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    1. Medicin
    2. Medicin: allmänt

    Nanocarriers in Neurodegenerative Disorders

    Therapeutic Hopes and Hypes

    AvWael Mohamed

    Inbunden, Engelska, 2024

    2 724 kr

    Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

    Beskrivning

    Due to the lack of secure, efficient, and patient-friendly therapies for neurodegenerative disorders, there is a rising demand for innovative approaches. Despite the limited number of nanocarriers approved for human use, they have demonstrated significant potential in preclinical and, in some instances, clinical trials. In alignment with this objective, the chapters of the book are structured to offer a comprehensive overview of recent advancements in medication and dosage form development, specifically emphasizing the nanoparticulate system for targeting the brain. This book aims to furnish readers with a thorough understanding of the clinical application of nanocarrier systems for treating neurodegenerative disorders, encompassing the latest developments, challenges, safety concerns, toxicity issues, regulatory considerations, prospects, and limitations. Individuals in academia, the scientific community, business, and education seeking a more effective approach to target the brain will find valuable insights in this resource.Key FeaturesProvides a comparative perspective of various nanocarrier systems, therefore facilitating the researcher's selection of appropriate nanoparticulate carriersHighlights the related restrictions of brain delivery and current available medicinesIncludes information on the advantages and disadvantages of various biomaterials utilized in the development of nanocarriers for brain targetingEmphasizes distinct facets of surface functionalization according to the brain area of interestPresents the current advances, preclinical and clinical development, and the future potential of multiple brain-targeting technologies

    Produktinformation

    • Utgivningsdatum:2024-09-30
    • Mått:210 x 280 x undefined mm
    • Vikt:1 280 g
    • Format:Inbunden
    • Språk:Engelska
    • Antal sidor:348
    • Förlag:Taylor & Francis Ltd
    • ISBN:9781032467955

    Utforska kategorier

    • Medicin: allmänt inom Medicin
    • Biovetenskap inom Naturvetenskap och teknik
    • Maskinteknik och material inom Naturvetenskap och teknik

    Mer om författaren

    Dr. Wael Mohamed Yousef Mohamed, a Physician Neuroscientist, earned his PhD from PSU in the USA and currently holds the position of Associate Professor at IIUM Medical School in Malaysia. With an extensive background, Dr. Mohamed has been invited to deliver over 150 lectures both domestically and internationally. His contributions to Neuroscience/Psychiatry are notable, with the publication of more than 100 peer-reviewed papers, boasting an h-index of 20. Furthermore, Dr. Mohamed serves as an editor for Frontiers in Neurology and PLOS-ONE Journals, where he has contributed to various journal special issues on brain disorders. In the realm of book editing, he is actively involved with Springer, CRC, and Cambridge in the field of neuroscience. His research endeavors have attracted numerous grants from esteemed national and international organizations, including IBRO, ISN, MJF, STDF, FRGS, and INDO-ASEAN, amounting to a total research funding of half a million US$. Notably, he is the founder and chair of the AfrAbia-PD-Genomic Consortium.

    Innehållsförteckning

    • SECTION-I: NANOMEDICINE IN NEURODEGENERATIVE DISORDERSCh1 - Fundamentals of Brain–Barrier Anatomy and Global FunctionsYasser Mecheri, Soundous Malak BehloulCh2 - Blood Brain Barrier in Neurodegenrative DisordersAdejoke Elizabeth Memudu, Michael Oluwatosin GabrielCh3 - Neurodegenerative Disorders, available therapies, and their limitationsMohamed Zaki , Eman E. Mohamed , Osama M. AhmedCh4 - Challenges in brain targeting and mechanism of drug transfer across BBBAhmad Kodous, Priya Ramanathan, Arunagiri Kuha Deva Magendhra Rao, Gamal Abdel Nasser AtiaCh5 - Introduction to Nanomedicine, Nanotechnology and NanopharmaceuticalsAbdullah M. M. Elbadry, Hend H. MohamedCh6 - Regulations and Ethics of Nanomedicine and Public acceptanceNada Abdel-MonaemCh7 - Safety of Nanoparticles in MedicineMona Mohammed Abd elHakeem khalifaCh8 - Enhancing Brain Drug Delivery with Lipid Nanocarriers for Bioactive CompoundsShivakumar M Methri, Sivakumar Manickam, V. Ravichandiran, Subramanian NatesanCh9 - Blood brain Barrier disruption and Nanomedicine in Neurodegenerative disordersAdejoke Elizabeth Memudu, Michael Oluwatosin Gabriel, Grace Temitope Akingbade, Happiness Ochi Inyang, Omamuyovwi Meashack IjomoneCh10 - Worldwide Development and Commercialization of NanomedicineHadeer N. Atalah, Esraa M. QansuwaSECTION-II: NANOPARTICLES AND NEURODEGENERATIVE DISORDERSCh11 - Introduction to nanoparticles as a potential carrier for brain targeting in Neurodegenerative DisordersAdejoke Elizabeth Memudu, Michael Oluwatosin Gabriel, Victor Ebube Anadu, Olayemi Kafilat Ijomone, Omamuyovwi Meashack IjomoneCh12 - Application of polymeric nanoparticles in brain targetingMoshera SamyCh13 - Lipid-based Nanocarriers for Brain Delivery of Bio-actives in the Treatment of Neurodegenerative DisordersKhaled M. Kotb, Mohamed N. Sharafeldin, Hamsa Hassan, Achouak BOUTALBI, Ahmed Yahya, Haseen Fatima Niazi, Nouran A. Taha, Islam Omar, Amgad E. SalemCh14 - Autophagy and extracellular nanovesicles communication and their therapeutic application in neurodegenerative diseases.Mohamed Abdelkader, Noha AboQuellaCh15 - Mesoporous silica nanoparticles as promising carriers for brain deliverySudarshan Naidu Chilamakuri, Sivakumar Manickam, Rajukumar Malayandi Ravichandiran Velayutham, Subramanian NatesanCh16 - Potential of dendrimers as a nanocarrier for brain drug deliveryArab Iram Saba Gaus Mohammed, Victor Hmingthansanga, Sivakumar Manickam, V. Ravichandiran, Subramanian NatesanCh17 - Surface active ligands for brain targetingMariam Zewail, Heba Abd-El-AzimCh18 - Nanocarriers for brain delivery: Safety, Stability concerns, and regulatory aspectsAsmaa Ashraf, Mohamed Dahab, Rahma SolimanCh19 - Advancements of nanocarriers for brain targeting and limitations in clinical translationNermeen Z. Abuelezz, Fayza Eid Nasr, María-Salud García-Ayllón, Javier Sáez-Valero Ch20 - Toward Applicability of Exosomal-ncRNA Precision vs Nanoparticles to the BrainNadia M. Hamdy, Emad B. Basalious, Mona G. El-Sisi, Rana A. Youness, Ahmed S. SultanCh21 - Current advancements of nanocarriers for neurodegenerative disorders linked to toxoplasmosisMohamed Y. Zaky, Nahed S. LamloumCh22 - Toward Nano-drugs Precision for Neurodegenerative disease(s) or GliomaNadia M. Hamdy, Emad B. Basalious, Al-Aliaa Sallam, Fatma H. Shaker, Sujay Paul, Shih-Min Hsia, Mai M. Anwar