Denis Noble, CBE, FRS, is Emeritus Professor of Cardiovascular Physiology and Director of Computational Physiology at the University of Oxford. He is one of the founders of the field of systems biology and is the current President of the International Union of Physiological Sciences (IUPS).

'Among its many merits, this remarkable book deserves to become a classic text in the philosophy of science. Almost alone among philosophers of science, Noble is a practising scientist; and unusually among practising scientists, he is an accomplished philosopher. His book brings out, with unparalleled clarity, how the scientific endeavour involves not only empirical inquiry but also conceptual structure. Noble shows how, on the negative side, popular presentations of sound biological results may be vitiated by bad metaphysics, and how, on the positive side, science and philosophy may extend the boundaries of knowledge by a unified epistemology. He ends, however, with a salutary warning that there may well be a limit to the human capacity to know the answers to ultimate questions.' Sir Anthony Kenny, University of Oxford

• Preface; Acknowledgments; 1. The universe and the principle of relativity; 2. Biological scales and levels; 3. Biological networks; 4. Nature and origin of cells; 5. Blind chance and natural selection; 6. Biological relativity; 7. Dancing nucleotides: natural genetic engineering; 8. Epigenetics and a relativistic theory of evolution; 9. The relativity of epistemology: the meaning of it all; 10. Postscript; Glossary; Index.

Denis Noble, CBE, FRS, is Emeritus Professor of Cardiovascular Physiology and Director of Computational Physiology at the University of Oxford. He is one of the founders of the field of systems biology and is the current President of the International Union of Physiological Sciences (IUPS).

'Among its many merits, this remarkable book deserves to become a classic text in the philosophy of science. Almost alone among philosophers of science, Noble is a practising scientist; and unusually among practising scientists, he is an accomplished philosopher. His book brings out, with unparalleled clarity, how the scientific endeavour involves not only empirical inquiry but also conceptual structure. Noble shows how, on the negative side, popular presentations of sound biological results may be vitiated by bad metaphysics, and how, on the positive side, science and philosophy may extend the boundaries of knowledge by a unified epistemology. He ends, however, with a salutary warning that there may well be a limit to the human capacity to know the answers to ultimate questions.' Sir Anthony Kenny, University of Oxford

• Preface; Acknowledgments; 1. The universe and the principle of relativity; 2. Biological scales and levels; 3. Biological networks; 4. Nature and origin of cells; 5. Blind chance and natural selection; 6. Biological relativity; 7. Dancing nucleotides: natural genetic engineering; 8. Epigenetics and a relativistic theory of evolution; 9. The relativity of epistemology: the meaning of it all; 10. Postscript; Glossary; Index.

Denis Noble, CBE, FRS, is Emeritus Professor of Cardiovascular Physiology and Director of Computational Physiology at the University of Oxford. He is one of the founders of the field of systems biology and is the current President of the International Union of Physiological Sciences (IUPS).

'Among its many merits, this remarkable book deserves to become a classic text in the philosophy of science. Almost alone among philosophers of science, Noble is a practising scientist; and unusually among practising scientists, he is an accomplished philosopher. His book brings out, with unparalleled clarity, how the scientific endeavour involves not only empirical inquiry but also conceptual structure. Noble shows how, on the negative side, popular presentations of sound biological results may be vitiated by bad metaphysics, and how, on the positive side, science and philosophy may extend the boundaries of knowledge by a unified epistemology. He ends, however, with a salutary warning that there may well be a limit to the human capacity to know the answers to ultimate questions.' Sir Anthony Kenny, University of Oxford

• Preface; Acknowledgments; 1. The universe and the principle of relativity; 2. Biological scales and levels; 3. Biological networks; 4. Nature and origin of cells; 5. Blind chance and natural selection; 6. Biological relativity; 7. Dancing nucleotides: natural genetic engineering; 8. Epigenetics and a relativistic theory of evolution; 9. The relativity of epistemology: the meaning of it all; 10. Postscript; Glossary; Index.