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Beskrivning
Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes.
Harald Seitz has been a group leader at the Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses in Potsdam-Golm since 2012. He received his PhD (2000) and Diploma (1997) from the Free University Berlin and his postdoctoral degree (Habilitation (2012) from the University of Kassel. He worked for more than 10 years at Max-Planck Institute for Molecular Genetics in Berlin and moved in 2012 to the Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses. His work chiefly focuses on the (bio)analysis of different samples such as human serum or environmental samples using a variety of methods.
Innehållsförteckning
RNA G-Quadruplexes as key Motifs of the Transcriptome.- Challenges and Perspectives in Nucleic Acid Enzyme Engineering.- Strategies for Characterization of Enzymatic Nucleic Acids.- Bioanalytical Application of Peroxidase Mimicking DNAzymes: Status and Challenges.- Hemin/G-Quadruplex Horseradish Peroxidase-Mimicking DNAzyme: Principle and Biosensing Application.- Aptazymes: Expanding the Specificity of Natural Catalytic Nucleic Acids by Application of In Vitro Selected Oligonucleotides.