diabetes, offering insights into harnessing enzymes for novel therapeutic strategies. Additionally, the book explores the role of enzymes in lipid and hypertensive disorders, emphasizing their potential in managing these conditions. Further, the book examines enzymes as therapeutic agents in autoimmune and infectious diseases, featuring approaches like CRISPR-Cas9 gene editing to tackle antimicrobial resistance. By providing curated information, this book equips its audience with the necessary knowledge to explore new directions in drug discovery and enzymatic therapy.

      • Explains the role of enzymes as biomarkers in disease diagnosis, providing clinicians with essential insights for improved diagnostic strategies
      • Discusses enzymes as targets for drug discovery, offering biomedical researchers valuable information for advancing therapeutic development
      • Evaluates the use of enzymes as therapeutic molecules, guiding pharmaceutical industry researchers in developing enzyme-based treatments

      Produktinformation

      • Utgivningsdatum:2027-10-01
      • Mått:191 x 235 x undefined mm
      • Vikt:450 g
      • Format:Häftad
      • Språk:Engelska
      • Serie:Foundations and Frontiers in Enzymology
      • Antal sidor:300
      • Förlag:Elsevier Science
      • ISBN:9780443448256

      Utforska kategorier

      • Biokemi inom Naturvetenskap och teknik
      • Biologi inom Naturvetenskap och teknik

      Mer om författaren

      Dr. Priyanka Bajaj, PhD, Editor is an Assistant Professor at the Department of Chemical Sciences at the National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India. Her group is working on the cutting-edge field of Biopharmaceutical Proteins and Enzymes. The group explores industrially important biopharmaceutical proteins like antibodies, antibody-drug conjugates (ADCs), and enzymes, including P450s, Ketoreductases, Transaminases, and others. She has 15 years of experience from her two post-doctorates at the University of Rochester, New York, and the University of Michigan, Ann Arbor, MI, USA, as well as in her PhD from NIPER, Mohali. She is the author and co-author of multiple reputed international research articles in reputed journals like Angewandte Chemie, Journal of Organic Chemistry, Biochemie and others and patents and has been awarded several national and international academic awards. She has supervised 15 master students by now and is currently supervising 08 masters and 06 PhD students. Dr. A. R. Satvik Iyengar, PhD, holds a Doctor of Philosophy degree in Medical Biochemistry from The University of Newcastle in Australia. Subsequent to his PhD he worked as a Scientific Writer in Cactus Communications in India. Prior to his PhD he graduated with a Masters in Science in Pharmaceutical Sciences from NIPER, S.A.S. Nagar in India and later worked as Junior Research fellow (JRF) at NIPER, S.A.S. Nagar. During his PhD he worked on understanding the effects of inflammation in Parkinson’s disease and during his MS and JRF tenure he has worked on Enzyme expression, purification and stabilization. He has been involved in writing scientific articles for more than a decade and has published several review and research articles. During his stint as a scientific writer for Cactus Communications he was also involved in writing medical information documents for various pharmaceutical companies that were aimed at informing health care professionals.

      Innehållsförteckning

      • 1. Introduction - Enzymes: Biomarkers, Targets and Therapy2. Enzymes in α-synucleinopathies: Biomarkers, Targets and Therapeutic molecules3. Enzymes as Biomarkers, Targets and Therapeutic molecules in Alzheimer’s disease4. Enzymes of relevance as biomarkers in cancers5. Enzymatic targets for drug discovery in cancers6. Enzymes as drug targets in diabetes7. Enzymes in lipid disorders8. Enzymes in Hypertensive disorders9. Enzymatic biomarkers in Cardiovascular Disorders10. Enzymes as biomarkers and therapeutic targets in Autoimmune Disorders11. Enzymes for treatment of bacterial diseases12. Mitigating the antimicrobial resistance through enzymes: The role of CRISPR-Cas9 gene editing
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