This comprehensive new two-volume work provides detailed explanations of the procedures involved in the development and manufacture of biopharmaceuticals as well as the uses and applications in healthcare and medicine.Volume 1 offers an introduction and overview of pharmaceutical technology, covering the principals and science of biotechnology. It explains genetic engineering that involves laboratory-based technologies to alter the DNA makeup of an organism; protein engineering to develop valuable proteins through the design and production of unnatural polypeptides; recombinant DNA technology to manipulate and isolate DNA segments of interest; and microbial biotransformation, which transforms absorbed nutrients (food, oxygen, etc.) into substances required for normal body functions.
