Linda M. Collins is Distinguished Professor of Human Development and Family Studies, Professor of Statistics, and the director of The Methodology Center at the Pennsylvania State University. She is interested in most aspects of research methods.  Her current work focuses on experimental and non-experimental design, particularly for building, optimizing, and evaluating behavioral, biobehavioral, and biomedical interventions. Professor Collins also has a long-standing interest in models for longitudinal data, particularly latent transition analysis, and other latent class models.

• 1 Conceptual Introduction to the Multiphase Optimization Strategy (MOST).-  2 The Preparation Phase of MOST.- 3 Introduction to the Factorial Optimization Trial.-  4 Interactions Between Components and Moderation of Component Effects.-  5 Balanced and Unbalanced Reduced Factorial Designs.- 6  Gathering Information for Decision-Making in the Optimization Phase: Resource Management and Practical Issues.-  7 The Completion of the Optimization Phase.-  8 Introduction to Adaptive Intervention.

Linda M. Collins is Distinguished Professor of Human Development and Family Studies, Professor of Statistics, and the director of The Methodology Center at the Pennsylvania State University. She is interested in most aspects of research methods.  Her current work focuses on experimental and non-experimental design, particularly for building, optimizing, and evaluating behavioral, biobehavioral, and biomedical interventions. Professor Collins also has a long-standing interest in models for longitudinal data, particularly latent transition analysis, and other latent class models.

• 1 Conceptual Introduction to the Multiphase Optimization Strategy (MOST).-  2 The Preparation Phase of MOST.- 3 Introduction to the Factorial Optimization Trial.-  4 Interactions Between Components and Moderation of Component Effects.-  5 Balanced and Unbalanced Reduced Factorial Designs.- 6  Gathering Information for Decision-Making in the Optimization Phase: Resource Management and Practical Issues.-  7 The Completion of the Optimization Phase.-  8 Introduction to Adaptive Intervention.