This edited collection explores Dante Alighieri’s contribution to medical, scientific, and spiritual thought in medieval and early modern times. The chapters address how Dante shaped an understanding of the human body and mind, his relationship with medical and scientific thought in his literary and philosophical production, and his legacy which continued into the following centuries. Each chapter questions Dante’s contribution to these issues from an interdisciplinary perspective, thus putting medieval literatures in conversation with the history of medicine and science, politics, theology, and philosophy. Covering questions on the body, soul, matter, politics, and physics, this valuable book presents an overview of Dante’s relationship with medical thought and the medieval sciences.