Edited by Slavo Radosevic, Professor of Industry and Innovation Studies, School of Slavonic and East European Studies, University College London, UK, Sylvia Schwaag Serger, Professor of Research Policy, Department of Economic History, Lund University, Sweden and Luc Soete, Emeritus Professor of Economics, UNU-MERIT, School of Business and Economics, Maastricht University, the Netherlands

‘An outstanding and much-needed Handbook that convincingly demonstrates why regions are truly critical arenas for transformative innovation policy. Its global perspective, conceptual depth, and empirical richness make it essential reading for scholars, policymakers, and practitioners seeking to understand and advance innovation, sustainability transitions, and place-based development strategies.’

• ContentsPART I INTRODUCTION AND OVERVIEW1 Why a handbook on regions and transformative innovation policy? 2Sylvia Schwaag Serger and Luc Soete2 Introducing the chapters: an overview 9Slavo RadosevicPART II CONCEPTUAL CHALLENGES OF REGIONAL TRANSFORMATIVEINNOVATION POLICY3 Enhancing the sustainability dimension in smart specialisation strategies:towards a framework for reflexive policy practice 29Michał Miedziński, Lars Coenen and Henrik Larsen4 Exploring the governance challenge of regional transformative innovationpolicies: a metagovernance perspective 53Ainhoa Arrona and Edurne Magro5 Transforming regions, change agency, and policy 69Markus Grillitsch6 From problems to opportunities: a place-based approach to transformativeinnovation policy 87Elvira UyarraPART III REGIONS IN THE TRANSFORMATION TO SUSTAINABILITY7 From smart specialisation to smart transformation – (how) do regionsintegrate transformative intentions in regional innovation priorities? 103Sofia Avdeitchikova- and Anders Olsson8 Embedding sustainability transitions in Catalonia’s smart specialisationstrategy 120Tatiana Fernández Sirera and Michał Miedziński9 Conditions for sustainability transitions in Germany’s peripheral regions: adifferentiated view on regional change agency 137Henning Kroll, Max Roessler, Valeria Maruseva and Daniel Schiller10 Sustainable foodscapes: the transformation of public food systems 155Kevin Morgan11 Unravelling innovation transition traps: the imperative of collective action 171Peter Wostner, Anže Burger, Iztok Palčič and Sonja Šlander Wostner12 Contrasting pathways to regional transformative policies: bottom-upapproaches of a leading and latecomer region in Czechia 190Jiří Blažek, Viktor Květoň, Vojtěch Kadlec and Jan PojslPART IV TRANSFORMATIVE REGIONAL INNOVATION POLICY GOES GLOBAL13 Public-private partnerships and regional transformative innovation policyin the US 211Monica Novoa and Paige Clayton14 Innovation and the states: the regional manifestations of the EndlessFrontier in the US Rust Belt 229Ben Armstrong and Dan Traficonte15 Regional entrepreneurial mentoring networks as transformative innovationpolicy: insights from a semi-peripheral high tech hub 242Darius Ornston and Isabelle Watkinson16 The evolution of Korea’s regional innovation system: the case of DaedeokInnopolis 257Hye-Ran Hwang and Jae-Yong Choung17 Integrating ‘Society 5.0’ and regional revitalisation: Japan’s path totransformative innovation 278Michiko Iizuka and Takayuki Hayashi18 Latin America and transformative innovation policy 296Matias Ramirez19 The urban transformation of Medellín: confluence of innovation processesand transformation limits 309Jorge Robledo Velásquez, Walter Lugo Ruiz Castañeda and MaríaLuisa Villalba Morales20 Strengthening inclusive innovation systems: analysis of the Western Cape’seconomic development activities 328Sara Grobbelaar21 Green goals, strategic actions: China’s experience with transformativeinnovation policy 348Hannah Yi Wei22 Regional transformative innovation policy towards green development inChina 368Zhen Yu and Lan Xue23 Reorienting STI policy for transformative change: lessons from and forIndia 381Soutrik Basu24 The less-than-one percent: how a few firms shape regional capabilities inIndia 397Nanditha Mathew and Emanuele PugliesePART V CONCLUSIONS AND ISSUES FOR FURTHER RESEARCH25 Transformative regional innovation policy globally: state of the art andissues for future research 425Slavo Radosevic26 Epilogue 441Sylvia Schwaag Serger and Luc Soete

Edited by Slavo Radosevic, Professor of Industry and Innovation Studies, School of Slavonic and East European Studies, University College London, UK, Sylvia Schwaag Serger, Professor of Research Policy, Department of Economic History, Lund University, Sweden and Luc Soete, Emeritus Professor of Economics, UNU-MERIT, School of Business and Economics, Maastricht University, the Netherlands

‘An outstanding and much-needed Handbook that convincingly demonstrates why regions are truly critical arenas for transformative innovation policy. Its global perspective, conceptual depth, and empirical richness make it essential reading for scholars, policymakers, and practitioners seeking to understand and advance innovation, sustainability transitions, and place-based development strategies.’

• ContentsPART I INTRODUCTION AND OVERVIEW1 Why a handbook on regions and transformative innovation policy? 2Sylvia Schwaag Serger and Luc Soete2 Introducing the chapters: an overview 9Slavo RadosevicPART II CONCEPTUAL CHALLENGES OF REGIONAL TRANSFORMATIVEINNOVATION POLICY3 Enhancing the sustainability dimension in smart specialisation strategies:towards a framework for reflexive policy practice 29Michał Miedziński, Lars Coenen and Henrik Larsen4 Exploring the governance challenge of regional transformative innovationpolicies: a metagovernance perspective 53Ainhoa Arrona and Edurne Magro5 Transforming regions, change agency, and policy 69Markus Grillitsch6 From problems to opportunities: a place-based approach to transformativeinnovation policy 87Elvira UyarraPART III REGIONS IN THE TRANSFORMATION TO SUSTAINABILITY7 From smart specialisation to smart transformation – (how) do regionsintegrate transformative intentions in regional innovation priorities? 103Sofia Avdeitchikova- and Anders Olsson8 Embedding sustainability transitions in Catalonia’s smart specialisationstrategy 120Tatiana Fernández Sirera and Michał Miedziński9 Conditions for sustainability transitions in Germany’s peripheral regions: adifferentiated view on regional change agency 137Henning Kroll, Max Roessler, Valeria Maruseva and Daniel Schiller10 Sustainable foodscapes: the transformation of public food systems 155Kevin Morgan11 Unravelling innovation transition traps: the imperative of collective action 171Peter Wostner, Anže Burger, Iztok Palčič and Sonja Šlander Wostner12 Contrasting pathways to regional transformative policies: bottom-upapproaches of a leading and latecomer region in Czechia 190Jiří Blažek, Viktor Květoň, Vojtěch Kadlec and Jan PojslPART IV TRANSFORMATIVE REGIONAL INNOVATION POLICY GOES GLOBAL13 Public-private partnerships and regional transformative innovation policyin the US 211Monica Novoa and Paige Clayton14 Innovation and the states: the regional manifestations of the EndlessFrontier in the US Rust Belt 229Ben Armstrong and Dan Traficonte15 Regional entrepreneurial mentoring networks as transformative innovationpolicy: insights from a semi-peripheral high tech hub 242Darius Ornston and Isabelle Watkinson16 The evolution of Korea’s regional innovation system: the case of DaedeokInnopolis 257Hye-Ran Hwang and Jae-Yong Choung17 Integrating ‘Society 5.0’ and regional revitalisation: Japan’s path totransformative innovation 278Michiko Iizuka and Takayuki Hayashi18 Latin America and transformative innovation policy 296Matias Ramirez19 The urban transformation of Medellín: confluence of innovation processesand transformation limits 309Jorge Robledo Velásquez, Walter Lugo Ruiz Castañeda and MaríaLuisa Villalba Morales20 Strengthening inclusive innovation systems: analysis of the Western Cape’seconomic development activities 328Sara Grobbelaar21 Green goals, strategic actions: China’s experience with transformativeinnovation policy 348Hannah Yi Wei22 Regional transformative innovation policy towards green development inChina 368Zhen Yu and Lan Xue23 Reorienting STI policy for transformative change: lessons from and forIndia 381Soutrik Basu24 The less-than-one percent: how a few firms shape regional capabilities inIndia 397Nanditha Mathew and Emanuele PugliesePART V CONCLUSIONS AND ISSUES FOR FURTHER RESEARCH25 Transformative regional innovation policy globally: state of the art andissues for future research 425Slavo Radosevic26 Epilogue 441Sylvia Schwaag Serger and Luc Soete

Edited by Slavo Radosevic, Professor of Industry and Innovation Studies, School of Slavonic and East European Studies, University College London, UK, Sylvia Schwaag Serger, Professor of Research Policy, Department of Economic History, Lund University, Sweden and Luc Soete, Emeritus Professor of Economics, UNU-MERIT, School of Business and Economics, Maastricht University, the Netherlands

‘An outstanding and much-needed Handbook that convincingly demonstrates why regions are truly critical arenas for transformative innovation policy. Its global perspective, conceptual depth, and empirical richness make it essential reading for scholars, policymakers, and practitioners seeking to understand and advance innovation, sustainability transitions, and place-based development strategies.’

• ContentsPART I INTRODUCTION AND OVERVIEW1 Why a handbook on regions and transformative innovation policy? 2Sylvia Schwaag Serger and Luc Soete2 Introducing the chapters: an overview 9Slavo RadosevicPART II CONCEPTUAL CHALLENGES OF REGIONAL TRANSFORMATIVEINNOVATION POLICY3 Enhancing the sustainability dimension in smart specialisation strategies:towards a framework for reflexive policy practice 29Michał Miedziński, Lars Coenen and Henrik Larsen4 Exploring the governance challenge of regional transformative innovationpolicies: a metagovernance perspective 53Ainhoa Arrona and Edurne Magro5 Transforming regions, change agency, and policy 69Markus Grillitsch6 From problems to opportunities: a place-based approach to transformativeinnovation policy 87Elvira UyarraPART III REGIONS IN THE TRANSFORMATION TO SUSTAINABILITY7 From smart specialisation to smart transformation – (how) do regionsintegrate transformative intentions in regional innovation priorities? 103Sofia Avdeitchikova- and Anders Olsson8 Embedding sustainability transitions in Catalonia’s smart specialisationstrategy 120Tatiana Fernández Sirera and Michał Miedziński9 Conditions for sustainability transitions in Germany’s peripheral regions: adifferentiated view on regional change agency 137Henning Kroll, Max Roessler, Valeria Maruseva and Daniel Schiller10 Sustainable foodscapes: the transformation of public food systems 155Kevin Morgan11 Unravelling innovation transition traps: the imperative of collective action 171Peter Wostner, Anže Burger, Iztok Palčič and Sonja Šlander Wostner12 Contrasting pathways to regional transformative policies: bottom-upapproaches of a leading and latecomer region in Czechia 190Jiří Blažek, Viktor Květoň, Vojtěch Kadlec and Jan PojslPART IV TRANSFORMATIVE REGIONAL INNOVATION POLICY GOES GLOBAL13 Public-private partnerships and regional transformative innovation policyin the US 211Monica Novoa and Paige Clayton14 Innovation and the states: the regional manifestations of the EndlessFrontier in the US Rust Belt 229Ben Armstrong and Dan Traficonte15 Regional entrepreneurial mentoring networks as transformative innovationpolicy: insights from a semi-peripheral high tech hub 242Darius Ornston and Isabelle Watkinson16 The evolution of Korea’s regional innovation system: the case of DaedeokInnopolis 257Hye-Ran Hwang and Jae-Yong Choung17 Integrating ‘Society 5.0’ and regional revitalisation: Japan’s path totransformative innovation 278Michiko Iizuka and Takayuki Hayashi18 Latin America and transformative innovation policy 296Matias Ramirez19 The urban transformation of Medellín: confluence of innovation processesand transformation limits 309Jorge Robledo Velásquez, Walter Lugo Ruiz Castañeda and MaríaLuisa Villalba Morales20 Strengthening inclusive innovation systems: analysis of the Western Cape’seconomic development activities 328Sara Grobbelaar21 Green goals, strategic actions: China’s experience with transformativeinnovation policy 348Hannah Yi Wei22 Regional transformative innovation policy towards green development inChina 368Zhen Yu and Lan Xue23 Reorienting STI policy for transformative change: lessons from and forIndia 381Soutrik Basu24 The less-than-one percent: how a few firms shape regional capabilities inIndia 397Nanditha Mathew and Emanuele PugliesePART V CONCLUSIONS AND ISSUES FOR FURTHER RESEARCH25 Transformative regional innovation policy globally: state of the art andissues for future research 425Slavo Radosevic26 Epilogue 441Sylvia Schwaag Serger and Luc Soete