Prof Charles Oluwaseun Adetunji Prof Charles Oluwaseun Adetunji is presently a faculty member at the Microbiology Department, Faculty of Science, Edo State University Uzairue, Edo State, Nigeria, where he utilized the application of biological techniques and microbial bioprocesses for the actualization of sustainable development goals and agrarian revolution, through quality teaching, research, and community development. He was formally the Acting Director of Intellectual Property and Technology Transfer, the Head of the Department of Microbiology, Sub Dean of the Faculty of Science, and currently the Chairman Grant Committee and immediate Dean of Faculty of Science, and now the Director of Research and Innovation at EDSU.Dr. Shakira GhazanfarDr. Shakira Ghazanfar is working as Senior Scientific Officer at PARC, Islamabad, Pakistan since 2007. She did her Ph.D in Microbiology from Quaid-i-Azam University Islamabad Pakistan. Her area of research is development and commercialization of the TARGET BASED Probiotic Products based on AI/DL/ML. She is regarded among the pioneers, who have initiated Animal Probiotic Research to improve livestock productivity in Pakistan. She is the Main Organizer (100 plus training organizer) of the Training/Workshops/Webinars in her Department. Published more than 100+ research papers (400 plus impact factor), 50+ book chapters, and Main editor of CRC press USA and Springer Nature publishers' books. She is Guest Editor in well-known Journals. She co/supervised/supervising research of 20+ PhD, 100+ MPhil/BS students. She has published widely in the field of AI/ML/DL and food microbiology, drug discovery, nutraceuticals and functional foods with specialization in probiotics-based food/feed and probiotic related anticancer agents.Alessandro Di CerboProfessor Alessandro Di Cerbo, BSc, MSc, PhD, PD, is an Associate Professor of Veterinary Pharmacology and Toxicology at the University of Camerino, Italy, School of Biosciences and Veterinary Science. He has published 133 peer-reviewed papers (h-index: Google Scholar 30, Scopus 27) with 2,789 Google Scholar and 2,088 Scopus citations, edited one monograph, and authored four book chapters. Eligible to serve as a Full Professor since January 2022 and an Associate Professor since November 2020 (Italian Ministry of Education, University, and Research), he is an editorial board member or Associate Editor for several prominent journals, including Frontiers in Veterinary Science and BMC Veterinary Research. His research interests focus on pharmacological residues in animal-derived foods, animal well-being, nutraceutical efficacy, toxicological evaluations, antimicrobial activity of natural products, and nanotechnology applications in food and drugs.Ghulam Muhammad AliDr. Ghulam Muhammad Ali, Chairman of the Pakistan Agricultural Research Council (PARC), is a distinguished scientist in molecular biology and biotechnology with a PhD from the University of Liverpool and postdoctoral fellowships from Canada and Japan. He has held pivotal roles at PARC, including Director General of NARC and Member of Plant Sciences Division. Dr. Ali has published around 400 papers, led numerous research projects, and established the National Institute for Genomics and Advanced Biotechnology (NIGAB). He pioneered innovations like aeroponic potato seed production, virus-free banana varieties, and Green Super Rice development. Recognized with multiple awards, Dr. Ali’s groundbreaking work in crop improvement and food security underscores his impactful career.Wajya AjmalWajya Ajmal is an accomplished bioinformatics professional, who serves as a Scientific Officer at the National Institute for Genomics and Advanced Biotechnology (NIGAB), Islamabad, Pakistan, a role held since April 2022. With over eight years of experience in the biotechnology industry, including prior work as an Assistant Scientific Officer at NIGAB, she possess expertise in sequence analysis, bioinformatics, Python, systems biology, and Perl. A strong research background supports their work, including a Master of Philosophy (MPhil) in Bioinformatics from Quaid-i-Azam University (2012–2014) and a Bachelor of Science (BS) in Bioinformatics from COMSATS University Islamabad (2007–2011). Wajya’s career reflects a robust commitment to advancing genomics and biotechnology through innovative research and technical proficiency.Muhammad Naeem RiazNaeem Riaz is the Head of the National Institute for Genomics and Advanced Biotechnology (NIGAB) at the Pakistan Agricultural Research Council (PARC), Islamabad. A seasoned expert in molecular biology, biotechnology, and genomics, he has made significant contributions to agricultural research and innovation. With extensive experience in genomics, bioinformatics, and molecular techniques, Naeem has led pioneering research projects and spearheaded the development of advanced biotechnological solutions to enhance crop productivity and food security. Under his leadership, NIGAB has emerged as a leading biotech center, fostering innovation and training skilled researchers. Naeem Riaz's dedication to advancing biotechnology continues to drive impactful contributions to Pakistan's agricultural sector.

• Contents1. Probiotics: Introduction, Brief History and Benefits2. Chemical Characterization of Active Compounds Derived from Probiotic Microorganisms3. Relevant Patents, Social Economic Aspects and Market Share and Process Involved in the Commercialisation and Industrialization of Probiotics4. The Protective Potential Role of Probiotics against Stress Risks in Livestock5. Indigenous Developed Probiotic Products: A Promising Approach to Improve Health and Production6. Probiotic: Mode of Action and its Application in Small Ruminants7. Target-Based Probiotic: Linking the Gut Microbiota with Health and Disease8. Probiotic Cultures in Functional Dairy Products9. Probiotic Potential of Mangifera indica for the Alleviation of Lactose Intolerance10.The Identification and Application of High Potential Probiotics in the Age of Next Generation Sequencing (NGS)11.The Roles of the Human Microbiome in the Gastrointestinal Tract in Relation to Probiotics in the Management of Gastric Cancer and Other Related Diseases12.Recent Advances in the Application of Machine Learning in Development of Probiotics13.Gut-Brain Axis and Role of Probiotics14.Techniques Involved in the Isolation of Microbiome in the Gut as a Potential Probiotics15.Psychobiotics: A Microbe-Mediated Biotherapeutic for Mental Health16.Role of Probiotics to Control the Gut-Related Diseases in Terrestrial and Aquatic Animals17.The Role of Translational Research in the Development of Products Using Probiotics for Wealth Creation18.Relevant Information on Consumer’s Perspective and Diverse Sensory Evaluation of Numerous Dairy Products Using Probiotics19.Comparative Use of Bacteriotherapy in Human and Animal Gut Health

Prof Charles Oluwaseun Adetunji Prof Charles Oluwaseun Adetunji is presently a faculty member at the Microbiology Department, Faculty of Science, Edo State University Uzairue, Edo State, Nigeria, where he utilized the application of biological techniques and microbial bioprocesses for the actualization of sustainable development goals and agrarian revolution, through quality teaching, research, and community development. He was formally the Acting Director of Intellectual Property and Technology Transfer, the Head of the Department of Microbiology, Sub Dean of the Faculty of Science, and currently the Chairman Grant Committee and immediate Dean of Faculty of Science, and now the Director of Research and Innovation at EDSU.Dr. Shakira GhazanfarDr. Shakira Ghazanfar is working as Senior Scientific Officer at PARC, Islamabad, Pakistan since 2007. She did her Ph.D in Microbiology from Quaid-i-Azam University Islamabad Pakistan. Her area of research is development and commercialization of the TARGET BASED Probiotic Products based on AI/DL/ML. She is regarded among the pioneers, who have initiated Animal Probiotic Research to improve livestock productivity in Pakistan. She is the Main Organizer (100 plus training organizer) of the Training/Workshops/Webinars in her Department. Published more than 100+ research papers (400 plus impact factor), 50+ book chapters, and Main editor of CRC press USA and Springer Nature publishers' books. She is Guest Editor in well-known Journals. She co/supervised/supervising research of 20+ PhD, 100+ MPhil/BS students. She has published widely in the field of AI/ML/DL and food microbiology, drug discovery, nutraceuticals and functional foods with specialization in probiotics-based food/feed and probiotic related anticancer agents.Alessandro Di CerboProfessor Alessandro Di Cerbo, BSc, MSc, PhD, PD, is an Associate Professor of Veterinary Pharmacology and Toxicology at the University of Camerino, Italy, School of Biosciences and Veterinary Science. He has published 133 peer-reviewed papers (h-index: Google Scholar 30, Scopus 27) with 2,789 Google Scholar and 2,088 Scopus citations, edited one monograph, and authored four book chapters. Eligible to serve as a Full Professor since January 2022 and an Associate Professor since November 2020 (Italian Ministry of Education, University, and Research), he is an editorial board member or Associate Editor for several prominent journals, including Frontiers in Veterinary Science and BMC Veterinary Research. His research interests focus on pharmacological residues in animal-derived foods, animal well-being, nutraceutical efficacy, toxicological evaluations, antimicrobial activity of natural products, and nanotechnology applications in food and drugs.Ghulam Muhammad AliDr. Ghulam Muhammad Ali, Chairman of the Pakistan Agricultural Research Council (PARC), is a distinguished scientist in molecular biology and biotechnology with a PhD from the University of Liverpool and postdoctoral fellowships from Canada and Japan. He has held pivotal roles at PARC, including Director General of NARC and Member of Plant Sciences Division. Dr. Ali has published around 400 papers, led numerous research projects, and established the National Institute for Genomics and Advanced Biotechnology (NIGAB). He pioneered innovations like aeroponic potato seed production, virus-free banana varieties, and Green Super Rice development. Recognized with multiple awards, Dr. Ali’s groundbreaking work in crop improvement and food security underscores his impactful career.Wajya AjmalWajya Ajmal is an accomplished bioinformatics professional, who serves as a Scientific Officer at the National Institute for Genomics and Advanced Biotechnology (NIGAB), Islamabad, Pakistan, a role held since April 2022. With over eight years of experience in the biotechnology industry, including prior work as an Assistant Scientific Officer at NIGAB, she possess expertise in sequence analysis, bioinformatics, Python, systems biology, and Perl. A strong research background supports their work, including a Master of Philosophy (MPhil) in Bioinformatics from Quaid-i-Azam University (2012–2014) and a Bachelor of Science (BS) in Bioinformatics from COMSATS University Islamabad (2007–2011). Wajya’s career reflects a robust commitment to advancing genomics and biotechnology through innovative research and technical proficiency.Muhammad Naeem RiazNaeem Riaz is the Head of the National Institute for Genomics and Advanced Biotechnology (NIGAB) at the Pakistan Agricultural Research Council (PARC), Islamabad. A seasoned expert in molecular biology, biotechnology, and genomics, he has made significant contributions to agricultural research and innovation. With extensive experience in genomics, bioinformatics, and molecular techniques, Naeem has led pioneering research projects and spearheaded the development of advanced biotechnological solutions to enhance crop productivity and food security. Under his leadership, NIGAB has emerged as a leading biotech center, fostering innovation and training skilled researchers. Naeem Riaz's dedication to advancing biotechnology continues to drive impactful contributions to Pakistan's agricultural sector.

• Contents1. Probiotics: Introduction, Brief History and Benefits2. Chemical Characterization of Active Compounds Derived from Probiotic Microorganisms3. Relevant Patents, Social Economic Aspects and Market Share and Process Involved in the Commercialisation and Industrialization of Probiotics4. The Protective Potential Role of Probiotics against Stress Risks in Livestock5. Indigenous Developed Probiotic Products: A Promising Approach to Improve Health and Production6. Probiotic: Mode of Action and its Application in Small Ruminants7. Target-Based Probiotic: Linking the Gut Microbiota with Health and Disease8. Probiotic Cultures in Functional Dairy Products9. Probiotic Potential of Mangifera indica for the Alleviation of Lactose Intolerance10.The Identification and Application of High Potential Probiotics in the Age of Next Generation Sequencing (NGS)11.The Roles of the Human Microbiome in the Gastrointestinal Tract in Relation to Probiotics in the Management of Gastric Cancer and Other Related Diseases12.Recent Advances in the Application of Machine Learning in Development of Probiotics13.Gut-Brain Axis and Role of Probiotics14.Techniques Involved in the Isolation of Microbiome in the Gut as a Potential Probiotics15.Psychobiotics: A Microbe-Mediated Biotherapeutic for Mental Health16.Role of Probiotics to Control the Gut-Related Diseases in Terrestrial and Aquatic Animals17.The Role of Translational Research in the Development of Products Using Probiotics for Wealth Creation18.Relevant Information on Consumer’s Perspective and Diverse Sensory Evaluation of Numerous Dairy Products Using Probiotics19.Comparative Use of Bacteriotherapy in Human and Animal Gut Health

Prof Charles Oluwaseun Adetunji Prof Charles Oluwaseun Adetunji is presently a faculty member at the Microbiology Department, Faculty of Science, Edo State University Uzairue, Edo State, Nigeria, where he utilized the application of biological techniques and microbial bioprocesses for the actualization of sustainable development goals and agrarian revolution, through quality teaching, research, and community development. He was formally the Acting Director of Intellectual Property and Technology Transfer, the Head of the Department of Microbiology, Sub Dean of the Faculty of Science, and currently the Chairman Grant Committee and immediate Dean of Faculty of Science, and now the Director of Research and Innovation at EDSU.Dr. Shakira GhazanfarDr. Shakira Ghazanfar is working as Senior Scientific Officer at PARC, Islamabad, Pakistan since 2007. She did her Ph.D in Microbiology from Quaid-i-Azam University Islamabad Pakistan. Her area of research is development and commercialization of the TARGET BASED Probiotic Products based on AI/DL/ML. She is regarded among the pioneers, who have initiated Animal Probiotic Research to improve livestock productivity in Pakistan. She is the Main Organizer (100 plus training organizer) of the Training/Workshops/Webinars in her Department. Published more than 100+ research papers (400 plus impact factor), 50+ book chapters, and Main editor of CRC press USA and Springer Nature publishers' books. She is Guest Editor in well-known Journals. She co/supervised/supervising research of 20+ PhD, 100+ MPhil/BS students. She has published widely in the field of AI/ML/DL and food microbiology, drug discovery, nutraceuticals and functional foods with specialization in probiotics-based food/feed and probiotic related anticancer agents.Alessandro Di CerboProfessor Alessandro Di Cerbo, BSc, MSc, PhD, PD, is an Associate Professor of Veterinary Pharmacology and Toxicology at the University of Camerino, Italy, School of Biosciences and Veterinary Science. He has published 133 peer-reviewed papers (h-index: Google Scholar 30, Scopus 27) with 2,789 Google Scholar and 2,088 Scopus citations, edited one monograph, and authored four book chapters. Eligible to serve as a Full Professor since January 2022 and an Associate Professor since November 2020 (Italian Ministry of Education, University, and Research), he is an editorial board member or Associate Editor for several prominent journals, including Frontiers in Veterinary Science and BMC Veterinary Research. His research interests focus on pharmacological residues in animal-derived foods, animal well-being, nutraceutical efficacy, toxicological evaluations, antimicrobial activity of natural products, and nanotechnology applications in food and drugs.Ghulam Muhammad AliDr. Ghulam Muhammad Ali, Chairman of the Pakistan Agricultural Research Council (PARC), is a distinguished scientist in molecular biology and biotechnology with a PhD from the University of Liverpool and postdoctoral fellowships from Canada and Japan. He has held pivotal roles at PARC, including Director General of NARC and Member of Plant Sciences Division. Dr. Ali has published around 400 papers, led numerous research projects, and established the National Institute for Genomics and Advanced Biotechnology (NIGAB). He pioneered innovations like aeroponic potato seed production, virus-free banana varieties, and Green Super Rice development. Recognized with multiple awards, Dr. Ali’s groundbreaking work in crop improvement and food security underscores his impactful career.Wajya AjmalWajya Ajmal is an accomplished bioinformatics professional, who serves as a Scientific Officer at the National Institute for Genomics and Advanced Biotechnology (NIGAB), Islamabad, Pakistan, a role held since April 2022. With over eight years of experience in the biotechnology industry, including prior work as an Assistant Scientific Officer at NIGAB, she possess expertise in sequence analysis, bioinformatics, Python, systems biology, and Perl. A strong research background supports their work, including a Master of Philosophy (MPhil) in Bioinformatics from Quaid-i-Azam University (2012–2014) and a Bachelor of Science (BS) in Bioinformatics from COMSATS University Islamabad (2007–2011). Wajya’s career reflects a robust commitment to advancing genomics and biotechnology through innovative research and technical proficiency.Muhammad Naeem RiazNaeem Riaz is the Head of the National Institute for Genomics and Advanced Biotechnology (NIGAB) at the Pakistan Agricultural Research Council (PARC), Islamabad. A seasoned expert in molecular biology, biotechnology, and genomics, he has made significant contributions to agricultural research and innovation. With extensive experience in genomics, bioinformatics, and molecular techniques, Naeem has led pioneering research projects and spearheaded the development of advanced biotechnological solutions to enhance crop productivity and food security. Under his leadership, NIGAB has emerged as a leading biotech center, fostering innovation and training skilled researchers. Naeem Riaz's dedication to advancing biotechnology continues to drive impactful contributions to Pakistan's agricultural sector.

• Contents1. Probiotics: Introduction, Brief History and Benefits2. Chemical Characterization of Active Compounds Derived from Probiotic Microorganisms3. Relevant Patents, Social Economic Aspects and Market Share and Process Involved in the Commercialisation and Industrialization of Probiotics4. The Protective Potential Role of Probiotics against Stress Risks in Livestock5. Indigenous Developed Probiotic Products: A Promising Approach to Improve Health and Production6. Probiotic: Mode of Action and its Application in Small Ruminants7. Target-Based Probiotic: Linking the Gut Microbiota with Health and Disease8. Probiotic Cultures in Functional Dairy Products9. Probiotic Potential of Mangifera indica for the Alleviation of Lactose Intolerance10.The Identification and Application of High Potential Probiotics in the Age of Next Generation Sequencing (NGS)11.The Roles of the Human Microbiome in the Gastrointestinal Tract in Relation to Probiotics in the Management of Gastric Cancer and Other Related Diseases12.Recent Advances in the Application of Machine Learning in Development of Probiotics13.Gut-Brain Axis and Role of Probiotics14.Techniques Involved in the Isolation of Microbiome in the Gut as a Potential Probiotics15.Psychobiotics: A Microbe-Mediated Biotherapeutic for Mental Health16.Role of Probiotics to Control the Gut-Related Diseases in Terrestrial and Aquatic Animals17.The Role of Translational Research in the Development of Products Using Probiotics for Wealth Creation18.Relevant Information on Consumer’s Perspective and Diverse Sensory Evaluation of Numerous Dairy Products Using Probiotics19.Comparative Use of Bacteriotherapy in Human and Animal Gut Health