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J. Charles Eldridge, James T. Stevens - Endocrine Toxicology, Inbunden

Inbunden, Engelska, 2010

Endocrine Toxicology

Av J. Charles Eldridge, James T. Stevens

Del i serien Target Organ Toxicology Series

2188 kr

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Beskrivning
With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system. It examines endocrine toxicology’s increased importance in environmental safety issues due to legislative directives established over the past ten years.Covering all principal areas of EPA concern, Endocrine Toxicology, Third Edition provides: putative endocrine disruptors and mechanisms of endocrine toxicity the history and status of the regulatory processmechanisms of toxic effects in various hormonal systemscomparisons of the endocrine responses in humans, livestock, and wildlifetesting methods in mammalian, fish, avian, and amphibian modelsvaluable insight into the approaches of various personnel in the field, including: government officials who make and oversee policy; scientists in charge of development and validation of testing methods; basic researchers who identify toxic mechanisms; and manufacturers responsible for environmentally benign product certification
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Eldridge, J. Charles; Stevens, James T.

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"This is an excellent review of the effects of toxic substances on endocrine axes in both humans and wildlife.... The ambitious goals of covering the expanse of molecular toxicology and regulatory action are met by the book's diverse chapters......Because of the array of authors, the book serves as an excellent introduction to many areas related to endocrine toxicology....... The book does an excellent job of covering the topics in endocrine disruption that have become increasingly relevant over the last three decades. The classic mechanisms of endocrine disruption, namely alterations in estrogen and androgen signaling, are covered in two excellent chapters....As a whole, this book offers an excellent review of the effects of toxins on endocrine physiology with a particular strength in its coverage of government programs for monitoring these effects and the subsequent implications for regulatory policy. Because of the burgeoning knowledge in this area, this update is certainly appreciated, and subsequent editions will be welcome as our knowledge of endocrine disruption expands to other areas of endocrine physiology."Weighted Numerical Score: 94 - 4 Stars![DOODY'S NOTES][REVIEWER'S EXPERT OPINION]Robert Michael Sargis, M.D., Ph.D.(University of Chicago Medical Center)

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