Modern Proteomics – Sample Preparation, Analysis and Practical Applications

Häftad, Engelska, 2018

Del 919 i serien Advances in Experimental Medicine and Biology

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Beskrivning

The various applications of proteomics technologies in biological and medical sciencesThis book should appeal to anyone with an interest in proteomics technologies, proteomics related bioinformatics and proteomics data generation and interpretation.

Produktinformation

Utgivningsdatum:2018-05-04
Mått:178 x 254 x 28 mm
Vikt:1 134 g
Format:Häftad
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:533
Förlag:Springer International Publishing AG
ISBN:9783319823577

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik

Innehållsförteckning

Sample Origin.- Sample Preparation for Proteomic Analyses by Mass Spectrometry.- Plant structure and specificity - challenges and sample preparation considerations for proteomics.- Protein Fractionation and Enrichment for Proteomics.- High Performance Liquid Chromatography.- Mass Analyzers.- Top-Down Mass Spectrometry: Proteomics to Proteoforms.- Platforms and pipelines for Proteomics Data Management and Analysis.- Visualization, inspection and interpretation of shotgun proteomics identification results.- Tandem mass spectrum sequencing: an alternative to database search engines in shotgun proteomics.- Protein Inference.- Modification Site Localization in Peptides.- Quantification.- Bioinformatics Tools for the Analysis of Proteomics Data.- Useful Web Resources.- Top-Down Mass Spectrometry: Proteomics to Proteoforms.- Protocol for Standardizing High-to-Moderate Abundance Protein Biomarker Assessments through an MRM-with-Standard-Peptides Quantitative Approach.- Posttranslational Modifications (PTMs) analysis.- Protein-Protein Interaction.- Structural Analysis.- Introduction to Proteomic-Derived Biomarkers.- Discovery of Candidate Biomarkers.- Statistical Approaches to Candidate Biomarker Panel Selection.- Qualification and Verification of biomarker candidates.