Direct Mechanisms in Cholesterol Modulation of Protein Function

AvAvia Rosenhouse-Dantsker,Anna N. Bukiya

Inbunden, Engelska, 2019

Del 1135 i serien Advances in Experimental Medicine and Biology

1 073 kr

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Beskrivning

In this book, renowned scientists describe how cholesterol interacts with various proteins. In the second part of the book, examples of cholesterol binding sites and consequences of specific cholesterol recognition for protein function are presented for G protein-coupled receptors, ion channels and cholesterol-transporting proteins.

Produktinformation

Utgivningsdatum:2019-05-27
Mått:155 x 235 x 16 mm
Vikt:442 g
Format:Inbunden
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:168
Förlag:Springer Nature Switzerland AG
ISBN:9783030142643

Utforska kategorier

Biokemi inom Naturvetenskap och teknik

Innehållsförteckning

Introduction.- Direct binding of cholesterol to proteins.- Cholesterol-recognition motifs in membrane proteins.- Molecular determinants of cholesterol binding to proteins: overview of crystallographic studies.- Crystallographic studies of steroid-protein interactions.- Insights into cholesterol binding sites in proteins from computational studies.- Cholesterol binding to NPC1/NPC2.- I Biophysical elements of the interaction between cholesterol and the nicotinic acetylcholine receptor.- Modulation of TRPV1 channels by cholesterol.- Cholesterol binding sites in inwardly rectifying potassium channels.