Statistical Aspects Of The Design And Analysis Of Clinical Trials

Inbunden, Engelska, 2000

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Beskrivning

About 8000 clinical trials are undertaken annually in all areas of medicine, from the treatment of acne to the prevention of cancer. Correct interpretation of the data from such trials depends largely on adequate design and on performing the appropriate statistical analyses. In this book, the statistical aspects of both the design and analysis of trials are described, with particular emphasis on recently developed methods of analysis.

Produktinformation

Utgivningsdatum:2000-02-12
Mått:161 x 240 x 23 mm
Vikt:693 g
Format:Inbunden
Språk:Engelska
Antal sidor:352
Förlag:Imperial College Press
ISBN:9781860941535

Utforska kategorier

Matematisk statistik inom Naturvetenskap och teknik
Tillämpad matematik inom Naturvetenskap och teknik
Farmakologi inom Medicin

Recensioner i media

"... given a keen amateur interest and an ability to skip the occasional rather daunting-looking equation this book is surprisingly accessible ... There's an introductory chapter containing an excellent historical overview." Transactions of Royal Society of Tropical Medicine and Hygiene, 2001

Innehållsförteckning

An introduction to clinical trials; treatment allocation, the size of trials and reporting results; monitoring trial progress - outcome measures, compliance, dropouts and interim analyses; basic analyses of clinical trials, the generalized linear model and the economic evaluation of trials; simple approaches to the analysis of longitudinal data from clinical trials; models for non-normal longitudinal data from clinical trials; survival analysis; Bayesian methods; meta-analysis.