From Obesity to Diabetes

Inbunden, Engelska, 2022

Del 274 i serien Handbook of Experimental Pharmacology

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Beskrivning

Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems.

Produktinformation

Utgivningsdatum:2022-07-22
Mått:155 x 235 x 32 mm
Vikt:1 041 g
Format:Inbunden
Språk:Engelska
Serie:Handbook of Experimental Pharmacology
Antal sidor:513
Förlag:Springer Nature Switzerland AG
ISBN:9783030999940

Utforska kategorier

Innehållsförteckning

Part I Obesity. Epidemiology of Obesity.- The Circadian Clock and Obesity.- Nutrition and Microbiome.- From Obesity to Diabetes: The Role of the Adipose Organ.- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy.- The Enteroendocrine System in Obesity.- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches.- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction.- Obesity, Senescence, and Senolytics.- Obesity and Obstructive Sleep Apnea.- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance.- Islet Inflammation and β Cell Dysfunction in Type 2 Diabetes.- NAFLD and NASH: The Metabolically Diseased Liver.- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities.- Diabetic Peripheral Neuropathy.- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies.- PhysicalActivity, Obesity and Weight Loss Maintenance.- Bariatric/Metabolic Surgery.- Drugs for Treating Obesity.- Novel Drugs for Diabetes Therapy.- Novel Approaches to Restore Pancreatic Beta-Cell Massand Function.- Precision Medicine and Obesity.- Targeting the Enteroendocrine System for Treatment of Obesity.