Vivek P. Chavda – författare

Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across various platforms, and the path to commercialization. This book provides an introductory overview of vaccines, covering various types, developmental methodologies, delivery systems, adjuvants, immunization, and measurement of vaccine efficacy. It also showcases examples of vaccine research efforts targeting infectious diseases, autoimmune disorders, and cancer. The book concludes by exploring cutting-edge advances in proteogenomics, immunopeptidomics, and future vaccine technologies.The primary objective of this book is to inform a broad scientific audience about the fundamental concepts underlying vaccine and immunology. Further, it serves as an invaluable reference for understanding the critical steps in the journey from discovery to regulatory processes for human clinical trials, addressing common misconceptions and presenting factual information about vaccinations. Advanced Vaccination Technologies for Infectious and Chronic Diseases is a requisite reference for occupational health professionals whose roles involve supervision of immunization programs such as those working within the National Health Service, some sectors of higher education, or the pharmaceutical industry. It also caters to those researchers engaged in vaccine development and all who want to learn the processes involved from laboratory research to final product.

SARS-CoV-2, the coronavirus responsible for COVID-19, wreaked havoc on the world; it could both spread easily and mutate rapidly, leading to the decrease in the effectiveness of newly developed vaccines over time. The detection of these mutated variants and the development of more efficient vaccines requires significant effort and increased knowledge in this field. This new book, SARS-CoV-2 Variants and Global Population Vulnerability: Diagnostic Strategies, Vaccine Development, and Therapeutic Management, provides detailed and systemic information regarding the biology and immunophysiology of SARS-CoV-2 and highlights the global vulnerability of the world population to SARS-CoV-2 infection and COVID-19.

The book covers different aspects pertaining to the SARS-CoV-2 variants and their relation to global vulnerability. Chapters discuss the diagnostics, vaccine development, and therapeutic management starting from the zoonotic origin, organization, and transmission of SARS-CoV-2, lifestyle and immunophysiology of the virus, detection and diagnosis techniques, and analytical techniques. The book also observes the global impact of Delta and Omicron SARS-CoV-2 variants. It looks at the drug repurposing and new drug discovery routines for the emerging variants. It presents strategies for fast-track vaccine development, the roles of nasal vaccines and nucleic acid vaccines for COVID-19 management, monoclonal antibody therapy for the diseases management, along with the use of dietary supplements and nutraceuticals, herbal drugs, and other alternative remedies for COVID-19 management. The book also considers the social and environmental impacts of SARS-CoV-2 variants and the current challenges, outlining aspects that can help in developing more efficacious means for controlling SARS-CoV-2 in the future.

Key highlights:

With its unique and thorough take on the subject, this book is an important resource of know-how for investigators working in this area. Professionals from the pharmaceutical industry as well as students, research scholars, doctors, and other healthcare professionals will find this book of particular value.

SARS-CoV-2, the coronavirus responsible for COVID-19, wreaked havoc on the world; it could both spread easily and mutate rapidly, leading to the decrease in the effectiveness of newly developed vaccines over time. The detection of these mutated variants and the development of more efficient vaccines requires significant effort and increased knowledge in this field. This new book, SARS-CoV-2 Variants and Global Population Vulnerability: Diagnostic Strategies, Vaccine Development, and Therapeutic Management, provides detailed and systemic information regarding the biology and immunophysiology of SARS-CoV-2 and highlights the global vulnerability of the world population to SARS-CoV-2 infection and COVID-19.

The book covers different aspects pertaining to the SARS-CoV-2 variants and their relation to global vulnerability. Chapters discuss the diagnostics, vaccine development, and therapeutic management starting from the zoonotic origin, organization, and transmission of SARS-CoV-2, lifestyle and immunophysiology of the virus, detection and diagnosis techniques, and analytical techniques. The book also observes the global impact of Delta and Omicron SARS-CoV-2 variants. It looks at the drug repurposing and new drug discovery routines for the emerging variants. It presents strategies for fast-track vaccine development, the roles of nasal vaccines and nucleic acid vaccines for COVID-19 management, monoclonal antibody therapy for the diseases management, along with the use of dietary supplements and nutraceuticals, herbal drugs, and other alternative remedies for COVID-19 management. The book also considers the social and environmental impacts of SARS-CoV-2 variants and the current challenges, outlining aspects that can help in developing more efficacious means for controlling SARS-CoV-2 in the future.

Key highlights:

With its unique and thorough take on the subject, this book is an important resource of know-how for investigators working in this area. Professionals from the pharmaceutical industry as well as students, research scholars, doctors, and other healthcare professionals will find this book of particular value.

A timely book that details bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies, for drug development in the pharmaceutical and medical sciences industries.

The book contains 17 chapters categorized into 3 sections. The first section presents the latest information on bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies. The following 2 sections include bioinformatics tools for the pharmaceutical sector and the healthcare sector. Bioinformatics brings a new era in research to accelerate drug target and vaccine design development, improving validation approaches as well as facilitating and identifying side effects and predicting drug resistance. As such, this will aid in more successful drug candidates from discovery to clinical trials to the market, and most importantly make it a more cost-effective process overall.

Readers will find in this book:

Audience

The book will be used by researchers and scientists in academia and industry including drug developers, computational biochemists, bioinformaticians, immunologists, pharmaceutical and medical sciences, as well as those in artificial intelligence and machine learning.

A timely book that details bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies, for drug development in the pharmaceutical and medical sciences industries.

The book contains 17 chapters categorized into 3 sections. The first section presents the latest information on bioinformatics tools, artificial intelligence, machine learning, computational methods, protein interactions, peptide-based drug design, and omics technologies. The following 2 sections include bioinformatics tools for the pharmaceutical sector and the healthcare sector. Bioinformatics brings a new era in research to accelerate drug target and vaccine design development, improving validation approaches as well as facilitating and identifying side effects and predicting drug resistance. As such, this will aid in more successful drug candidates from discovery to clinical trials to the market, and most importantly make it a more cost-effective process overall.

Readers will find in this book:

Audience

The book will be used by researchers and scientists in academia and industry including drug developers, computational biochemists, bioinformaticians, immunologists, pharmaceutical and medical sciences, as well as those in artificial intelligence and machine learning.

This book details the benefits, restrictions, and types of nanoparticles used in the creation of vaccines for the treatment and prevention of illnesses.

In nanomedicine and nano-delivery systems, materials in the nanoscale range are used as diagnostic instruments or to administer therapeutic compounds to particular targeted regions in a controlled manner. By delivering precise medications to specified locations and targets, nanotechnology provides several advantages in treating chronic human illnesses. The use of nanomedicine (including chemotherapeutic medicines, biological agents, immunotherapeutic agents, etc.) in the treatment of various diseases has recently seen many notable applications. This book aims to be a single source material for understanding all the current and novel advancements in the field of nanotechnology.

In this groundbreaking book the reader will find:

Audience

Researchers and pharmacy students in biomedical engineering and chemical engineering, biotechnology, as well as pharmaceutical and biopharmaceutical industry engineers working in drug discovery, chemical biology, computational chemistry, medicinal chemistry, and bioinformatics.

This book details the benefits, restrictions, and types of nanoparticles used in the creation of vaccines for the treatment and prevention of illnesses.

In nanomedicine and nano-delivery systems, materials in the nanoscale range are used as diagnostic instruments or to administer therapeutic compounds to particular targeted regions in a controlled manner. By delivering precise medications to specified locations and targets, nanotechnology provides several advantages in treating chronic human illnesses. The use of nanomedicine (including chemotherapeutic medicines, biological agents, immunotherapeutic agents, etc.) in the treatment of various diseases has recently seen many notable applications. This book aims to be a single source material for understanding all the current and novel advancements in the field of nanotechnology.

In this groundbreaking book the reader will find:

Audience

Researchers and pharmacy students in biomedical engineering and chemical engineering, biotechnology, as well as pharmaceutical and biopharmaceutical industry engineers working in drug discovery, chemical biology, computational chemistry, medicinal chemistry, and bioinformatics.

The book presents invaluable insights into the latest advancements, challenges, and research on vaccine adjuvants, which are key to developing more effective and safer vaccines essential for tackling pressing global health challenges.

Emerging Pathways of Vaccine Adjuvants: A Nonspecific Stimulant of the Immune System aims to drive progress in vaccine research, paving the way for the development of more potent and safer vaccines to address global health threats. This volume provides a comprehensive overview of the evolving landscape of vaccine adjuvants, encompassing a wide range of topics critical to their design, development, and application. Adjuvants play a crucial role in vaccine formulations by boosting the immunogenicity of antigens, thereby enhancing vaccine efficacy. While antigens can initiate immune responses independently, adjuvants amplify these responses. Extensive research efforts are focused on the formulation of adjuvants to establish accurate, efficient, and safe manufacturing techniques. This book provides a clear explanation of the strict regulatory issues, making it an essential resource for students, businesspeople, and academics across the globe.

Readers will find the book:

Audience

Researchers and pharmacy students in biomedical engineering and chemical engineering, biotechnology, as well as pharmaceutical and biopharmaceutical industry engineers working in drug discovery, chemical biology, computational chemistry, medicinal chemistry, and bioinformatics.

The book presents invaluable insights into the latest advancements, challenges, and research on vaccine adjuvants, which are key to developing more effective and safer vaccines essential for tackling pressing global health challenges.

Emerging Pathways of Vaccine Adjuvants: A Nonspecific Stimulant of the Immune System aims to drive progress in vaccine research, paving the way for the development of more potent and safer vaccines to address global health threats. This volume provides a comprehensive overview of the evolving landscape of vaccine adjuvants, encompassing a wide range of topics critical to their design, development, and application. Adjuvants play a crucial role in vaccine formulations by boosting the immunogenicity of antigens, thereby enhancing vaccine efficacy. While antigens can initiate immune responses independently, adjuvants amplify these responses. Extensive research efforts are focused on the formulation of adjuvants to establish accurate, efficient, and safe manufacturing techniques. This book provides a clear explanation of the strict regulatory issues, making it an essential resource for students, businesspeople, and academics across the globe.

Readers will find the book:

Audience

Researchers and pharmacy students in biomedical engineering and chemical engineering, biotechnology, as well as pharmaceutical and biopharmaceutical industry engineers working in drug discovery, chemical biology, computational chemistry, medicinal chemistry, and bioinformatics.