Epilepsy Aphasia Spectrum

Thierry Deonna, Emeritus Professor of Neurology, the Child Neurology Unit, University of Lausanne Children's Hospital,the University of Lausanne, Switzerland. Eliane Roulet-Perez, Professor of Paediatric Neurology at the Faculty of Biology and Medicine, University of Lausanne, Switzerland. Head of the Paediatric Neurology and Neurorehabilitation Unit, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

• Authors’ Appointments vii Forewords ixPreface xiAcknowledgements xiii1. Introduction 12. History of the Landau–kleffner Syndrome 43. Classification Issues 184. Speech Perception and Brain Organization of Language: Relevant Features for Landau–kleffner Syndrome and The Epilepsy-aphasia Spectrum 265. The Different Clinical Facets of Landau–kleffner Syndrome 346. Developmental Aspects of Landau–kleffner Syndrome and The Epilepsy-aphasia Spectrum and The Overlap with Developmental Language Disorders and Autism Spectrum Disorder 607. Evolution of Landau–kleffner Syndrome: Short-,mid- and long-term Outcomes 708. From Rolandic Epilepsy to Landau–kleffner Syndrome 789. Laboratory Investigations in Landau–kleffner Syndrome and The Epilepsy-aphasia Spectrum 9510. Physiopathology of Speech, Language and Other Prolonged Epileptic Dysfunction in Landau–kleffner Syndrome, Epilepsy with Continuous Spike Waves During Sleep and Related Syndromes 10611. Functional Neuroimaging Investigations in Idiopathic Focal Epilepsies of Childhood with Cognitive and Behavioural Impairment 119 Xavier de Tiège, Serge Goldman, and Patrick van Bogaert12. Drug Management of Cognitive Impairments in Landau–kleffner Syndrome and Other Epilepsy Aphasia Spectrum Syndromes 12713. Speech and Language, Educational and Psychological Remediation 13714. Personal Testimonies and Unpublished Cases 15615. Summary and Conclusions 167References 170Index 187