Eating Disorders and Obesity, Third Edition

Kelly D. Brownell, PhD, is Dean of the Sanford School of Public Policy at Duke University, where he is also Robert L. Flowers Professor of Public Policy and Professor of Psychology and Neuroscience. Prior to joining the faculty at Duke, Dr. Brownell was the James Rowland Angell Professor of Psychology, Professor of Epidemiology and Public Health, and Director of the Rudd Center for Food Policy and Obesity at Yale University. His work focuses on obesity and food policy. Dr. Brownell has been named to the National Academy of Medicine (Institute of Medicine); has received numerous awards, including the Lifetime Achievement Award from the American Psychological Association; and in 2006 was named by Time magazine as one of the World’s 100 Most Influential People.B. Timothy Walsh, MD, is Ruane Professor of Pediatric Psychopharmacology at the College of Physicians and Surgeons of Columbia University and Director of the Division of Clinical Therapeutics at the New York State Psychiatric Institute. The clinical research group he founded and has led at Columbia has conducted studies of the etiology and treatment of eating disorders, with a particular focus on underlying pathophysiological mechanisms. Dr. Walsh has served as president of the Academy for Eating Disorders and of the Eating Disorders Research Society, and chaired the Eating Disorders Work Group for DSM-IV and DSM-5. He has received awards from the American Psychiatric Association, the Academy for Eating Disorders, the National Eating Disorders Association, and the Association for Behavioral and Cognitive Therapies.

"Although the fields of obesity and eating disorders still sit side by side with only tentative tendrils combining them, this handbook, over subsequent editions, is helping to foster needed integration. The brief, easily read chapters in the third edition provide an up-to-date and comprehensive survey of both fields."--W. Stewart Agras, MD, Department of Psychiatry and Behavioral Sciences (Emeritus), Stanford University"This thoroughly updated handbook once again assembles a world-class roster of authors to cover the state of the science in eating and weight disorders. The third edition features important new discoveries across a broad disciplinary spectrum. Grounded in research and offering well-selected recommendations for follow-up reading, this is a valuable text for courses in eating disorders, obesity, and behavioral health (to name a few). Written in clear and compelling prose, the book is a 'must read' for anyone who wants to understand and find practical solutions to the challenges and suffering that arise from eating and weight disorders.”--Ruth Striegel Weissman, PhD, Walter A. Crowell University Professor of the Social Sciences, Wesleyan University"An exceptionally well-crafted work. The fields addressed are covered broadly and deeply, yet surprisingly succinctly--a remarkable amount of material is packed into these pages. The third edition has been updated and expanded considerably, and covers developing areas of growing importance, as well as clinical and research questions that are often overlooked. The authors are the leaders in their disciplines, often the primary contributors in each field. This handbook will remain a central text for many years; I highly recommend it for practitioners, researchers, and students in various clinical and basic science fields."--James E. Mitchell, MD, The Lee A. Christoferson Chair in Neuroscience Research and Chester Fritz Distinguished University Professor, University of North Dakota School of Medicine and Health Sciences"This authoritative work examines multiple rapidly evolving facets of a highly complex area. The volume takes a 'deep dive' into the concepts and latest developments pertaining to understanding and treatment of eating disorders and obesity, including advances across medical disciplines and the behavioral sciences. It is a 'must have' for students and clinicians."--Louis J. Aronne, MD, FACP, DABOM, Sanford I. Weill Professor of Metabolic Research, Weill Cornell College of Medicine; Chairman, American Board of Obesity Medicine -

• □<□D□I□V□>□I□.□ □F□o□u□n□d□a□t□i□o□n□s□<□B□R□ □/□>□ □R□e□g□u□l□a□t□i□o□n□ □o□f□ □B□o□d□y□ □W□e□i□g□h□t□<□B□R□ □/□>□ □1□.□ □C□e□n□t□r□a□l□ □N□e□u□r□a□l□ □P□a□t□h□w□a□y□s□ □a□n□d□ □I□n□t□e□g□r□a□t□i□o□n□ □i□n□ □t□h□e□ □C□o□n□t□r□o□l□ □o□f□ □F□o□o□d□ □I□n□t□a□k□e□ □a□n□d□ □E□n□e□r□g□y□ □B□a□l□a□n□c□e□,□ □G□a□r□y□ □J□.□ □S□c□h□w□a□r□t□z□<□B□R□ □/□>□ □2□.□ □D□e□c□r□e□a□s□e□d□ □P□e□r□i□p□h□e□r□a□l□ □H□o□r□m□o□n□a□l□ □N□e□g□a□t□i□v□e□-□F□e□e□d□b□a□c□k□ □C□o□n□t□r□o□l□ □o□f□ □F□o□o□d□ □I□n□t□a□k□e□ □a□n□d□ □B□o□d□y□ □W□e□i□g□h□t□ □i□n□ □O□b□e□s□i□t□y□,□ □G□e□r□a□r□d□ □P□.□ □S□m□i□t□h□<□B□R□ □/□>□ □3□.□ □L□e□p□t□i□n□ □a□n□d□ □B□o□d□y□ □W□e□i□g□h□t□,□ □Y□i□y□i□n□g□ □Z□h□a□n□g□ □&□a□m□p□;□ □R□u□d□o□l□p□h□ □L□.□ □L□e□i□b□e□l□<□B□R□ □/□>□ □4□.□ □G□e□n□e□t□i□c□s□ □o□f□ □O□b□e□s□i□t□y□ □a□n□d□ □R□e□l□a□t□e□d□ □T□r□a□i□t□s□,□ □R□u□t□h□ □J□.□ □F□.□ □L□o□o□s□ □&□a□m□p□;□ □R□u□d□o□l□p□h□ □L□.□ □L□e□i□b□e□l□<□B□R□ □/□>□ □5□.□ □T□h□e□ □E□p□i□g□e□n□e□t□i□c□s□ □o□f□ □O□b□e□s□i□t□y□,□ □A□l□e□x□i□s□ □C□.□ □F□r□a□z□i□e□r□-□W□o□o□d□ □&□a□m□p□;□ □D□a□v□i□d□ □B□.□ □A□l□l□i□s□o□n□<□B□R□ □/□>□ □6□.□ □P□r□e□n□a□t□a□l□ □E□f□f□e□c□t□s□ □o□n□ □B□o□d□y□ □W□e□i□g□h□t□,□ □E□m□i□l□y□ □O□k□e□n□<□B□R□ □/□>□ □7□.□ □T□a□s□t□e□,□ □E□a□t□i□n□g□,□ □a□n□d□ □B□o□d□y□ □W□e□i□g□h□t□,□ □L□i□n□d□a□ □M□.□ □B□a□r□t□o□s□h□u□k□<□B□R□ □/□>□ □8□.□ □P□h□y□s□i□o□l□o□g□i□c□a□l□ □A□d□a□p□t□a□t□i□o□n□s□ □F□o□l□l□o□w□i□n□g□ □W□e□i□g□h□t□ □R□e□d□u□c□t□i□o□n□,□ □M□i□c□h□a□e□l□ □R□o□s□e□n□b□a□u□m□ □&□a□m□p□;□ □R□u□d□o□l□p□h□ □L□.□ □L□e□i□b□e□l□<□B□R□ □/□>□ □9□.□ □B□o□d□y□ □C□o□m□p□o□s□i□t□i□o□n□,□ □N□e□r□y□s□ □A□s□t□b□u□r□y□ □&□a□m□p□;□ □D□y□m□p□n□a□ □G□a□l□l□a□g□h□e□r□<□B□R□ □/□>□ □1□0□.□ □E□n□e□r□g□y□ □E□x□p□e□n□d□i□t□u□r□e□ □a□n□d□ □t□h□e□ □R□e□g□u□l□a□t□i□o□n□ □o□f□ □E□n□e□r□g□y□ □B□a□l□a□n□c□e□,□ □E□r□i□c□ □R□a□v□u□s□s□i□n□<□B□R□ □/□>□ □1□1□.□ □M□a□c□r□o□n□u□t□r□i□e□n□t□s□,□ □E□n□e□r□g□y□ □B□a□l□a□n□c□e□,□ □a□n□d□ □B□o□d□y□ □W□e□i□g□h□t□ □R□e□g□u□l□a□t□i□o□n□,□ □K□e□v□i□n□ □D□.□ □H□a□l□l□<□B□R□ □/□>□ □1□2□.□ □C□o□g□n□i□t□i□v□e□ □N□e□u□r□o□s□c□i□e□n□c□e□ □a□n□d□ □t□h□e□ □R□i□s□k□ □f□o□r□ □W□e□i□g□h□t□ □G□a□i□n□,□ □E□r□i□c□ □S□t□i□c□e□ □&□a□m□p□;□ □S□o□n□j□a□ □Y□o□k□u□m□<□B□R□ □/□>□ □1□3□.□ □B□o□d□y□ □W□e□i□g□h□t□ □a□n□d□ □N□e□u□r□o□c□o□g□n□i□t□i□v□e□ □F□u□n□c□t□i□o□n□,□ □M□i□s□t□y□ □A□.□ □W□.□ □H□a□w□k□i□n□s□ □&□a□m□p□;□ □J□o□h□n□ □G□u□n□s□t□a□d□<□B□R□ □/□>□ □P□s□y□c□h□o□l□o□g□i□c□a□l□ □a□n□d□ □S□o□c□i□a□l□ □F□a□c□t□o□r□s□<□B□R□ □/□>□ □1□4□.□ □A□c□q□u□i□s□i□t□i□o□n□ □o□f□ □F□o□o□d□ □P□r□e□f□e□r□e□n□c□e□s□ □a□n□d□ □E□a□t□i□n□g□ □P□a□t□t□e□r□n□s□ □i□n□ □C□h□i□l□d□r□e□n□,□ □J□e□n□n□i□f□e□r□ □O□r□l□e□t□ □F□i□s□h□e□r□ □&□a□m□p□;□ □L□e□a□n□n□ □L□.□ □B□i□r□c□h□<□B□R□ □/□>□ □1□5□.□ □P□a□r□e□n□t□a□l□ □F□o□o□d□ □R□u□l□e□s□ □a□n□d□ □C□h□i□l□d□r□e□n□&□r□s□q□u□o□;□s□ □E□a□t□i□n□g□:□ □I□n□t□e□n□d□e□d□ □a□n□d□ □U□n□i□n□t□e□n□d□e□d□ □C□o□n□s□e□q□u□e□n□c□e□s□,□ □M□y□l□e□s□ □S□.□ □F□a□i□t□h□<□B□R□ □/□>□ □1□6□.□ □P□r□e□v□a□l□e□n□c□e□ □a□n□d□ □D□e□m□o□g□r□a□p□h□i□c□s□ □o□f□ □D□i□e□t□i□n□g□,□ □A□n□d□r□e□w□ □J□.□ □H□i□l□l□<□B□R□ □/□>□ □1□7□.□ □T□h□e□ □I□m□p□a□c□t□ □o□f□ □D□i□e□t□i□n□g□,□ □D□i□a□n□n□e□ □N□e□u□m□a□r□k□-□S□z□t□a□i□n□e□r□ □&□a□m□p□;□ □K□a□t□i□e□ □A□.□ □L□o□t□h□<□B□R□ □/□>□ □1□8□.□ □W□e□i□g□h□t□ □S□u□p□p□r□e□s□s□i□o□n□,□ □M□i□c□h□a□e□l□ □R□.□ □L□o□w□e□<□B□R□ □/□>□ □1□9□.□ □O□r□i□g□i□n□s□ □o□f□ □B□i□n□g□e□ □E□a□t□i□n□g□:□ □P□e□d□i□a□t□r□i□c□ □L□o□s□s□-□o□f□-□C□o□n□t□r□o□l□ □E□a□t□i□n□g□,□ □M□a□r□i□a□n□ □T□a□n□o□f□s□k□y□-□K□r□a□f□f□<□B□R□ □/□>□ □2□0□.□ □S□o□c□i□o□c□u□l□t□u□r□a□l□ □I□n□f□l□u□e□n□c□e□s□ □o□n□ □B□o□d□y□ □I□m□a□g□e□ □a□n□d□ □E□a□t□i□n□g□ □D□i□s□t□u□r□b□a□n□c□e□,□ □A□n□n□e□ □E□.□ □B□e□c□k□e□r□<□B□R□ □/□>□ □2□1□.□ □S□t□i□g□m□a□,□ □D□i□s□c□r□i□m□i□n□a□t□i□o□n□,□ □a□n□d□ □O□b□e□s□i□t□y□,□ □R□e□b□e□c□c□a□ □M□.□ □P□u□h□l□<□B□R□ □/□>□ □2□2□.□ □B□o□d□y□ □I□m□a□g□e□,□ □O□b□e□s□i□t□y□,□ □a□n□d□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □J□.□ □K□e□v□i□n□ □T□h□o□m□p□s□o□n□ □&□a□m□p□;□ □L□a□u□r□e□n□ □S□c□h□a□e□f□e□r□<□B□R□ □/□>□ □2□3□.□ □B□o□d□y□ □D□y□s□m□o□r□p□h□i□c□ □D□i□s□o□r□d□e□r□,□ □K□a□t□h□a□r□i□n□e□ □A□.□ □P□h□i□l□l□i□p□s□<□B□R□ □/□>□ □2□4□.□ □D□o□e□s□ □A□d□d□r□e□s□s□i□n□g□ □O□b□e□s□i□t□y□ □C□r□e□a□t□e□ □R□i□s□k□ □f□o□r□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□?□,□ □K□e□n□d□r□i□n□ □R□.□ □S□o□n□n□e□v□i□l□l□e□ □&□a□m□p□;□ □S□.□ □B□r□y□n□ □A□u□s□t□i□n□<□B□R□ □/□>□ □I□I□.□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□<□B□R□ □/□>□ □C□l□i□n□i□c□a□l□ □C□h□a□r□a□c□t□e□r□i□s□t□i□c□s□ □o□f□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□<□B□R□ □/□>□ □2□5□.□ □T□h□e□ □H□i□s□t□o□r□y□ □o□f□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □R□i□c□h□a□r□d□ □A□.□ □G□o□r□d□o□n□<□B□R□ □/□>□ □2□6□.□ □C□l□a□s□s□i□f□i□c□a□t□i□o□n□ □o□f□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □B□.□ □T□i□m□o□t□h□y□ □W□a□l□s□h□<□B□R□ □/□>□ □2□7□.□ □A□n□o□r□e□x□i□a□ □N□e□r□v□o□s□a□,□ □E□v□e□l□y□n□ □A□t□t□i□a□<□B□R□ □/□>□ □2□8□.□ □S□e□v□e□r□e□ □a□n□d□ □E□n□d□u□r□i□n□g□ □A□n□o□r□e□x□i□a□ □N□e□r□v□o□s□a□,□ □S□t□e□p□h□e□n□ □W□.□ □T□o□u□y□z□ □&□a□m□p□;□ □P□h□i□l□l□i□p□a□ □J□.□ □H□a□y□<□B□R□ □/□>□ □2□9□.□ □B□u□l□i□m□i□a□ □N□e□r□v□o□s□a□,□ □P□a□m□e□l□a□ □K□.□ □K□e□e□l□<□B□R□ □/□>□ □3□0□.□ □B□i□n□g□e□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□,□ □M□i□c□h□a□e□l□ □J□.□ □D□e□v□l□i□n□<□B□R□ □/□>□ □3□1□.□ □A□v□o□i□d□a□n□t□/□R□e□s□t□r□i□c□t□i□v□e□ □F□o□o□d□ □I□n□t□a□k□e□ □D□i□s□o□r□d□e□r□,□ □R□a□c□h□e□l□ □B□r□y□a□n□t□-□W□a□u□g□h□<□B□R□ □/□>□ □3□2□.□ □N□i□g□h□t□ □E□a□t□i□n□g□ □S□y□n□d□r□o□m□e□,□ □K□e□l□l□y□ □C□.□ □A□l□l□i□s□o□n□<□B□R□ □/□>□ □3□3□.□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□ □i□n□ □M□a□l□e□s□,□ □T□h□e□o□d□o□r□e□ □E□.□ □W□e□l□t□z□i□n□<□B□R□ □/□>□ □3□4□.□ □M□e□d□i□c□a□l□ □C□o□m□p□l□i□c□a□t□i□o□n□s□ □o□f□ □A□n□o□r□e□x□i□a□ □N□e□r□v□o□s□a□,□ □P□h□i□l□i□p□ □S□.□ □M□e□h□l□e□r□<□B□R□ □/□>□ □3□5□.□ □M□e□d□i□c□a□l□ □C□o□m□p□l□i□c□a□t□i□o□n□s□ □o□f□ □B□u□l□i□m□i□a□ □N□e□r□v□o□s□a□,□ □P□h□i□l□i□p□ □S□.□ □M□e□h□l□e□r□<□B□R□ □/□>□ □3□6□.□ □M□e□d□i□c□a□l□ □C□o□m□p□l□i□c□a□t□i□o□n□s□ □o□f□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□ □i□n□ □C□h□i□l□d□r□e□n□ □a□n□d□ □A□d□o□l□e□s□c□e□n□t□s□,□ □N□e□v□i□l□l□e□ □H□.□ □G□o□l□d□e□n□<□B□R□ □/□>□ □3□7□.□ □C□o□n□n□e□c□t□i□o□n□s□ □b□e□t□w□e□e□n□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□ □a□n□d□ □O□b□e□s□i□t□y□,□ □M□a□r□s□h□a□ □D□.□ □M□a□r□c□u□s□<□B□R□ □/□>□ □E□p□i□d□e□m□i□o□l□o□g□y□ □a□n□d□ □E□t□i□o□l□o□g□y□ □o□f□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□<□B□R□ □/□>□ □3□8□.□ □E□p□i□d□e□m□i□o□l□o□g□y□ □o□f□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □H□a□n□s□ □W□.□ □H□o□e□k□<□B□R□ □/□>□ □3□9□.□ □G□l□o□b□a□l□ □M□e□n□t□a□l□ □H□e□a□l□t□h□ □a□n□d□ □P□r□i□o□r□i□t□i□e□s□ □f□o□r□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □K□a□t□h□l□e□e□n□ □M□.□ □P□i□k□e□<□B□R□ □/□>□ □4□0□.□ □T□h□e□ □G□e□n□e□t□i□c□s□ □o□f□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □C□y□n□t□h□i□a□ □M□.□ □B□u□l□i□k□ □&□a□m□p□;□ □G□e□r□o□m□e□ □B□r□e□e□n□<□B□R□ □/□>□ □4□1□.□ □R□i□s□k□ □F□a□c□t□o□r□s□ □f□o□r□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □K□a□r□i□n□a□ □L□.□ □A□l□l□e□n□ □&□a□m□p□;□ □U□l□r□i□k□e□ □S□c□h□m□i□d□t□<□B□R□ □/□>□ □4□2□.□ □E□m□o□t□i□o□n□ □R□e□g□u□l□a□t□i□o□n□ □a□n□d□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □S□t□e□p□h□e□n□ □A□.□ □W□o□n□d□e□r□l□i□c□h□ □&□a□m□p□;□ □J□a□s□o□n□ □M□.□ □L□a□v□e□n□d□e□r□<□B□R□ □/□>□ □4□3□.□ □D□i□s□t□u□r□b□a□n□c□e□s□ □o□f□ □t□h□e□ □C□e□n□t□r□a□l□ □N□e□r□v□o□u□s□ □S□y□s□t□e□m□ □i□n□ □A□n□o□r□e□x□i□a□ □N□e□r□v□o□s□a□ □a□n□d□ □B□u□l□i□m□i□a□ □N□e□r□v□o□s□a□,□ □L□a□u□r□a□ □A□.□ □B□e□r□n□e□r□ □&□a□m□p□;□ □W□a□l□t□e□r□ □H□.□ □K□a□y□e□<□B□R□ □/□>□ □4□4□.□ □C□o□g□n□i□t□i□v□e□ □N□e□u□r□o□s□c□i□e□n□c□e□ □a□n□d□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □J□o□a□n□n□a□ □E□.□ □S□t□e□i□n□g□l□a□s□s□<□B□R□ □/□>□ □T□r□e□a□t□m□e□n□t□ □a□n□d□ □P□r□e□v□e□n□t□i□o□n□ □o□f□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□<□B□R□ □/□>□ □4□5□.□ □A□s□s□e□s□s□m□e□n□t□ □o□f□ □F□e□e□d□i□n□g□ □a□n□d□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □J□e□n□n□i□f□e□r□ □J□.□ □T□h□o□m□a□s□<□B□R□ □/□>□ □4□6□.□ □C□o□g□n□i□t□i□v□e□ □B□e□h□a□v□i□o□r□ □T□h□e□r□a□p□y□ □a□n□d□ □E□a□t□i□n□g□ □D□i□s□o□r□d□e□r□s□,□ □C□h□r□i□s□t□o□p□h□e□r□ □G□.□ □F□a□i□r□b□u□r□n□<□B□R□ □/□>□ □4□7□.□ □I□n□t□e□r□p□e□r□s□o□n□a□l□ □P□s□y□c□h□o□t□h□e□r□a□p□y□,□ □D□e□n□i□s□e□ □E□.□ □W□i□l□f□l□e□y□ □&□a□m□p□;□ □D□a□w□n□ □M□.□ □E□i□c□h□e□n□<□B□R□ □/□>□ □4□8□.□ □F□a